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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
    May 08, 2013 - Regarding the quality of the studies, we agree that there were many studies of poor quality and/or small … Hence, earlier studies will not fair as well as more recent studies provided invesitgators of more … studies. … reported for some studies but unavailable for other studies. … studies resemble pilot studies-further complicating the task.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
    November 01, 2009 - Out of 243 papers, 185 were single-arm retrospective studies, and another 35 studies were prospective … Seven studies (3 percent) focused on a pediatric population; most of the remaining studies reported … Most studies reported patient relevant-clinical outcomes: 151 studies (62 percent) described overall … photon radiation for other cancers (six studies); surgery (three studies). … The remaining 220 studies were single-arm studies (case series or cohort studies); 185/220 were retrospective
  3. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
    September 06, 2016 - 0.90 (57 studies; n = 4378). … For harms of treatment (KQ5), prospective cohort studies and case-control studies were also eligible. … No eligible studies were identified. … , 45 , 58 , 76 less than 5% in 9 studies, 64 , 65 , 77 , 78 , 80 , 82-85 and not reported in 5 studies … TB IGRA test used in US studies higher than threshold used in non-US studies.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-2010_research-protocol.pdf
    January 01, 2010 - ); insurance type/status (9 studies); nutritional status (2 studies); provider and institutional policy … , and maternal age (>15 studies); sleep and fatigue (2 studies); maternal weight, obesity, body mass … index, and height (35 studies); and miscellaneous topics, including studies examining large cohorts … of women with multiple contributing risk factors (>50 studies). … For observational studies (specifically the pre- and post- studies of health systems changes), we will
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_executive.pdf
    November 01, 2012 - These were simple before-after studies or controlled before- after studies (2 of 88) with two group … rates for multiple individual infections.14,35,61 These studies are treated as separate studies, one … Most studies used multiple QI strategies; only 12 studies used a single QI strategy. … Fourteen of the studies adjusted for potential confounders, and the results of these studies appeared … Most studies of QI strategies are effectiveness studies rather than efficacy studies.
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/UCajZVxQEKLCgs59HV7ddE
    November 01, 2008 - Poor- quality studies were excluded. … (Key question 2b) Fecal tests 11 total studies FIT 9 cohort studies of test accuracy Cannot clearly … High- sensitivity guaiac 2 cohort studies of test accuracy 2 comparative studies, 1 using different … Studies (n � 86 498) provided estimates for Magstream (3 studies; n � 37 330 ), OC-Hemodia (3 studies … Flexible sigmoidoscopy 2 retrospective cohort studies, 6 prospective cohort studies 5 studies were
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
    July 01, 2014 - Studies that had serious flaws were rated high risk of bias, studies that met all criteria were low … In this report, direct evidence included studies (trials or observational studies) that compared pregnant … Indirect evidence included studies (trials or observational studies) of pregnant or postpartum women … The majority of the evidence was from observational studies (124 unique studies); we included only … Few studies reported race or socioeconomic status.
  8. Psn-Pdf (pdf file)

    psnet.ahrq.gov/node/42824/psn-pdf
    February 27, 2014 - Quality of reporting of studies evaluating time to diagnosis: a systematic review in paediatrics. … Quality of reporting of studies evaluating time to diagnosis: a systematic review in paediatrics. … https://psnet.ahrq.gov/issue/quality-reporting-studies-evaluating-time-diagnosis-systematic-review- … paediatrics Despite a rapidly growing number of studies evaluating time to diagnosis in pediatrics, … https://psnet.ahrq.gov/issue/quality-reporting-studies-evaluating-time-diagnosis-systematic-review-paediatrics
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_surveillance.pdf
    September 01, 2012 - There were too few studies of color Doppler to perform full meta-regressions. … Two studies reported the accuracy of MRI by patient age. 30,44 One of these two studies (Bluemke … Because there were only three studies, we could not fit the data in a bivariate model. … There were too few studies of color Doppler to perform full meta-regressions. … Because there were only three studies, we could not fit the data in a bivariate model.
  10. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
    September 01, 2011 - cohort studies of adults (≥18 years) with chronic GERD. … For studies with surgical procedures, we accepted only RCTs or cohort studies examining total (Nissen … For studies with endoscopic procedures, we included only RCTs or cohort studies examining products approved … Two sham-controlled studies and six cohort studies evaluated the effectiveness of EndoCinch. … EndoCinch™ Low • Two sham-controlled studies and 6 noncomparative cohort studies evaluated the effectiveness
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
    October 01, 2013 - between 1996 and 2010, from 52 studies per 1000 patients to 149 studies per 1000 patients.2 The reported … Most of the primary studies focus on specific subsets of patients that had imaging studies or procedures … We will compare the included observational studies to any RCTs. … the main analysis to these studies. … would be conducted by excluding these studies.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
    April 02, 2013 - of findings from these studies as well. … studies. … The authors might consider including those studies that lost participants in follow up if the studiesStudies that used the universal prevention approach and studies that used the targeted prevention … inclusion as those studies could be more accurately characterized as studies of treatment of PTSD
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
    January 01, 2010 - While Canonica et al refer to placebo-controlled studies, our review included studies comparing SIT … Our review included European SLIT studies and also U.S. studies (4 studies). Table E1-Appendix E. … First, the number of U.S. studies is less than 7% of the total number of studies so is a very small … Our review included all studies that met our inclusion criteria: we included studies from Europe, Asia … From the 142 studies included, only 16 studies (11%) came from the U.S.; 12 studies in the SCIT group
  14. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
    September 01, 2011 - prospective cohort studies). … We rated the quality of individual studies as good, fair, or poor; only good or fair studies are included … Of these studies, there were 17 head-to-head RCTs (19 articles): 7 studies (9 articles) were head-to-head … rate 0 NA No eligible studies identified.c ECT vs. sham Remission rate 0 NA No eligible studies identified.c … No studies of psychotherapy were identified.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
    April 01, 2010 - • Observational studies. … Assessment of Methodological Quality of Individual Studies We will evaluate the quality of studies … , cross-sectional studies, or case series). … For diagnostic studies, we will apply the Quality Assessment of Diagnostic Accuracy Studies (QUADAS … Assessment of Methodological Quality of Individual Studies We will evaluate the quality of studies according
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
    September 18, 2012 - What AEs are collected in clinical studies (phases I–IV) and in observational studies containing a … What AEs are collected in clinical studies (phases I–IV) and in observational studies containing a … Criteria for Inclusion/Exclusion of Studies in the Review The following publication types / studies … in the United States • Non–English-language studiesStudies not reporting or mentioning AEs. … The following types of studies will be included: • Studies that compare AEs between a vaccinated
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
    November 01, 2013 - EPCs can consider studies to be consistent when the CIs of individual studies overlap a summary effect … reporting bias for such studies. … in question; these studies are of unequal size; smaller and larger studies do not differ substantially … the smaller studies. … in evidence base Consider the number of studies and total sample size across studies assessed at risk
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_disposition-comments.pdf
    August 06, 2014 - We restricted to studies in children ages 0-12 and studies published from 2000 to the present. … , large multi-site observational studies)? … were follow-ups to studies evaluated in the 2011 review. … report followup data from studies in the prior review. … comorbid conditions, not all studies in the review.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
    November 24, 2014 - While retrospective studies were included in this comparative effectiveness review, only studies with … Again, given that there were so few studies, more detail about the studies, the baseline characteristics … This level of granularity was not given in the studies included, as none of the included studies related … Studies addressing once daily dosing of aminoglycosides were not included because studies were required … Six studies (4 clinical trials and two cohort studies met inclusion criteria, but only one study, with
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
    November 01, 2013 - , with observational studies representing 17 percent of all studies registered in ClinicalTrials.gov … studies,37-39 although some have suggested that requirements to register observational studies might … and unpublished studies submitted by manufacturers to identify any remaining unpublished studies or … , studies of complementary and alternative interventions, and non-English language studies. … • Arranges outcomes in columns and studies in rows for all included studies.