-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
March 01, 2012 - ),
hormone replacement therapy (one study), living
at home (one study), intertrochanteric fracture … (one
study), subtrochanteric fracture (one study), increased
hemoglobin (one study), personal or familial … history of
VTE, (one study), and varicose veins (one study). … ), and gender (one study showed
a significant increase in females while one study showed
gender had … One
observational study supported this finding but another
study suggested a decrease in the number
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
February 01, 2012 - We did not ask stakeholders to rank study designs or provide
input to the proposed study designs. … Research question is a statement of the purpose of a study. … Retrospective
Study
A study in which a group of individuals is
identified by predetermined common … O
th
er
Case Control
Study
A study in which participants are
identified based on the known outcomes … Otherwise, issues are minimal,
given study is observational.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - Study inclusion criteria fecal incontinence
Category Criteria for Study Inclusion
Population • Enrolled … adults (age 18 and older) with fecal incontinence (FI) at the time of study
enrollment in studies … Study limitations will be rated as low, moderate, or high according to study design and
conduct. … Prospective study of conservative and operative
treatment for faecal incontinence. … Study design:
prospective,
retrospective, or mixed?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - This
study focused on the most commonly used
measures. … Study sample sizes are included in Tables 4,
5, and 6. … Study
characteristics are adequately described. … study design. … We added a statement that the leflunomide
vs. methotrexate study was a non-inferiority
study design
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
October 01, 2014 - Neurocognitive outcomes in the treatment of early-onset
schizophrenia spectrum disorders study. … Advances in the Study of Behavior 4. Journal of Child Psychology and Psychiatry 4. … Neurocognitive outcomes in the treatment of early-
onset schizophrenia spectrum disorders study. … RESULTS:
The study randomized 78 children; 55 completed the study. … found highlighted the study vs. placebo for mania.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
March 01, 2012 - New observational
study?
Analysis of existing
data?
Model? … New observational
study?
Analysis of existing
data?
Model? … New observational
study?
Analysis of existing
data?
Model? … of observational data, then
design of a new study would be the next most valid and feasible study … Observational Study—Analysis of Existing Data
If a new observational study is not feasible, there may
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disparities-quality-improvement_research-protocol.pdf
February 23, 2012 - The study must include populations in which the
purpose of the study is to examine a change in disparity … Study Design. … In all
cases, the study must assess whether or not a disparity was reduced.
Study Groups. … We will record quality assessments in tables,
summarizing each study. … (e.g., RCT, prospective
observational study).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - The overall judgment of risk
of bias was based on the overall study conduct, specifically
relating … the study
was particularly large, robust, and of good quality. … No firm conclusions were drawn from this
single, high-risk-of-bias study. … No firm
conclusions were drawn from this single, high-risk-of-bias
study. … The other
study compared the use of IVUS after PTCA with PTCA without
IVUS.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
December 06, 2010 - If both reviewers agree that a study does not meet
the eligibility criteria, the study will be excluded … In
general terms, a “good” study has the least bias and results are considered to be valid. … A “fair” study is susceptible to some bias but probably not sufficient to invalidate its
results. … Two independent reviewers will assign quality ratings to each study. … Therefore study
questions, design and/or methodological approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
September 01, 2011 - to study. … , study
results, and the methodological quality of each study,
which was rated from A (highest quality … No study directly comparing endoscopic treatments was
identified for this update. … One available study reviewed
(the LOTUS trial) reported 3-year interim data;
that study remains ongoing … - Outcomes of study (GERD symptoms, QoL,
satisfaction, medication use, pH study results, remission
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
February 16, 2016 - We will, therefore, report what is reported in each study. … We will extract study and design characteristics (e.g., study design, year,
Source: www.effectivehealthcare.ahrq.gov … Two senior investigators will assess each included study independently. … such as age, symptom severity, or comorbidities in the study sample. … is, it describes only between-study and not between-patient variation.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - For the purpose of this document, a patient registry is
an organized system that uses observational study … Registry study designs often restrict eligibility for
entry to individuals with certain characteristics … • A plan for communication of study results is addressed. … • The target population is described, including plans to recruit study subjects. … Analysis
• Loss to followup is characterized at key stages during the conduct of the study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - ),54 metformin
(4 studies),55-58 progestogens (1 study),59 cabergoline
(1 study),60 lifestyle/behavioral … Study duration was typically 6 months or less. … ),59 triphasic birth
control pills (1 study),51 cabergoline (1 study),60 diet
and exercise (1 study … lPoor quality study: acupuncture vs. exercise (n=34) or no intervention (n=17); Fair quality study: mind … Menstrual blood
loss—a population study.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-literacy_research-protocol.pdf
January 22, 2010 - If both reviewers agree that a study does not meet the
eligibility criteria, the study will be excluded … We will design evidence tables that identify study information including study design,
methods, and … Two independent reviewers will assign quality ratings to each study. … Emergency department discharge instructions
comprehension and compliance study. … Multicenter study of limited health literacy in emergency
department patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - Several methods for improving
detection via imaging are under study. … Otherwise, the study will be considered to have high risk of
bias.
Table 12. … By default, we will give a “no” answer to each
observational study.
3. … By default, we will give a “no” answer to each
observational study. … / or retrospective study/ or case control
study/ or major clinical study/ or evaluation studies/ or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
January 26, 2015 - This would
greatly improve and clarify the framework of the study
The need for a subgroup study is … direct (within study) vs. indirect (between study)
assessments. … Additional sample selection criteria
varied per study (see Basic Study tables,
Appendices E4-E7) … Where did AHRQ get the idea that such a study, doubtless
an expensive study, would be needed? … Our write up provided key aspects of this
study including patient inclusion criteria, study design,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
July 01, 2012 - design RCTs • Non-RCT study designsa
• Not a clinical study (e.g., editorial, nonsystematic
review, … One study was conducted in
Canada and one multicenter study included sites in the
United States; all … Other
study reporting issues also affect applicability. … Adult intensive care unit use at the end
of life: a population-based study. … A prospective study
of 150 critically ill adult patients. Am J Med. 1981;70(1):65-76.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
June 10, 2013 - This study has been reclassified as a school based
study.
78 Peer Reviewer 3 Executive
Summary … E.g., if a single
study presented both, would you select BMI z-
score as the inidicator for that study … Under Methods/Study Selection we state: For inclusion in this review, we
required that the study reported … Although couched as a diabetes prevention
study, it was really an obesity prevention study,
with the … Was this an uncontrolled study?
This was a pre post study design with no control group.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
January 01, 2014 - Study Selection
Using the prespecified inclusion and exclusion criteria,
titles and abstracts were … Continuous variable outcomes reported by study authors
included means, medians, standard deviations, … may be of different quality for two
individual outcomes reported within that study. … reported no deaths
in either arm; 1 study reported 1 death in the upstream GPI arm; 1 study reported … reported HR 1.19 (0.84 to
1.68); smaller study reported 2 strokes in 300 mg group, 1 stroke in 600
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
December 16, 2014 - Yes, given the rules of
the study. … for ACM was higher in PIVOT then the
Swedish study suggests that PC death in the PIVOT study was diluted … the results as reported by the study
investigators. … , this study suffered from a number of
critical methodological flaws. … MAPPED study design: A 6 month
randomised controlled study to evaluate the
effect of dutasteride on