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3701. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
      November 24, 2014 - While retrospective studies were included in this comparative effectiveness review, only studies with … Again, given that there were so few studies, more detail about the studies, the baseline characteristics … This level of granularity was not given in the studies included, as none of the included studies related … Studies addressing once daily dosing of aminoglycosides were not included because studies were required … Six studies (4 clinical trials and two cohort studies met inclusion criteria, but only one study, with

3702. Disposition of Comments Report for Comparative Effectiveness Review No. 137 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_disposition-comments.pdf
      August 06, 2014 - We restricted to studies in children ages 0-12 and studies published from 2000 to the present. … , large multi-site observational studies)? … were follow-ups to studies evaluated in the 2011 review. … report followup data from studies in the prior review. … comorbid conditions, not all studies in the review.

3703. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
      November 01, 2013 - EPCs can consider studies to be consistent when the CIs of individual studies overlap a summary effect … reporting bias for such studies. … in question; these studies are of unequal size; smaller and larger studies do not differ substantially … the smaller studies. … in evidence base Consider the number of studies and total sample size across studies assessed at risk

3704. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
      June 01, 2011 - Low or This conclusion is based on evidence from 77 studies (70 (DRI vs. … There were no relevant studies evaluating direct renin inhibitors. e. … There were only two studies comparing direct renin treatment adherence? … Angioedema: Low Although several studies collected data on angioedema, the (ACEI vs. … Only nine studies compared ACEIs and ARBs for periods longer than 1 year.

3705. Archived: Final Research Plan: Breast Cancer: Screening | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan97/breast-cancer-screening-january-2016
      July 17, 2014 - Harms KQs 5, 6: RCTs, prospective and retrospective cohort studies, case-control studies, cross-sectional … studies, systematic reviews, meta-analyses, and modeling studies; others considered. … Studies of women in other countries; older studies (see search dates). … Harms (KQs 5, 6): Studies published between 2008 and February 2014 and updates of earlier studies. … KQs 7–10: Studies published between January 2000 and July 2014.

3706. Methods-Guidance-Reporting-Bias Methods (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
      November 01, 2013 - , with observational studies representing 17 percent of all studies registered in ClinicalTrials.gov … studies,37-39 although some have suggested that requirements to register observational studies might … and unpublished studies submitted by manufacturers to identify any remaining unpublished studies or … , studies of complementary and alternative interventions, and non-English language studies. … • Arranges outcomes in columns and studies in rows for all included studies.

3707. Disposition of Comments Report for Otitis Media With Effusion (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_disposition-comments.pdf
      May 04, 2013 - We recognize that by excluding single arm studies, we may have eliminated studies that examined important … Appendix for Included studies. … The proper terminology would be “tubes used in included studies,” since in most of the studies (in the … One of the studies was an RCT,29 and the other two were nonrandomized controlled studies.30, 31 The … The only other possibility is the reports of the studies are flawed that he studies themselves are not

3708. Disposition of Comments for CER 157 Appendicitis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
      December 14, 2015 - often referred to as “case-control” studies, but we prefer to reserve this term for studies of etiology … For example, the decision to limit studies from the discussion for multivariate scores (to 5 studies … studies and modify our conclusions based on the assessment of the risk of bias of the studies. … This suggest that imaging studies are made on a different population than the clinical studies. … TEP Reviewer #2 Results The decision to limit Table #13 to studies with five or more studies seems

3709. renal-update-2015-150115 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
      January 15, 2015 - The large majority of the evaluated studies were single-group studies (without a comparison intervention … This decision will be re-evaluated if studies based on registry datasets are available. … studies. … (follow-up or followup).tw. 26. exp Case-Control Studies/ 27. … (case adj20 control).tw. 28. exp Longitudinal Studies/ 29. longitudinal.tw. 30. exp Cohort Studies

3710. Nephropathy-Contrast-Induced Executive-2016 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
      January 01, 2016 - We also reviewed applicable observational studies. … ), cardiovascular outcomes (7 studies), mortality (8 studies), adverse events (12 studies), or image … and diagnostic quality (2 studies). … Because we excluded studies that did not report data on CIN, we excluded studies that reported only … Assessing Risk of Bias in Included Studies.

3711. Disposition of Comments for Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
      August 27, 2012 - in those areas (i.e., why were the studies rated as poor?) … RCTs and we assess quality of studies by study design. … , but no relevant studies met our inclusion criteria. … We included studies of any intervention. … Given the absence of good studies and scarcity of fair studies, the report concludes that the available

3712. Disposition of Comments Report for CER 134 Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
      May 13, 2014 - Nonetheless, we don't have studies in primary care settings or naturalistic studies. Thank you. … Naltrexone was very consisted in exhibiting a small effect across these studies, while acamprosate studies … Methods probably varied among studies. … be replicated by consequent unbiased studies. … Peer Reviewer #2 Table of Excluded Studies 1. Table of excluded studies.

3713. Supplemental Project To Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
      June 01, 2017 - We assess whether the new studies fall within the range of the similar studies from the original review … Studies Included in the Original Review, With a Registry Record Only six studies (in seven records) … Relevant Studies Identified via Registry Searches and Not Found in Original Review Twenty studies … Studies Identified via Registry Searches and Not Found in Original Review Studies Containing Results … Excluded Studies Appendix E.

3714. Gout Executive-2016 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
      January 01, 2016 - However, if no such studies could be identified for a diagnostic test of interest, studies were also … Seventeen studies answer Key Question 1, and two studies answer Key Question 2. … Description of Included Studies We identified 15 original studies that met our inclusion criteria for … no studies that limited inclusion only to patients presenting with a first attack, and few studies … studies.

3715. Psn-Pdf (pdf file)
      psnet.ahrq.gov/node/42067/psn-pdf
      March 18, 2013 - However, this systematic review identifies an underlying flaw inherent in studies of medication administration … For example, only 6 of 16 included studies considered administration of a drug at the wrong time to … As delayed drug administration is relatively common, studies that did not include such wrong-time errors … Prior studies have also raised concern that variations in the definition of medication errors can affect … rates, and medication error measurement standards have been developed for medication reconciliation studies

3716. Nontraditional Risk Factors in Cardiovascular Disease Risk Assessment: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
      July 17, 2018 - The addition of the ABI (10 studies), hsCRP level (25 studies), or CAC score (19 studies) can improve … ) included for KQ2 8 Articles (8 studies) included for KQ3 5 Articles (4 studies) included for KQ4 … Published coefficient model studies are risk prediction studies evaluating the added prognostic value … Ten studies evalu- ated the ABI, 25 studies evaluated hsCRP level, and 19 studies evaluated CAC score … (9 studies), or CAC score (8 studies) can im- prove agreement between predicted and observed events

3717. Psn-Pdf (pdf file)
      psnet.ahrq.gov/node/36358/psn-pdf
      June 13, 2011 - Case studies on medication reconciliation. June 13, 2011 Crawford AG; Sciamanna CN. … https://psnet.ahrq.gov/issue/case-studies-medication-reconciliation The journal provides an editorial … and several case studies on medication reconciliation from a variety of health care environments. … https://psnet.ahrq.gov/issue/case-studies-medication-reconciliation https://psnet.ahrq.gov/primer/medication-reconciliation

3718. Disposition of Comments for Self-Measured Blood Pressure Monitoring: Comparative Effectiveness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
      January 01, 2012 - The Community Task Force omits C grade studies in their summary statements. … Studies used a variety of different definitions of adherence. … We added the need to conduct studies in children to the research recommendations. … in any of the short-term studies). … Unfortunately, the additional support differed for each of these 5 studies.

3719. Final Research Plan: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/abdominal-aortic-aneurysm-screening
      November 30, 2017 - KQs 1, 4: Randomized, controlled trials KQs 2, 3: Randomized, controlled trials; large cohort studies … (sample size >1,000) KQ 5: Randomized, controlled trials; large cohort studies (sample size >1,000 … ); vascular surgery registries KQs 1, 4: Case-control, cross-sectional, and cohort studies; editorials … , letters, and opinions; cost studies KQs 2, 3: Case-control and cross-sectional studies; editorials … , letters, and opinions; cost studies Countries Studies conducted in countries categorized

3720. Final Research Plan: Hepatitis B Virus Infection in Pregnant Women: Screening | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-in-pregnant-women-screening
      November 09, 2017 - Study Design KQ 1: Randomized or clinical controlled trials, systematic reviews, before-after studies … , observational cohort studies, and ecologic studies with a historical or geographic comparator KQs … 2–4: All of the above plus cohort studies, case series, and registry data KQs 3, 4: Trials examining … Poor-quality studies Publication Dates 1986 to the present Studies conducted prior to the … Several comments suggested including studies examining the benefits and harms of specific treatment or