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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
    January 01, 2007 - studies). … year (2 studies). … all eight studies. … ), headache (21 studies), dizziness (18 studies), fatigue (10 studies), upper respiratory infection … (6 studies), and nausea (6 studies).
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
    June 01, 2012 - of these studies were applicable to KQ 3,16-18 and one was applicable to KQ 2.19 Of the 94 studies … Of these 94 studies, 78 studies included sufficient data to estimate the sensitivity and specificity … , two studies of CMR, and four studies of SPECT that reported these predictors … 2) ECHO (6 studies), (3) SPECT (3 studies), (4) CMR (2 studies), and (5) coronary CTA (4 studies) … noncomparative studies.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
    December 01, 2010 - Five of six testers agreed on two studies, four agreed on six studies, three agreed on two studies, … studies, and cohort studies). … Five of six testers agreed on two studies, four agreed on six studies, three agreed on two studies, … the studies. … studies.
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/xBhJwGtUHqmEvPg_gKk4nw
    January 01, 2001 - KQ1 Direct Grade assignment/ health equity RCTs, controlled trials, and observational studiesStudies should be well designed§ with low risk for bias using robust contemporaneous comparison … groups Children and adolescents aged 5 to 17 years; studies should be representative of the … Studies should be well designed§ with low risk for bias using robust contemporaneous comparison … KQ1 Direct Grade assignment/ health equity RCTs, controlled trials, and observational studies
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
    October 01, 2016 - Studies in the original report deemed eligible for pooling with newly identified studies were included … Risk of bias among observational studies was assessed using questions relevant for prospective studies … Prospective observational studies and biomarker studies reported inconsistent associations between … Among studies reporting on the same outcomes, results were often inconsistent across studies. … Studies that labeled themselves as studies of DHA alone often included some amount of EPA as well as
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
    October 12, 2016 - (Comments pertain to the maternal studies more than the child studies.) … Studies of n-3 FA alone were included as were studies of n-3s plus n-6s. … The list of studies is comprehensive and doesn't include studies that should have been excluded. … to the studies we could include. … studies.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - Decision To Combine Studies The decision to combine studies to produce an overall estimate should depend … Clinical and methodological diversity among studies always exists even if a group of studies meet all … When the sizes of the included studies are small, it would take a substantial number of studies to … Combining studies of mixed designs. … excluding such studies. 7.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
    March 01, 2014 - Overall, we included 121 studies represented by these 115 publications: 78 studies were relevant to … Nineteen studies in KQ 1 (23%) and 3 studies in KQ 2 (6%) included children. … Seven studies were RCTs, and the remaining 71 were observational studies. … Thirty-three of the 48 studies were parallel-group RCTs, and 12 were randomized crossover studies. … studies of 59 individual agents.
  9. effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - Decision To Combine Studies The decision to combine studies to produce an overall estimate should depend … Clinical and methodological diversity among studies always exists even if a group of studies meet all … When the sizes of the included studies are small, it would take a substantial number of studies to … Combining studies of mixed designs. … excluding such studies. 7.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
    May 01, 2013 - Quality Assessment of Individual Studies We evaluated the quality of individual studies by using the … Six studies (four RCTs, two observational studies) reported variations in the treatment effectiveness … Subgroups reported included age (three studies), symptom class (three studies), renal failure (two studies … ), arterial outflow/runoff (two studies), anatomic factors (two studies), type of vein graft (two studies … IC-CLI-Obs (3 studies, 563,935 patients) IC-CLI-RCT (2 studies, 130 patients) Inconclusive evidence
  11. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - Observational Studies Observational studies are almost always necessary to assess harms adequately … Other observational studies. … Two studies found that industry- funded studies tended to report more favorable outcomes than did studies … types of studies. … Review Studies meet certain study design definitions (e.g., cohort and case-control studies) Studies
  12. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
    November 01, 2008 - Observational Studies Observational studies are almost always necessary to assess harms adequately … Other observational studies. … Two studies found that industry- funded studies tended to report more favorable outcomes than did studies … types of studies. … Review Studies meet certain study design definitions (e.g., cohort and case-control studies) Studies
  13. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
    July 01, 2011 - The two studies of cardiovascular mortality did not have consistent findings, and the two studies of … Overall, the studies were clinically heterogeneous, small, and of quality B (three studies) or C (two … studies). … Treatments • Only 3 of the 190 studies of treatments reported clinical outcomes; comparative studies … Only 3 of 7 studies found increased number of hours of CPAP use; only 1 of 3 studies found persistent
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
    August 01, 2016 - Observational Studies, Intake Seven studies evaluated total n-3 FA intake. … studies), CHD death (3 of 7 studies), MI (1 of 2 studies), incident CHF (1 of 5 studies), and AFib … (1 of 3 studies). … ), CVD (3 studies), MACE (2 studies), hemorrhagic and ischemic stroke (2 studies each), AFib (1 study … total stroke (2 studies each), MACE (2 studies), all-cause death (2 studies), or AFib, SCD, incident
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-nonpregnant-adults-and-adolescents-june-2016
    June 07, 2016 - Some studies may have addressed more than one Key Question. A total of 9 studies were included. … 4 observational studies of MSM and HIV-positive males No studies of screening effectiveness … No studies No studies No studies No studies No studies No studies Key question 3: … Fair Key question 4: Screening harms e No studies No studies No studies No studies No … studies No studies No studies Abbreviations: MSM, men who have sex with men; RPR, rapid
  16. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
    January 10, 2017 - Excluded were poor-quality studies; studies of prepubertal girls, men, women without the potential for … Four studies (1 cohort study 19 and 3 case-control studies 17 , 20 , 22 ) reported on dose of folic … Five studies (1 cohort study 18 and 4 case-control studies 6 , 7 , 20 , 21 ) reported on timing of folic … Early studies (1 trial, cohort and case-control studies) provided consistent evidence of benefit. … a Studies are listed by data source first (multistate case-control studies first, single/2-state case-control
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - epidemiologic studies—STrengthening the Reporting of OBservational studies in Epidemiology (STROBE … two quality A studies, a low rating involves quality B or quality C studies, and an insufficient rating … Few studies were designed a priori as studies of diagnostic- test performance with an adequately powered … The eight reviewed studies of patients with MM were mostly retrospective cohort studies, and only three … or of cohort studies in this area.
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/nfP93-Hva3bvxkvkBStTgm
    Harms: Randomized, controlled trials; cohort studies; case-control studies; diagnostic accuracy … studies; large case series; and systematic reviews and meta-analyses (of included study designs) … , comparative effectiveness studies of various screening timepoints, modeling studies multiple … ; case-control studies; diagnostic accuracy studies; large case series; comparative effectiveness … studies; modeling studies; and systematic reviews and meta-analyses (of included study designs)
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/TzddJozNQQZYmTohr64wMz
    June 07, 2016 - ) reviewed 4 Reviewed for KQ1 (observational studies) 4 Studies included for KQ1 0 Studies included … 4 observational studies of MSM and HIV-positive males No studies of screening effectiveness No studies … Fair Key question 2: Effectiveness of risk assessmentc No studies No studies No studies No studies … No studies No studies No studies Key question 3: Screening accuracyd Included studies conducted in … Fair Key question 4: Screening harmse No studies No studies No studies No studies No studies No studies
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
    February 01, 2013 - Little disagreement exists across studies. … Underlying studies may report conflicting results. … The majority of the patients in these studies were men, and the reviewed studies specifically excluded … We were not able to conduct meaningful subgroup analyses stratifying older versus newer studies (studiesstudies.