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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
    December 01, 2014 - Study Selection We used the same study selection criteria as in the 2008 report. … The data extracted included study, patient, tumor, and intervention characteristics and predefined … To be considered as having high risk of bias, the study must have met at least one of the following … However, neither study compared RP with active surveillance. … Furthermore, in the PIVOT study, the median survival was assumed to be 15 years in the original study
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
    December 17, 2013 - Specific suggestions added clarity to the included interventions and the timing of study followup. … Study inclusion criteria Category Criteria for Inclusion Study Enrollment Studies that enroll adults … Study Quality All studies meeting inclusion criteria will be screened for eligibility. … One investigator will abstract relevant study, population demographic, and outcomes data. … For KQ2, we will also abstract study aims and study findings.
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
    December 14, 2017 - TEP Reviewer #2 Executive Summary This study is not conclusive. … Study characteristics are poorly defined-large number of studies and inter-study variability may be … TEP Reviewer #2 Results This study is much higher quality than Mara study, also rated as Fair!. … Hence we considered this trial to be a ‘fair’ quality study. … is even further weakened from this already weak study.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
    January 15, 2015 - Data Extraction and Management Each study will be extracted by one experienced methodologist. … Any quality issues pertinent to specific outcomes within a study will be noted and applied to those … ; and angioplasty single group studies), then by Key Question and outcome, within each study design … Clinical study design, nonclinical testing, and regulatory considerations for appropriate use of this … Essai Multicentrique Medicaments vs Angioplastie (EMMA) Study Group. Hypertension.
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
    June 01, 2016 - STUDY DESIGN AND OUTCOME MEASURES The study design was a double-blind, multisite, randomized controlled … or computed tomography, and had moderate-to-severe leg pain and dis- ability were eligible for the study … , washout of in- flammatory mediators from the epidural space, and other fac- tors present in both study … groups, including contact with study personnel and receipt of lidocaine. »» The study did not include … tions, as the choice of injection approach was left to the discretion of the physician. »» The study
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
    October 27, 2017 - Given the timeline and resources, we will not contact study authors for additional data. … Overall study quality will be assessed as follows: • Good (low risk of bias). … of the Renfrew/Paisley study. … The Framingham Study. Stroke. 1996 Oct;27(10):1760-4. PMID: 8841325. 11. … PICOTS and Inclusion and exclusion criteria – Study Design Study design exclusions originally
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
    August 01, 2013 - The mean age of study participants ranged from 53 to 81 years. … Study followup duration ranged from 1 to 12 years. … The mean age of study participants ranged from 65 to 80 years. … Study followup duration ranged from 1 to 12 years. … up of the Renfrew/Paisley study.
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
    August 01, 2012 - • Study withdrawals and time to withdrawal because of AEs. … When there were multiple reports of the same study, we referenced the primary or most relevant study … Results Description of Included Studies The searches identified 9,411 unique study reports. … bIncludes 1 cohort study and 1 nRCT. cIncludes 1 nRCT. Note: n = 125. … The NIMH-CATIE Schizophrenia Study: what did we learn? Am J Psychiatry. 2011;168(8):770-5.
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
    November 01, 2013 - Study Selection For KQs 1, 2, and 7, the only excluded study design was the case report. … Table A shows study selection criteria. … Results from the 19 Breathing Not Properly Multinational Study. … Results from the Breathing Not Properly Multinational Study. … Study. J Am Coll Cardiol. 2010;56(25):2090-100. 170.
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
    April 01, 2012 - applied a different reference standard to a subset of participants enrolled in the study. … KQ6 We did not identify any study addressing the harms associated with screening for OAG. … The risk of bias of diagnostic study designs is an additional concern. … : the Tajimi Study. … Population and high-risk group screening for glaucoma: the Los Angeles Latino Eye Study.
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
    June 01, 2012 - Analytic Framework Given the heterogeneity in key aspects of study design across the four Key Questions … Next, two researchers independently reviewed study abstracts to determine whether the study should … The third study assessed the effectiveness of a centralized public information system implemented in … A single study tested a strategy for augmenting scarce resources during an MCE. … ) • Hospital-based case managers to ensure care coordination Decontamination (1 study) • Strategies
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/health-information-exchange_executive.pdf
    December 01, 2015 - lowering our confidence in the study results). … Outcomes assessment of the regional health information exchange: a five-year follow-up study. … A case study. Comput Methods Programs Biomed. 2008;91(2):175-81. PMID: 18514363. 34. … Case Study Report. (Prepared by NORC under Contract No. HSSP2337010T/OS33547.) … A case study in connecting stakeholders. J Healthc Inf Manag. 2010;24(1):25-30.
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
    May 01, 2014 - All study data will be verified for accuracy and completeness by a second team member. … Each study evaluated will be dual-reviewed for quality by two team members. … The chronic fatigue syndrome: a comprehensive approach to its definition and study. … International Chronic Fatigue Syndrome Study Group. Ann Intern Med. 1994;121(12). … Chronic fatigue syndrome--a clinically empirical approach to its definition and study.
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
    June 01, 2018 - Pairs of investigators independently determined study eligibility and resolved disagreements through … Overall summary RoB assessments for each study were classified as low, moderate, or high based on a … limitations (study design, number of studies, study size, and overall RoB [low, moderate, high, or … Study Design • Observational studies predominated for long term chronic disease outcomes. … findings and to study heterogeneity.
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
    April 01, 2016 - However, we identified a Tier 3 study comparing electroconvulsive therapy (ECT) to cognitive behavior … ................................................................................................ 2 StudyStudy Selection Using the same inclusion and exclusion criteria as the original systematic review ( … However, we identified a Tier 3 study comparing ECT to CBT augmentation, and antidepressants alone, … RESULTS: Of the 116 patients, 75% (n = 87) completed the study.
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
    April 01, 2012 - to one what was included in this study. … For example the study “Fortune B et al. … program study. … that they had glaucoma but identified through the study. … I believe this study should be included.
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/adhd_executive.pdf
    October 01, 2011 - Study authors were contacted via email for missing outcome or design data. … SOE: Insufficient Only one study of GXR monotherapy is available. … ADHD comorbidity findings from the MTA study: comparing comorbid subgroups. … Jensen PS, Arnold LE, Swanson JM, et al. 3­year follow­up of the NIMH MTA study. … A 10­year follow­up study. Pediatrics. 2009;124(1):71­8. 87.
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
    April 25, 2013 - The study by Barst et al. was included as extension study of the RCT by Rubin et al., 1990. … as primary a combination therapy study. … The Channick study should be combined with the Rubin study in the plot, but not the Barst study. … The study by Barst et al. was included as extension study of the RCT by Rubin et al., 1990. … High BNP, SSC) needs further study.
  19. Gout Executive-2016 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
    January 01, 2016 - In a 2013 study that analyzed data from several national surveys administered from 2002 to 2008, the … Finally, failure to report important study design details in publications is a further limitation. … A study among four laboratories. Arthritis Rheum. 1986 Jun;29(6):770-4. PMID: 3718565. 12. … Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study. … The validation of a diagnostic rule for gout without joint fluid analysis: a prospective study.
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
    April 01, 2013 - No study clearly was designed using an effectiveness framework, though details on methods were fairly … Mortality and long- term hepatic comp- lications A large VA hospital study that controlled well … Preliminary study of two antiviral agents for hepatitis C genotype 1. … Framework for Considering Study Designs for Future Research Needs. … , or Who Received DAA Treatment in a Tibotec- Sponsored Phase I Study.

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