-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - Outcomes Mortality
Recurrence (study author defined)
Clearance (study author defined)
Complications … Study inclusion criteria
Category Criteria for Inclusion
Study Enrollment Studies that enroll adults … We will summarize included study characteristics and outcomes in evidence tables. … design and risk of bias, study
limitations will be rated as low, medium, or high. … Study design:
prospective,
retrospective or
mixed?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - • Study conduct. … Score as one of three levels,
separately by type of study design:
• Low level of study limitations … • Medium level of study limitations
• High level of study limitations
Directness Directness relates … It includes:
• Study publication bias, i.e., nonreporting of the full
study. … levels of aggregate risk of study limitations based on study
conduct; the scores are low, medium, or
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - A single reviewer
extracted data from each eligible study. … Additional
study details are available in the SRDR. … “Other” denotes one study using grid guidance and one study that
did not report information on the use … to study setting
are common for all patients within the same study and
other patient differences can … was performed, whether multiple centers
10
contributed patients to a study, study design, and risk
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
October 01, 2016 - We stratified
study data by whether they came from controlled studies
(e.g., RCT, cohort studies) or … Data for study groups
not restricted to highly aggressive patients (i.e., the
denominator involved … designs (i.e., any study that we could rate for risk of
bias). … One study addressed staff training. … Case study evaluating the impact of
de-escalation and physical intervention training.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-1_research.pdf
February 01, 2009 - During the study period, the overall utilization of glucocorticoids decreased from 46% to
38%, whereas … This study was approved by the Institutional Review Board of Vanderbilt University and the
Bureau of … Results
During the study period we identified 24,250 patients with RA. … Medication Utilization
The proportion of RA patients receiving at least one study medication (DMARD … Interestingly, about 10% of patients were not using any study drugs on
the index dates.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
March 01, 2009 - ‡Definitions of types of outcomes:
• A primary outcome is the main outcome of a study that the study … • A secondary outcome is a major outcome of a study that the study was designed and powered to demonstrate … Wrong type of study
175. Kopans DB. … D
1-2
Study*
Study
Design
N (drug/
placebo or
nonuser) Participants
Dose (mg);
Duration Harms … D
1-3
Study*
Study
Design
N (drug/
placebo or
nonuser) Participants
Dose (mg);
Duration Harms
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
October 01, 2010 - The reported measures or study design could prescribe the choice of effect measures. … 1 0/10 (0, 0.31) 0/20 (0, 0.168)
Study 2 0/100 (0, 0.036) 0/500 (0, 0.007)
Study 3 0/1000 (0, 0.004 … is, it describes only between-study, not between-
patient, variation. … apply equally to all patients in a study, e.g., study
design, quality and definition of outcomes, … Bayesian approaches to random-effects
meta-analysis: a comparative study.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
October 01, 2010 - The reported measures or study design could prescribe the choice of effect measures. … 1 0/10 (0, 0.31) 0/20 (0, 0.168)
Study 2 0/100 (0, 0.036) 0/500 (0, 0.007)
Study 3 0/1000 (0, 0.004 … is, it describes only between-study, not between-
patient, variation. … apply equally to all patients in a study, e.g., study
design, quality and definition of outcomes, … Bayesian approaches to random-effects
meta-analysis: a comparative study.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
February 23, 2012 - Process of care reported as study outcomes:
i. … ; uncontrolled pre- and post-intervention
study … For KQ 1-3, a study must report a relevant outcome. … : basic study design, geographic location, study setting
including health care system, number of practices … dates, stage of study, and source of funding.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
June 01, 2017 - Variables abstracted were:
• Date of completion
• Number of study arms
• Intervention description … • Study design
• Outcomes measures and results prioritized in the Management of Infertility SR
• … Matching was performed
initially by a research assistant, and reviewed by a study investigator. … Full text reviewed
and study included in Management of
Infertility SR. … • The study design and number of study arms matched for all eight studies.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/reporting.ppt
September 01, 2009 - Executive Summary (II)
Should be a distillation of the entire report
Should exclude study-by-study … executive summary is meant to be a distillation of the entire review report and should not include study-by-study … One example of such bias is study level publication bias. … Results: Study Selection
In reporting the study selection, authors should provide information on the … Study selection should be the first part of the Results section.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
April 01, 2016 - Clinician Summary
STUDY DESIGN AND
OUTCOME MEASURES
This prospective observational study en-
rolled … The study population consisted of patients
who underwent lumbar spine imaging
within 6 weeks of their … OTHER FINDINGS OF THE STUDY
One-year use and costs of health care resources were significantly higher … Since the study was not randomized or
double-blinded, there was also potential for confounding by study … The study results support a position that,
regardless of age, early imaging should not be performed
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
January 01, 2015 - , or high according to study design and conduct. … Included fibromyalgia subgroup studies, by study design
Study Design Count
Randomized controlled trials … antidepressant use (1 study),
postmenopausal women (2 studies), and 1 study that
used baseline Visual … of tables, and study
management. … .55 Study duration ranged from 3
months to 1 year, which was the longest followup of any
study included
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - The longest duration of followup after the
end of treatment was 60 months in one study. … No study reported
an increase in bleeding or worsening in hemoglobin
or hematocrit. … In the
8
longer study there was no further growth between 6 and 12
months. … One
study reported no transfusions among 48 participants. … One study reported faster recovery (mean 22 days)
after laparoscopic hysterectomy.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
October 12, 2016 - As part of the review process, we assess
the study quality (risk of bias) of each
study in duplicate … Thank you for identifying this study. … The outcomes of the study by Morales
were considered beyond the scope of the
study because we were … Moreover,
the outcomes of the study were
considered beyond the scope of our
review, as the study considered … One of the two studies was
superseded by a longer-term follow-up
study, and the other was a study of
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
July 01, 2010 - Comparative
studies were considered appropriate to combine in a
meta-analysis if the study design, study … The mean age of
study participants ranged from 41.2 to 80 years. … Males
comprised an average of 64.6 percent of study
participants. … Males comprised an average of 58.9 percent of study
participants. … Males represented 55 percent of study
participants.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - Study Selection
To calibrate reviewer agreement and consistency in
study selection, kappa values were … The data extracted into evidence tables
included study design; year, setting, duration, and
study inclusion … A second team member verified all study data
extraction for accuracy and completeness. … As with our ratings of individual study quality, we used
the term “quality” in lieu of “risk of bias … Prevention of serious infectious
complications was not reported as an outcome in any
included study
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/presentation.ppt
August 01, 2009 - Example:
Summary Table of Study Characteristics
A basic summary table is the “study characteristics” … design, geographic location, funding source, and other study characteristics. … Example: Summary Table of Study Characteristics
Example: Summary Table of Study Characteristics
Balk … The color code of each cell is based on what is reported by each study. … Key Messages
Summary tables and evidence maps provide key information on study characteristics and study
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
August 01, 2012 - Below are the eligibility criteria for study inclusion. … study results,
we rated the risk of bias (methodological quality) of
each study from A (highest quality … , or animal study. … determine
the study design. … The study heterogeneity observed,
with variations in study design and population as well as
inconsistency
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
September 20, 2013 - Data from each eligible study will be extracted by a single reviewer. … populations, diagnostic methods, and outcomes
among study designs. … GOSH–a
graphical
display
of
study
heterogeneity.
… comparison or parallel design or control group or
prospective study or retrospective study or case … control study or major
clinical study).de. or Case control studies/ or Cohort/ or Longitudinal
studies