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effectivehealthcare-admin.ahrq.gov/products/obesity-research-methods/systematic-review
November 01, 2019 - of data dictionaries, reporting standards on data linkage, long-term obesity-related outcomes, and study … experimental studies (randomized or non-randomized controlled trials), and 20 (7 percent) had other study … Study Design and Methods: Natural experiment studies most commonly used cross-sectional comparisons … having a weak rating for handling of withdrawals and dropouts, 42 percent having a weak rating for study … Experimental studies were rated as “strong” (low risk of bias) in study design, control of confounding
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effectivehealthcare-admin.ahrq.gov/sites/default/files/assessing-quality.ppt
January 01, 2010 - to the Body of Evidence
Quality (systematic error and inferential error, type of study)
Size of study … to the Body of Evidence
The quality or internal validity of a study (i.e., limitations of study design … Study design — sources of bias may vary by design
Study conduct — poor study conduct and discrepancy … Other considerations include study conduct and discrepancies between study design and study conduct. … study design.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
June 02, 2011 - can be thought of as assessing the risk that the study results
reflect bias in study design or execution … who remain in the study. … x x
Did the strategy for recruiting participants into the study differ across study
groups? … x x x x x
Did variation from the study protocol compromise the conclusions of the
study? … design
Study Design Quality Considerations
RCTs On study conduct:
Are definitions of reported
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effectivehealthcare-admin.ahrq.gov/sites/default/files/ebc-challenge-case-130621.pdf
June 01, 2013 - The Evidence-Based Care Challenge: A Case Study
The Evidence-Based Care Challenge:
A Case … Study
Prepared for:
Agency for Healthcare Research and Quality
U.S. … The Evidence-Based Care Challenge: A Case Study. … Organization of This Case Study
This case study is organized around the main phases of activity within … Knowledge gained can be shared internally or more broadly, as is
the intent of this case study.
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effectivehealthcare-admin.ahrq.gov/health-topics/understanding-medical-research
March 18, 2014 - Description
It seems to happen almost every day - you hear about the results of a new medical research study … Sometimes the results of one study seem to disagree with the results of another study. … Some questions that can help you evaluate health information include:
Was the study in animals … Does the study include people like you?
How big was the study?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
March 01, 2013 - Since each study is conducted under different conditions and populations, study-specific
effect sizes … Study 2: 1 vs. 2
12. … ;
run;
/* Fixed effects model */
proc genmod data=UI_imp;
class study trt;
model R/N = Study … Karram, 200939,40 This study, that is, the
VENUS study
enrolled patients
aged>=18 years with
OAB … Trospium Study Group.
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effectivehealthcare-admin.ahrq.gov/products/quality-rating/research
November 01, 2017 - Home
Evidence Reports
A Process for Robust and Transparent Rating of Study … SHARE:
A Process for Robust and Transparent Rating of Study … our findings are preliminary, and no definite conclusions could and should be drawn from this pilot study … A study with large variations in quality assessment may fundamentally be very different from one that … Project Timeline
A Process for Robust and Transparent Rating of Study Quality: Phase 1
May 4, 2010
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-bias-individual-studies/methods
October 01, 2019 - under study. … who remain in the study. … for each included outcome of the individual study, considering study conduct, and categorize as low, … differ across study groups?
… is to categorize the study design.
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effectivehealthcare-admin.ahrq.gov/products/accelerated-partial-breast-irradiation/protocol
October 01, 2021 - field study/ 42 in vivo study/ 43 exp panel study/ 44 exp Pilot Projects/ 45 exp pilot study/ 46 exp … study" or "case referent study" or "case compeer study" or "case comparison study" or "matched case … study" or "case referent study" or "case compeer study" or "case comparison study" or "matched case … field study/ 43 in vivo study/ 44 exp panel study/ 45 exp Pilot Projects/ 46 exp pilot study/ 47 exp … study” or “case referent study” or “case compeer study” or “case comparison study” or “matched case
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - A potential advantage of this type of study is that long-
term benefits, tolerability, and harms can … This
assessment will focus particularly on issues of the natural history of the condition under study … Different study designs may be
optimal for different types of review questions, and study designs must … Heart Protection Study Collaborative Group. … Although the
study did not compare one triptan with another, the study provided data that a particular
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effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
June 01, 2010 - A potential advantage of this type of study is that long-
term benefits, tolerability, and harms can … This
assessment will focus particularly on issues of the natural history of the condition under study … Different study designs may be
optimal for different types of review questions, and study designs must … Heart Protection Study Collaborative Group. … Although the
study did not compare one triptan with another, the study provided data that a particular
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-bias/methods
December 01, 2019 - Judging the overall quality of an individual study involves examining the size of the study, the direction … The evaluation of study features that might influence the relative importance of a particular study has … study. … issues of reporting by contacting study authors. … Judging the overall quality of an individual study involves examining the size of the study, the direction
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-appendix-a.pdf
August 31, 2023 - * adj3 study) or (control* adj3 trial) or (randomized adj3 study) or
(randomized adj3 trial) or (randomised … adj3 study) or (randomised adj3 trial) or
"pragmatic clinical trial" or (random* adj1 allocat*) or … "quasi experimental analysis" or "quasiexperimental study" or "quasiexperimental
analysis" or "case … control study" or "case base study" or "case referrent study" or
"case referent study" or "case referent … study" or "case compeer study" or "case
comparison study" or "matched case control" or "before and
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
August 09, 2021 - study/
41 exp field study/
42 in vivo study/
43 exp panel study/
44 exp Pilot Projects/
45 exp … pilot study/
46 exp prevention study/
47 exp replication study/
48 exp theoretical study/
49 exp … "case referent study" or "case referent study" or "case compeer
study" or "case comparison study" or … study/
42 exp field study/
43 in vivo study/
44 exp panel study/
45 exp Pilot Projects/
46 exp … pilot study/
47 exp prevention study/
48 exp replication study/
49 exp theoretical study/
50 exp
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease-appendix-a.pdf
August 31, 2023 - /
21 exp quasi experimental study/
22 exp case-control studies/
23
((control* adj3 study) or … (control* adj3 trial) or (randomized adj3 study) or (randomized
adj3 trial) or (randomised adj3 study … " or "prospective survey" or "prospective analysis" or prospectiv* or
"quasi experimental study" or … control study" or "case base study" or "case referrent
study" or "case referent study" or "case referent … study" or "case compeer study" or "case
comparison study" or "matched case control" or "before and
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-bias/methods
August 01, 2019 - Study Designs or Study Characteristics
Due to time, budget, or resource constraints as well as concerns … of individual study), language of publication, study size, or reporting of relevant data. … the study in the SR. … For unpublished studies, manufacturers are asked to provide a summary that includes study number, study … Because the study is registered at the beginning of the study, the intended primary outcome measures,
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - There was no significant difference in risk of
all-cause mortality in any study. … Hydroxychloroquine and tocilizumab therapy in
COVID-19 patients-An observational study. … Documents reporting on the same study were consolidated into one study record. … A-3
The following data were abstracted:
• Study identifier (author) and publication year
• Study … For a study to be rated “overall” as low risk, the study must be rated as low risk on both
items.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/appendix-table-B-1-observational-studies.xlsx
March 20, 2021 - Author Publication Year Title PMID Publication Status at Time of Report Publication Link/URL Country Study … Data obtained as part of the study Any employee of SpaceX None Ab+ Negative serology Range: 18–71 years … Healthcare workers Healthcare workers at Strasbourg University Hospital Data obtained as part of the study … facility residents Residents and staff at two nursing homes in London Data obtained as part of the study … a This study did not provide patient-level data, but used modeling to estimate protection.
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effectivehealthcare-admin.ahrq.gov/products/transparency-mental-health/research-protocol
January 01, 2019 - reported, retention, study conduct, and other details of study design in the peer reviewed literature … Your study [xxx, has been included/is eligible for inclusion] in this review. … Is the study listed elsewhere on another clinical trials registry? … [If the study results are not listed in any clinical trials registry] Did you attempt to list your study … Is the study ongoing? If yes, when is the anticipated date of completion?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
January 01, 2012 - Study design in the SR: Are they relevant to proposed study? … Study design: Compare study designs, sources of bias of included studies, feasibility of study
designs … Comment:
A-2
Were the Results Similar From Study to Study?
What is Best? … PICO of
the proposed new study. … NA Unclear (8 studies included with 743 patients)
Were the results similar
from study to study?