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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
    August 01, 2012 - • Study withdrawals and time to withdrawal because of AEs. … When there were multiple reports of the same study, we referenced the primary or most relevant study … Results Description of Included Studies The searches identified 9,411 unique study reports. … bIncludes 1 cohort study and 1 nRCT. cIncludes 1 nRCT. Note: n = 125. … The NIMH-CATIE Schizophrenia Study: what did we learn? Am J Psychiatry. 2011;168(8):770-5.
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/suicide-prevention_research.pdf
    October 01, 2016 - We did not limit study inclusion by study population size or study design. … (if applicable) Author, Year Study design Study start and end dates Setting Study location … (if applicable) Author, Year Study design Study start and end dates Setting Study location … (if applicable) Author, Year Study design Study start and end dates Setting Study location … (if applicable) Author, Year Study design Study start and end dates Setting Study location
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
    November 01, 2013 - Study Selection For KQs 1, 2, and 7, the only excluded study design was the case report. … Table A shows study selection criteria. … Results from the 19 Breathing Not Properly Multinational Study. … Results from the Breathing Not Properly Multinational Study. … Study. J Am Coll Cardiol. 2010;56(25):2090-100. 170.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
    April 01, 2012 - applied a different reference standard to a subset of participants enrolled in the study. … KQ6 We did not identify any study addressing the harms associated with screening for OAG. … The risk of bias of diagnostic study designs is an additional concern. … : the Tajimi Study. … Population and high-risk group screening for glaucoma: the Los Angeles Latino Eye Study.
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
    June 01, 2012 - Analytic Framework Given the heterogeneity in key aspects of study design across the four Key Questions … Next, two researchers independently reviewed study abstracts to determine whether the study should … The third study assessed the effectiveness of a centralized public information system implemented in … A single study tested a strategy for augmenting scarce resources during an MCE. … ) • Hospital-based case managers to ensure care coordination Decontamination (1 study) • Strategies
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/health-information-exchange_executive.pdf
    December 01, 2015 - lowering our confidence in the study results). … Outcomes assessment of the regional health information exchange: a five-year follow-up study. … A case study. Comput Methods Programs Biomed. 2008;91(2):175-81. PMID: 18514363. 34. … Case Study Report. (Prepared by NORC under Contract No. HSSP2337010T/OS33547.) … A case study in connecting stakeholders. J Healthc Inf Manag. 2010;24(1):25-30.
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
    June 01, 2018 - Pairs of investigators independently determined study eligibility and resolved disagreements through … Overall summary RoB assessments for each study were classified as low, moderate, or high based on a … limitations (study design, number of studies, study size, and overall RoB [low, moderate, high, or … Study Design • Observational studies predominated for long term chronic disease outcomes. … findings and to study heterogeneity.
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
    May 01, 2014 - All study data will be verified for accuracy and completeness by a second team member. … Each study evaluated will be dual-reviewed for quality by two team members. … The chronic fatigue syndrome: a comprehensive approach to its definition and study. … International Chronic Fatigue Syndrome Study Group. Ann Intern Med. 1994;121(12). … Chronic fatigue syndrome--a clinically empirical approach to its definition and study.
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
    April 01, 2016 - However, we identified a Tier 3 study comparing electroconvulsive therapy (ECT) to cognitive behavior … ................................................................................................ 2 StudyStudy Selection Using the same inclusion and exclusion criteria as the original systematic review ( … However, we identified a Tier 3 study comparing ECT to CBT augmentation, and antidepressants alone, … RESULTS: Of the 116 patients, 75% (n = 87) completed the study.
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
    April 01, 2012 - to one what was included in this study. … For example the study “Fortune B et al. … program study. … that they had glaucoma but identified through the study. … I believe this study should be included.
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
    April 25, 2013 - The study by Barst et al. was included as extension study of the RCT by Rubin et al., 1990. … as primary a combination therapy study. … The Channick study should be combined with the Rubin study in the plot, but not the Barst study. … The study by Barst et al. was included as extension study of the RCT by Rubin et al., 1990. … High BNP, SSC) needs further study.
  12. Gout Executive-2016 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
    January 01, 2016 - In a 2013 study that analyzed data from several national surveys administered from 2002 to 2008, the … Finally, failure to report important study design details in publications is a further limitation. … A study among four laboratories. Arthritis Rheum. 1986 Jun;29(6):770-4. PMID: 3718565. 12. … Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study. … The validation of a diagnostic rule for gout without joint fluid analysis: a prospective study.
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
    April 01, 2013 - No study clearly was designed using an effectiveness framework, though details on methods were fairly … Mortality and long- term hepatic comp- lications A large VA hospital study that controlled well … Preliminary study of two antiviral agents for hepatitis C genotype 1. … Framework for Considering Study Designs for Future Research Needs. … , or Who Received DAA Treatment in a Tibotec- Sponsored Phase I Study.
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
    February 10, 2016 - In  their  seminal  study,   Wennberg  and  Gittlesohn  found  the  rate  of  tonsillectomy  varied   … Furthermore,  this  study  included  only  randomized  controlled  trials  (RCTs).     …  design.26  Two   investigators  will  assess  each  included  study  independently.   … data;;  that  is,  they  describe  only  between-­study  and  not  between-­patient  variation.   … A  population-­based  study  of  acute  care   revisits  following  tonsillectomy.  
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
    November 01, 2012 - We assessed the quality of each study based on predefined criteria. … No study evaluated the diagnostic accuracy of FibroSpect II for cirrhosis. … One study reported an AUROC of 0.69 (95% CI 0.69 to 0.74). … No study reported the AUROC for the Lok Index for fibrosis. … No study compared effects of screening with not screening pregnant women.
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
    November 24, 2014 - Risk of bias as a domain for strength of evidence is now referred to as “study limitations.” … Studies reviewed over the study period were well done. Thank you for your comment. … The study by Lorente et al is referenced in the text but not included in Table 7. … We think this covers the current future research needs for study design on this topic. … and other measures of illness for each included study.
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
    December 20, 2011 - origin, study design and sample size. … The PROBE-HF study. J Card Fail 2009;15(5):377-84. 7. Zuber M. … Was the outcome absent at the beginning of the study? 7. … Was the length of the study long enough for the outcome to occur? 8. … Study Attrition 2.
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
    July 01, 2012 - At the title and abstract triage phase, we did not exclude any study based solely on study design if … Mortality was often the focus in studies of hospitals and was also the primary outcome in one study … One study found that low-quality surgeons leave practice (considered a positive action). … Mode and tone of message: One study found that mode (email vs. … • Include a systematic approach to the study of harms/ unintended consequences.
  19. Untitled (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
    February 17, 2016 - The main differences relate to dropping Key Questions related to placebo (no prophylaxis) study arms … design •   Randomized controlled trials (any study size) (KQ 1-6) •   Nonrandomized comparative … observational studies (N ≥750 total per study) (KQ 1-4, 6) Timing •   Any duration of follow-up … Data Extraction and Data Management: Each study will be extracted by one methodologist. … , results, and study quality.
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_executive.pdf
    February 01, 2013 - For a single study with precise results, we graded it as low. … Having a study design less rigorous than a controlled trial did not drive our decision to drop a study … A third study found mixed results.33 One study found evidence of benefit for the intervention arm on … The study authors typically evaluated short-term outcomes. … Support for Students Exposed to Trauma: a Pilot Study.

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