-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
January 01, 2007 - studies). … year (2
studies). … all eight studies. … ), headache (21 studies), dizziness (18 studies), fatigue (10
studies), upper respiratory infection … (6 studies), and nausea (6 studies).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - of
these studies were applicable to KQ 3,16-18 and one was
applicable to KQ 2.19 Of the 94 studies … Of these 94 studies, 78 studies included sufficient
data to estimate the sensitivity and specificity … , two studies of CMR, and four studies of SPECT that reported these
predictors … 2) ECHO (6 studies), (3) SPECT (3 studies), (4) CMR (2 studies), and (5)
coronary CTA (4 studies) … noncomparative
studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
December 01, 2010 - Five of six testers agreed on two studies, four agreed on six studies, three agreed on two
studies, … studies, and cohort studies). … Five of six testers agreed on two studies, four agreed on six studies,
three agreed on two studies, … the studies. … studies.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/xBhJwGtUHqmEvPg_gKk4nw
January 01, 2001 - KQ1 Direct Grade
assignment/
health
equity
RCTs, controlled
trials, and
observational
studies … Studies
should be well
designed§ with low
risk for bias using
robust
contemporaneous
comparison … groups
Children and
adolescents
aged 5 to 17
years; studies
should be
representative
of the … Studies
should be well
designed§ with low
risk for bias using
robust
contemporaneous
comparison … KQ1 Direct Grade
assignment/
health
equity
RCTs, controlled
trials, and
observational
studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
October 01, 2016 - Studies in
the original report deemed eligible for pooling with newly
identified studies were included … Risk of bias among observational studies
was assessed using questions relevant for prospective
studies … Prospective observational studies
and biomarker studies reported inconsistent associations
between … Among studies
reporting on the same outcomes, results were often
inconsistent across studies. … Studies that labeled themselves
as studies of DHA alone often included some amount
of EPA as well as
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
October 12, 2016 - (Comments pertain to
the maternal studies more than the child studies.) … Studies of n-3 FA alone were included as
were studies of n-3s plus n-6s. … The list of studies is comprehensive
and doesn't include studies that should have been
excluded. … to the studies we could
include. … studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
October 01, 2010 - Decision To Combine Studies
The decision to combine studies to produce an overall estimate should depend … Clinical and methodological diversity among studies always exists even if a group of studies
meet all … When the
sizes of the included studies are small, it would take a substantial number of studies to … Combining studies of mixed designs. … excluding such studies.
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
March 01, 2014 - Overall, we included 121 studies represented
by these 115 publications: 78 studies were relevant to … Nineteen studies in
KQ 1 (23%) and 3 studies in KQ 2 (6%) included children. … Seven studies were RCTs, and the remaining
71 were observational studies. … Thirty-three of the 48 studies were
parallel-group RCTs, and 12 were randomized crossover
studies. … studies of 59 individual agents.
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
October 01, 2010 - Decision To Combine Studies
The decision to combine studies to produce an overall estimate should depend … Clinical and methodological diversity among studies always exists even if a group of studies
meet all … When the
sizes of the included studies are small, it would take a substantial number of studies to … Combining studies of mixed designs. … excluding such studies.
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - Quality Assessment of Individual Studies
We evaluated the quality of individual studies by using
the … Six studies (four RCTs, two observational studies)
reported variations in the treatment effectiveness … Subgroups reported included age (three studies), symptom
class (three studies), renal failure (two studies … ), arterial
outflow/runoff (two studies), anatomic factors (two
studies), type of vein graft (two studies … IC-CLI-Obs (3 studies, 563,935 patients)
IC-CLI-RCT (2 studies, 130 patients)
Inconclusive evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - Observational Studies
Observational studies are almost always necessary to assess harms adequately … Other observational studies. … Two studies found that industry-
funded studies tended to report more favorable outcomes than did studies … types of studies. … Review
Studies meet certain study design definitions (e.g., cohort and case-control studies)
Studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - Observational Studies
Observational studies are almost always necessary to assess harms adequately … Other observational studies. … Two studies found that industry-
funded studies tended to report more favorable outcomes than did studies … types of studies. … Review
Studies meet certain study design definitions (e.g., cohort and case-control studies)
Studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
July 01, 2011 - The two studies of cardiovascular mortality did not
have consistent findings, and the two studies of … Overall, the studies
were clinically heterogeneous, small, and of quality B
(three studies) or C (two … studies). … Treatments
• Only 3 of the 190 studies of treatments reported
clinical outcomes; comparative studies … Only 3 of 7 studies found increased
number of hours of CPAP use; only 1 of 3 studies found
persistent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - Observational Studies, Intake
Seven studies evaluated total n-3 FA intake. … studies), CHD
death (3 of 7 studies), MI (1 of 2 studies), incident CHF (1
of 5 studies), and AFib … (1 of 3 studies). … ), CVD (3 studies), MACE (2 studies),
hemorrhagic and ischemic stroke (2 studies each), AFib (1
study … total stroke (2 studies each), MACE (2
studies), all-cause death (2 studies), or AFib, SCD, incident
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-nonpregnant-adults-and-adolescents-june-2016
June 07, 2016 - Some studies may have addressed more than one Key Question. A total of 9 studies were included. … 4 observational studies of MSM and HIV-positive males
No studies of screening effectiveness … No studies
No studies
No studies
No studies
No studies
No studies
Key question 3: … Fair
Key question 4: Screening harms e
No studies
No studies
No studies
No studies
No … studies
No studies
No studies
Abbreviations: MSM, men who have sex with men; RPR, rapid
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
January 10, 2017 - Excluded were poor-quality studies; studies of prepubertal girls, men, women without the potential for … Four studies (1 cohort study 19 and 3 case-control studies 17 , 20 , 22 ) reported on dose of folic … Five studies (1 cohort study 18 and 4 case-control studies 6 , 7 , 20 , 21 ) reported on timing of folic … Early studies (1 trial, cohort and case-control studies) provided consistent evidence of benefit. … a Studies are listed by data source first (multistate case-control studies first, single/2-state case-control
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
August 01, 2012 - epidemiologic studies—STrengthening
the Reporting of OBservational studies in Epidemiology
(STROBE … two quality A studies, a low rating
involves quality B or quality C studies, and an insufficient
rating … Few
studies were designed a priori as studies of diagnostic-
test performance with an adequately powered … The eight reviewed studies of patients with MM were
mostly retrospective cohort studies, and only three … or of
cohort studies in this area.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/nfP93-Hva3bvxkvkBStTgm
Harms: Randomized,
controlled trials; cohort
studies; case-control
studies; diagnostic
accuracy … studies; large
case series; and
systematic reviews and
meta-analyses (of
included study designs) … ,
comparative
effectiveness studies of
various screening
timepoints, modeling
studies
multiple … ; case-control
studies; diagnostic
accuracy studies; large
case series; comparative
effectiveness … studies;
modeling studies; and
systematic reviews and
meta-analyses (of
included study designs)
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/TzddJozNQQZYmTohr64wMz
June 07, 2016 - ) reviewed
4 Reviewed for KQ1
(observational studies)
4 Studies included for KQ1 0 Studies included … 4 observational
studies of MSM
and HIV-positive
males
No studies of
screening
effectiveness
No studies … Fair
Key question 2:
Effectiveness of risk
assessmentc
No studies No studies No studies No studies … No studies No studies No
studies
Key question 3:
Screening accuracyd
Included studies
conducted in … Fair
Key question 4:
Screening harmse
No studies No studies No studies No studies No studies No studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - Little disagreement exists across
studies. … Underlying studies may report
conflicting results. … The majority of the patients in these studies
were men, and the reviewed studies specifically excluded … We were not able to conduct meaningful
subgroup analyses stratifying older versus newer studies
(studies … studies.