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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
June 01, 2017 - Terminology
We use the term study to refer to the conducted research. … Design characteristics
Study Study
design
Funding source Inclusion criteria Age range (y) Number … NCT01908803 gives no results for this outcome, citing the
early termination of the study. … More precise searching may reduce
associated study costs and sensitivity of the search. … Detecting and adjusting for small-study
effects in meta-analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - moves or changes his/her email address
without notifying study staff). … Competing
risks can lead to missing data in certain settings; sometimes a study may be interested in … Use of validated PROs can ensure that the
surveys are clear, concise, and appropriate for the study … As an example, a study that intends to
enroll college students may see a better response rate with a … the study enrollment date, before the AE resolution date, and
study discontinuation date).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
May 01, 2017 - Appendix D of the main report includes ratings
for each study.
5
Strength of the Body of Evidence … of study in class assignment (e.g.,
special education, regular classroom) were not significant. … Most studies were small (median 40 total participants/
study) and addressed variable agents. … Applicability
Study participants were generally recruited from specialty
clinical service programs … Given heterogeneity in treatment regimens, outcomes
addressed in each study, and patient populations
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
October 01, 2015 - ● Was knowledge of the allocated intervention adequately
prevented during the study? … ● Are reports of the study free of suggestion of selective
outcome reporting? … Study limitations were determined
using the following algorithm for a body of evidence. … limitations, we did not
see any pattern indicative of a trend by study quality. … One
observational study showed results similar to the RCTs.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - Applicability issues do not have to be reviewed for each study. … Affect Applicability
Study Parameters Affect Applicability
Study parameters may affect applicability … In this case, a cohort study might be more applicable for that harm. … First, judge whether or not a study is an effectiveness trial or an efficacy trial. … Study 1
Study 2
Study 3
Study 4
Higher Age
Lower Age
Study 4
Study 1
Study 3
Study 2
Scenario
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/inguinal-hernia_executive.pdf
August 01, 2012 - (Note, however, that
a more recent study, presently in press,
estimates the U.S. prevalence at
600,000 … From each included study, we extracted all important
information. … We considered all but
one study (which was the registry study) to have moderate
risk of bias. … versus
intraperitoneal onlay mesh (one study). … One study enrolled
patients aged 4 months to 16 years; the other study
enrolled patients aged 3 months
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
July 01, 2012 - before-and-after
study. … , uncontrolled pre- and postintervention study. … Data abstraction forms for KQs 1–3 included
descriptions of the study design, study population,
interventions … and comparators, financial models,
implementation methods, study outcomes, and study
quality. … This study generally showed no differences on the key outcomes addressed.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
July 28, 2010 - Other important study factors:
1. What was the study design?
2. What was the sample size?
3. … In what country was the study done?
6. What was the funding source for the study?
4. … year of publication, source of study funding, study design
characteristics, study population (including … Study Population and Relationship to MPP and Comparison groups
Study
MPP Population
(duration … General Study Factors
Study
Design (RCT, CCT,
Uncontrolled
Observational,
Case Report/Case
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
November 01, 2010 - with strong study designs. … We re-examined the quality scoring for that particular study and
agree that the study should not have … The
Kasari et al study is one such study. Yoder and
Stone, 2006 is another. … et al. (2010) study as
only fair. … In most
other, study by study description, mere
significance or lack thereof is used to talk about
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
November 01, 2012 - Reasons for exclusion were
coded as non-English language study; pre-1995 study; not
a geographical … • One study provided insufficient evidence for the HCBS versus NH comparison; this study found that … • One study provided insufficient evidence for the HCBS versus NH comparison; this study found that … • One study provided insufficient evidence for the HCBS versus NH comparison; this study found that … • One study provided insufficient evidence for the HCBS versus NH comparison; this study found that
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tech-brief-31-mobile-applications-self-mgmt.pdf
May 01, 2018 - Study quality. … Study quality. … Study quality. … Study quality. … Study quality.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - Criteria
Study design • Controlled studies (randomized trials, cohort studies, case-
control studies … ), pooled patient-level meta-analyses, or
systematic reviews and study-level meta-analysesb
• Study … reports an ovarian cancer outcome of interest and
was published on or after Jan. 1,1990d
– Study … We stratified analyses by study
type (i.e., case-control, cohort, pooled analyses). … We excluded study datasets that reported fewer
than three duration categories; reported odds ratios
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effectivehealthcare-admin.ahrq.gov/sites/default/files/worker-health_executive.pdf
April 01, 2016 - We recorded characteristics of study populations,
interventions, comparators, settings, study designs … Two independent reviewers assessed the risk of bias
for each study. … Work Settings and Populations
No study enrolled workers from States in the
Southwest; only one study … Process evaluation
results from the Healthy Directions-Small Business study. … The COMPASS pilot study: a
Total Worker Health™ intervention for home care workers.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer30_hip-fracture-pain-executive-summary_20110517.pdf
May 01, 2011 - The
mean age of study participants ranged from 59.2 to
86.3 years. … In one cohort study (n = 291), there were no reports of
adverse effects. … In one cohort
study (n = 182), there were no reports of adverse
effects. … Mortality was reported in one
study (n = 106). … Data were reported in one
study (n = 106).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
March 31, 2010 - Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model: … Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model: … Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model: … Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model: … Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model:
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
July 01, 2012 - At the first level, they model the counts of the 2×2
table within each study, which accounts for within-study … Systematic
reviewers are encouraged to look at study characteristics and think through how study
characteristics … Another
option is to use all available thresholds per study. … (they show only a few thresholds that could be extracted from
the study). … Explore between-study heterogeneity.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
October 01, 2012 - Key Question 1b: Evidence About Settings
For the hospice setting, one study on training caregivers … For the
nursing home setting, one study of a provider education
intervention showed a statistically … study found
no impact on measures of quality of care. … We found one study focusing on
organizational change (a before-after study of a rapid-
response clinic … One study was an
RCT based on an initial non-RCT.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
March 25, 2013 - Followup
Study. … The 2011 study updates the 2001 study. (Field AE,
Wing RR, Manson JE, Spiegelman DL, Willett WC. … study design and execution. … to study long-
term weight gain. … Only the Nurses Health
Study 1 and 2 and Health Professionals Followup Study had
information.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - This study evaluated a unique
intervention to promote mother-infant bonding. … One study is of good
quality, three of fair quality, and nine of poor quality. … Neither study showed that the intervention in the trial was
effective. … One study enrolled adolescents
only, six studies targeted income-specific groups, and
one study specifically … • Identification of the underlying study purpose.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
June 01, 2013 - In all such cases, only
1 study was included to avoid oversampling. … The decision to include a study was based on the nature of the study design (preference of randomized … confirmation from any other study. … • OS is the primary direct outcome for any cancer intervention study. … Rating the quality of evidence—study limitations (risk of bias).