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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/postpartum-care-protocol-appendix%20A.pdf
    December 09, 2021 - models" OR longitudinal OR "Placebos"[Mesh] OR placebo* OR "Research Design"[Mesh] OR "Evaluation Study … " [Publication Type] OR "Comparative Study" [Publication Type] OR ((comparative OR Intervention) AND … study) OR pretest* OR posttest* OR prepost* OR "before and after" OR interrupted time* OR time serie … 'cohort studies'/exp OR longitudinal OR 8,354,777 ((comparative OR intervention) AND study) OR … " OR PT "Comparative Study" OR ((comparative OR Intervention ) AND study ) OR pretest* OR posttest*
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-surveillance-report.pdf
    July 17, 2020 - The surveillance search identified 321 citations and identified one additional study for this update … Effectiveness – SARS-CoV-2 Community settings: No evidence. 1 new observational study on mask … The new study was a retrospective cohort study of 124 households with an index SARS- CoV-2 case and 355 … Masks included N95 respirators, surgical masks, or cloth face coverings, and the study did not conduct … Literature Flow Diagram *One new study added Archived: This living report is not being updated.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
    June 15, 2010 - Sample size: There are no restrictions for study sample size. … Key study elements will be reviewed by a second person (study investigator) with respect to study outcomes … study design, sample size, sample size calculation or power estimate); clinical indications; and study … The study design elements evaluated with this tool include: selection of the study population, appropriate … and have been judged to have had an “inadequate response” at the time of entry into the study.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
    December 01, 2012 - See the full report for references to each study. 5 KQ1a. … One study was of good quality, 4 of fair quality, and 13 of poor quality. … The one good-quality study of US had an accuracy rate of 73 percent. … LHRH was compared with hCG and placebo in one study of fair quality. … Only one study assessing testicular descent was rated as good quality.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
    January 01, 2010 - Inclusion/exclusion criteria Category Criteria Study Population Low-risk pregnant women who have a … They represent 95 distinct study populations. … The most common reasons for exclusion were ineligible study design and irrelevance to the topic. … 1 (168) Moderate N/A Direct Imprecise Insufficient; 1 fair-quality study KQ2. … 1 (201) Moderate N/A Direct Imprecise Insufficient; 1 fair-quality study 11 Table B.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
    December 23, 2014 - Outcomes Mortality Recurrence (study author defined) Clearance (study author defined) Complications … Study inclusion criteria Category Criteria for Inclusion Study Enrollment Studies that enroll adults … We will summarize included study characteristics and outcomes in evidence tables. … design and risk of bias, study limitations will be rated as low, medium, or high. … Study design: prospective, retrospective or mixed?
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
    November 01, 2013 - • Study conduct. … Score as one of three levels, separately by type of study design: • Low level of study limitations … • Medium level of study limitations • High level of study limitations Directness Directness relates … It includes: • Study publication bias, i.e., nonreporting of the full study. … levels of aggregate risk of study limitations based on study conduct; the scores are low, medium, or
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
    October 01, 2016 - We stratified study data by whether they came from controlled studies (e.g., RCT, cohort studies) or … Data for study groups not restricted to highly aggressive patients (i.e., the denominator involved … designs (i.e., any study that we could rate for risk of bias). … One study addressed staff training. … Case study evaluating the impact of de-escalation and physical intervention training.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
    May 01, 2013 - , and the heterogeneity of the individual study results. … reporting 4 strokes for total study, and 1 study reporting 1 stroke in endovascular group, 2 strokes … IC-CLI-Obs (1 study, 107 patients) Inconclusive evidence due to imprecision, with 1 study reporting … IC-CLI-Obs (1 study, 107 patients) Inconclusive evidence due to imprecision, with 1 study reporting … IC-CLI-Obs (1 study, 169 patients), OR 1.00 (0.18 to 5.54) IC-CLI-RCT (1 study, 86 patients), OR 0.18
  10. MEDLINE Searches (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
    March 01, 2009 - ‡Definitions of types of outcomes: • A primary outcome is the main outcome of a study that the study … • A secondary outcome is a major outcome of a study that the study was designed and powered to demonstrate … Wrong type of study 175. Kopans DB. … D 1-2 Study* Study Design N (drug/ placebo or nonuser) Participants Dose (mg); Duration Harms … D 1-3 Study* Study Design N (drug/ placebo or nonuser) Participants Dose (mg); Duration Harms
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
    January 01, 2015 - , or high according to study design and conduct. … Included fibromyalgia subgroup studies, by study design Study Design Count Randomized controlled trials … antidepressant use (1 study), postmenopausal women (2 studies), and 1 study that used baseline Visual … of tables, and study management. … .55 Study duration ranged from 3 months to 1 year, which was the longest followup of any study included
  12. effectivehealthcare.ahrq.gov/sites/default/files/reporting.ppt
    September 01, 2009 - Executive Summary (II) Should be a distillation of the entire report Should exclude study-by-study … executive summary is meant to be a distillation of the entire review report and should not include study-by-study … One example of such bias is study level publication bias. … Results: Study Selection In reporting the study selection, authors should provide information on the … Study selection should be the first part of the Results section.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
    February 23, 2012 - Process of care reported as study outcomes: i. … ; uncontrolled pre- and post-intervention study …  For KQ 1-3, a study must report a relevant outcome. … : basic study design, geographic location, study setting including health care system, number of practices … dates, stage of study, and source of funding.
  14. Introduction (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-1_research.pdf
    February 01, 2009 - During the study period, the overall utilization of glucocorticoids decreased from 46% to 38%, whereas … This study was approved by the Institutional Review Board of Vanderbilt University and the Bureau of … Results During the study period we identified 24,250 patients with RA. … Medication Utilization The proportion of RA patients receiving at least one study medication (DMARD … Interestingly, about 10% of patients were not using any study drugs on the index dates.
  15. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - moves or changes his/her email address without notifying study staff). … Competing risks can lead to missing data in certain settings; sometimes a study may be interested in … Use of validated PROs can ensure that the surveys are clear, concise, and appropriate for the study … As an example, a study that intends to enroll college students may see a better response rate with a … the study enrollment date, before the AE resolution date, and study discontinuation date).
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
    June 01, 2017 - Terminology We use the term study to refer to the conducted research. … Design characteristics Study Study design Funding source Inclusion criteria Age range (y) Number … NCT01908803 gives no results for this outcome, citing the early termination of the study. … More precise searching may reduce associated study costs and sensitivity of the search. … Detecting and adjusting for small-study effects in meta-analysis.
  17. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
    April 20, 2022 - , unpublished study results, and ongoing studies. … For each study, we will extract publication data, study design features, population characteristics, … study designs. … Each study will be described in summary and evidence tables presenting study design features, study … We expect to primarily rely on reported within-study differences in effects (or harms).
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
    December 31, 2022 - in immunocompromised patients evaluated the neutralizing antibody response.21 In this study, 35 liver … In the largest study, conducted among a cohort of 5,230 adults in the UK with a RT-PCR cycle threshold … The study reported no data regarding the Omicron variant. … Joanna Briggs Institute cohort study checklist assessments Outcome Author, Year 1 2 3 4 … Longitudinal serology of SARS-CoV-2- infected individuals in India: a prospective cohort study.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
    April 01, 2016 - Clinician Summary STUDY DESIGN AND OUTCOME MEASURES This prospective observational study en- rolled … The study population consisted of patients who underwent lumbar spine imaging within 6 weeks of their … OTHER FINDINGS OF THE STUDY One-year use and costs of health care resources were significantly higher … Since the study was not randomized or double-blinded, there was also potential for confounding by study … The study results support a position that, regardless of age, early imaging should not be performed
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
    July 10, 2023 - the symptoms and signs evaluated, assessment tools used, and the demographics and settings of the study … Multiple publications relating to the same study will be mapped to unique study. … Cagnacci A XA, Sclauzero M, Venier M, Palma F, Gambacciani M, writing group of the ANGEL study. … Vaginal atrophy across the menopausal age: results from the ANGEL study. … Draft Population, Intervention, Comparator, Outcome, Timing, Setting/Study Design (PICOTS) B.

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