-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
May 01, 2013 - The study investigators performed
double data abstraction on each article. … For all articles, the reviewers extracted information on
study characteristics (e.g., study design, … Study Quality
We reported study quality separately for the full-length
publications and the abstracts … , because the abstracts had
limited information about study methods. … Error count of radiopaque
markers in colonic segmental transit time study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_executive.pdf
February 01, 2013 - For a single study with precise results, we graded
it as low. … Having a study design less rigorous than a controlled
trial did not drive our decision to drop a study … A third study found mixed results.33 One study
found evidence of benefit for the intervention arm on … The study authors typically evaluated short-term outcomes. … Support for Students
Exposed to Trauma: a Pilot Study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - Study and patient characteristics may account for
some or all of the between-study differences we observed … Data were available for
gabapentin (one study), opioids (multiple opioids, one
study; methadone, one … study) and dopamine agonists. … This study found no benefit. … (effect-RLS study).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
February 22, 2012 - Risk of bias (how the study type and study design and conduct may have contributed to
systematic error … Was the study described as double blind? Y / N
3. … Study Attrition
- The proportion of sample completing the study and providing
outcome data is adequate … - Adequate study sample has complete data for prognostic factors. … - The method and setting are the same for all study participants.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
October 05, 2018 - Study Inclusion Criteria
Category Entry Criteria
Study Population • Include:
Adults aged >50 years … framework and study-specific entry criteria (Table 3). … design and risk of bias,
study limitations will be rated as low, medium, or high. … / (169001)
53 exp case control study/ (139905)
54 family study/ (27182)
55 longitudinal … study/ (108891)
56 retrospective study/ (601258)
57 prospective study/ (419321)
58 cohort
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
September 20, 2013 - Data from each eligible study will be extracted by a single reviewer. … populations, diagnostic methods, and outcomes
among study designs. … GOSH–a
graphical
display
of
study
heterogeneity.
… comparison or parallel design or control group or
prospective study or retrospective study or case … control study or major
clinical study).de. or Case control studies/ or Cohort/ or Longitudinal
studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Thus,
across-study comparisons of subgroup factors are limited. … Most specific comparisons
were made by one study only. … Across this study set, four classes were evaluated
(FXaI, LMWH, UFH, placebo). … within-study comparisons of different patients based on
these characteristics. … Most
specific comparisons were addressed by only one study.
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Thus,
across-study comparisons of subgroup factors are limited. … Most specific comparisons
were made by one study only. … Across this study set, four classes were evaluated
(FXaI, LMWH, UFH, placebo). … within-study comparisons of different patients based on
these characteristics. … Most
specific comparisons were addressed by only one study.
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
July 08, 2015 - Exclusion Criteria:
Study Design: Observational study designs with no comparison group (case reports … One prospective study cohort study of patients >65 who underwent hip fracture without
preoperative delirium … Urinary retention (2 RCTs, n = 62; 1 cohort
study, n = 535). … Up-to-date One prospective study cohort study of patients >65 who underwent hip fracture
without preoperative … ;DESIGN: Prospective study of
consecutive patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
January 01, 2010 - In a study of nine U.S. … The study
findings were consistent, the outcomes were direct, and
study findings were precise. … study by
Ellingson and colleagues.28 The study by Chaberny and
colleagues32 utilized a before/after … study design. … The study findings were
consistent, the outcome was indirect, and study findings
were imprecise.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
February 17, 2016 - The main differences relate to dropping Key
Questions related to placebo (no prophylaxis) study arms … design
• Randomized controlled trials (any study size)
(KQ 1-6)
• Nonrandomized comparative … observational studies (N ≥750 total per study)
(KQ 1-4, 6)
Timing
• Any duration of follow-up … Data Extraction and Data Management: Each study will be extracted by one
methodologist. … , results, and study quality.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - Empirical study. … VIGOR
Study Group [see comment]. … Celecoxib Long-term Arthritis Safety Study
[see comment]. … Performance of
propensity score calibration—a simulation
study. … Did the study specify WHO collected the harms?
8.
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effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - Empirical study. … VIGOR
Study Group [see comment]. … Celecoxib Long-term Arthritis Safety Study
[see comment]. … Performance of
propensity score calibration—a simulation
study. … Did the study specify WHO collected the harms?
8.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - Page 26
of 230, lines 16-17 states that limitations in study
design were based on study design and … limitations are assessed:
“Study limitations were rated as low, medium, or
high based on study design … Study selection and exclusion seem appropriate. … Did you check each study for multiple
outcomes? … To
cite one example, if a study is shorter than 6 months,
the reviewers argue that the study cannot
-
effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - Page 26
of 230, lines 16-17 states that limitations in study
design were based on study design and … limitations are assessed:
“Study limitations were rated as low, medium, or
high based on study design … Study selection and exclusion seem appropriate. … Did you check each study for multiple
outcomes? … To
cite one example, if a study is shorter than 6 months,
the reviewers argue that the study cannot
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - Strength training and treadmill walking improved IRLS
symptoms but adherence was poor and the study … One study found that the dopamine agonist cabergoline improved scores on
the IRLS symptom scale and … , study withdrawals (due to any reason)
from RCTs were slightly less common in patients randomized to … Resource use,
size, and
duration
Minimal, study can be conducted by
secondary data analysis. … The International
Restless Legs Syndrome Study Group. Mov
Disord. 1995 Sep;10(5):634-42.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
March 15, 2010 - Sleep study measures
i. Apnea hypopnea index
ii. Number of arousals
iii. … Studies of different study designs will be graded within
the context of their study design. … Nieto FJ, Young TB, Lind BK, et al, for the Sleep Heart Health Study. … Prospective study of the association between sleep-
disordered breathing and hypertension. … Population-based study of sleep-disordered breathing
as a risk factor for hypertension.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
August 01, 2018 - participants
represent and, therefore, the populations to which the
study results apply. … Efficacy of olanzapine in
acute bipolar mania: a double-blind, placebo-controlled study. … The Olanzipine HGGW Study Group.[Erratum appears in Arch
Gen Psychiatry 2002 Jan;59(1):91]. … Allopurinol augmentation in
the outpatient treatment of bipolar mania: a pilot study. … Divalproex
Maintenance Study Group. Arch Gen Psychiatry. 2000
May;57(5):481-9.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
February 04, 2014 - The standard
variables for subgroup/sensitivity analyses are study size, study quality, and
treatment … Score as one of three
levels, separately by
type of study design:
• Low level of
study limitations … • Medium level of
study limitations
• High level of
study limitations
Directness Required Directness … Score as one of three
levels:
• Consistent
• Inconsistent
• Unknown (e.g.,
single study)
Single-study … It includes:
• Study publication bias (i.e.,
nonreporting of the full study)
• Selective outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - Prevalence of atrial fibrillation in elderly
subjects (the Cardiovascular Health Study). … Atrial fibrillation as an independent risk factor for
stroke: the Framingham Study. … The
Framingham Study. Stroke 1996;27(10):1760-4. PMID: 8841325.
13. … (Catheter Ablation For The Cure Of Atrial Fibrillation Study). … Catheter ablation versus antiarrhythmic drugs for
atrial fibrillation: the A4 study.