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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4.pdf
January 01, 2023 - Period: February 27, 2024, to April 28, 2024
Summary: During the current search period, one new study … The new study was assessed as high risk of bias and
had a small sample size (n=60). … New studies identified since the 2023 systematic review
Search Period Citation Risk of
Bias
N
Study … Cannabis for
chronic pain: cardiovascular safety in a nationwide
Danish study. … High 296
Prospective
cohort
Note: The first study listed is in bold because it was identified in
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-post-transplant-complications-rapid-research.pdf
May 01, 2025 - For each included primary study, we extracted the following information:
• General study characteristics … : author, year of publication, country, funding source
• Study design: study design, study population … overview of the study design and population characteristics of the
included primary study. … Since this study was a retrospective cohort study, we used the Newcastle Ottawa Scale
to assess its … Risk of Bias Assessments
The included study was a retrospective cohort study.
-
effectivehealthcare.ahrq.gov/sites/default/files/hawley-presentation.pdf
October 08, 2025 - The first study is a population-based study of colorectal cancer patients in Atlanta
and Detroit … This study was focused on trying to
understand reasons for differences in receipt of chemo therapy … One is a completed study and one is a current study, again, both
population-based, both oversampling … We were specifically interested in that issue in this
colorectal cancer study and had a whole … In this
study we asked patients, after they had completed their breast cancer treatment,
"How
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - duration or length of follow up
• Settings:
o No limitation on study setting
• Study Design:
o … duration and length of follow up None
Setting • All study settings None
Study
Design
• RCTs • … If study authors respond and report
missing study data, corrections, or other study information relevant … Study-reported inclusion and exclusion criteria
Study Characteristics
1. Year of publication
2. … Study class
3. Country/Countries of study sites
4. Site type
5. Clinical setting
6.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - Comparable THC to CBD ratio study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … High THC to CBD ratio study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … Low THC to CBD ratio study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … Other cannabinoids study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … Observational study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition
Comparison
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effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
August 13, 2012 - These assumptions
should be described in the study protocol and in
reporting final study results. … when a smaller study may
be sufficient. … the final study results. … Challenges to Developing
Study Questions and Initial
Solutions
In developing CER study objectives … questions that the study will answer
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-mental-health_research-protocol.pdf
September 01, 2016 - reported, retention, study conduct, and other details of
study design in the peer reviewed literature … Your study [xxx, has been included/is eligible for inclusion] in this
review. … We were unable to find a listing for your study on clinicaltrials.gov. … Is the study listed elsewhere on another clinical trials registry? … [If the study results are not listed in any clinical trials registry] Did you attempt to list
your study
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine_protocol-appendix_20111103.pdf
November 03, 2011 - of the Efficacy and Safety of Topiramate in the Prevention of Migraine
NCT00236561 A Study of the … NCT00665236 Craniosacral Therapy in Migraine: A Feasibility Study
NCT00714727 Set Point Acupuncture … in Adolescents
NCT00210873 An Open Label Extension of a Study of Topiramate in Chronic Migraine. … Who Either Completed or Prematurely Discontinued Due to Ineffectiveness
From Study M02-488. … NCT00850421 Pilot Study of BOTOX for Migraine Headaches
NCT00203307 A Research Study Examining the
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
October 25, 2022 - We included
four studies of topiramate and one study of
phenytoin. … We included
four studies of topiramate and one study of
phenytoin. … We included
four studies of topiramate and one study of
phenytoin. … This study (Roth
et al.) was included in the revised report. … One could study Keto diet vs
a second or 3rd med.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
May 01, 2024 - , including author, year, study design,
number of study participants, and main findings relevant to … Four studies were assessed to be at moderate risk of bias,
one study was at low risk, and one study … This study was at
moderate risk of bias. … One study of a CRE surveillance PSP also provided support for ASC.22 This pre-
post study implemented … Ann Intern Med. 2019 171:S59-S65. – Study
design - review
75.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-surgical-report-cards.pdf
November 01, 2023 - , including author, year, study design, number of study
participants, and main findings relevant to … Of these, 9 used a pre-post or longitudinal study design17,20,25-29,31,33 and 4
used stronger study … Study Quality Assessment Tools. 2020.
https://www.nhlbi.nih.gov/health-
topics/study-quality-assessment … /study-quality-assessment-tools
19
15. … Study Quality Assessment Tools. 2020.
https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
October 08, 2025 - Measurement Attrition Mitigate the Impact of Any Overall and Differential Measurement Attrition in the Study … Other Considerations: Did study report adequate treatment fidelity based on measurement by independent … Notes: Describe additional considerations specific to the study that were factored into the final ROB … used a validated PTSD assessment method
No
• Used different outcome measures for each study arm
Mixed … Yes:
• Study reported on treatment fidelity rating
No:
• Study did not report on treatment fidelity
-
effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - The main study partici-
pants on whom additional data are collected in the validation
study can be a … is not an
internal validation study in the strict sense of the term, the
study clearly contains enough … ‡Models and their relevant parameters from the validation study can be applied to the main study—this … As in our main study, the
validation study population was restricted to persons age 65
years or older … Validation Study
Main Study Validation Study
“Error-Prone”
Propensity Score
“Error-Prone”
Propensity
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd4-final-protocol.pdf
October 01, 2022 - duration or length of follow up
• Settings:
o No limitation on study setting
• Study Design:
o … duration and length of follow up None
Setting • All study settings None
Study
Design
• RCTs • … If study authors respond and report missing study data, corrections, or other
study information relevant … Proportion of participants meeting study-defined criteria for PTSD at baseline
c. … Proportion of participants who achieved study-defined PTSD diagnostic change
j.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
March 01, 2022 - Comparable THC to CBD ratio study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … High THC to CBD ratio study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … Low THC to CBD ratio study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … Other cannabinoids study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition … Observational study primary outcomes
Author, Year
Risk of Bias
Study Design
Pain Condition
Comparison
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - duration or length of followup
• Settings:
o No limitation on study setting
• Study Design: … duration and length of followup None
Setting • All study settings None
Study
Design
• RCTs • … Proportion of participants who achieved study-defined PTSD diagnostic change
j. … Did the study use intention-to-treat analysis?
j. … Did the study use adequate methods for handling missing data?
k.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
May 01, 2025 - • We only found one study reporting on potential harms from multicancer screening
tests. … We graded the strength of evidence as insufficient for harms based on this
single study. … Summary of findings and strength of evidence
KQ
Test Outcome
Number of Studies and
Study Design … We only found one study that looked at potential harms. … Blood-based tests for multicancer early
detection (PATHFINDER): a prospective
cohort study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
January 01, 2021 - duration or length of follow up
• Settings:
o No limitation on study setting
• Study Design:
o … duration and length of follow up None
Setting • All study settings None
Study
Design
• RCTs … If study authors respond and report
missing study data, corrections, or other study information relevant … Proportion of participants meeting study-defined criteria for PTSD at baseline
c. … Proportion of participants who achieved study-defined PTSD diagnostic change
j.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/mhs-IV-epc-grand-rounds-slides.pptx
January 01, 2023 - Study Type Outcome Result Population
Rocha et al. … Primary study Hospital mortality 27% reduction Adults
Factora Primary study Hospital mortality 4% average … Arrest
45
Study Study Type Outcome Result Population
Rocha et al. … Study Type Modifications Outcome Results Population
Dean et al. … Study Type Modification Outcome Results Population
Sebat et al.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-immunodeficiency-virus-rapid-response.pdf
May 01, 2025 - AHRQ did not directly
participate in the literature search, determination of study eligibility criteria … For each included primary study, we extracted the following information:
• General study characteristics … : author, year of publication, country, funding source
• Study design: study design, study population … One study was
conducted in the US,30 and two were in Brazil.31,32 Sample sizes were small. … Funding
Study Design
Sample Size
Followup
Length
Periodontitis
Definition
Study Inclusion