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  1. www.uspreventiveservicestaskforce.org/uspstf/recommendation/ovarian-cancer-screening-1996
    January 01, 1996 - In screening studies, including a recent study of more than 22,000 women, the reported sensitivity was … Studies of stored sera have found that about one half of women who developed ovarian cancer had elevated … Prospective studies involving asymptomatic women are needed, however, to provide definitive data on the … Studies have shown that routine ultrasound testing of asymptomatic women has a low yield in detecting … Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/pth_4-Mnau_pZubaefDvUk
    January 01, 2020 - When to Start Screening Clinical trials, observational studies, and modeling studies all demonstrate … Many other risk factors have been associated with breast cancer in epidemiologic studies, but most of … , ecologic and cohort studies, and decision modeling. … These studies assess the effects of the preventive service on health outcomes. … This conclusion is therefore unlikely to be strongly affected by the results of future studies.
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/r9MoffF79edExY5m2V_koD
    May 01, 2021 - No studies addressed screening for iron deficiency or iron deficiency anemia during pregnancy. … For iron deficiency anemia, studies from the prior USPSTF review were included. … Studies of nonpregnant indi- Figure 1. … observational studies on harms. … of treatment No studies NA NA NA NA Insufficient NA KQ4: Harms of treatment No studies NA NA NA NA
  4. www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - However, there is limited evidence from external validation and implementation studies to demonstrate … Only 3 trials included majority populations of Black individuals (range, 50% to 72%). 1 Studies most … There was also a reduction in perinatal mortality (pooled RR, 0.79 [95% CI, 0.66-0.96]; 11 studies; … Maternal complications of preeclampsia (eg, eclampsia or death) rarely occurred in studies and could … Studies are needed that provide more information on the following.
  5. JAMA (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/pACFPdCoN8fVoddBs-_CLE
    November 12, 2019 - These studies assess the effects of the preventive service on health outcomes. … ), anxi- ety (13 studies), and depression (7 studies). … ,91-97 oophorectomy (7 studies),98-104 or salpingo- oophorectomy (2 studies)91,105 were associated with … Nine studies evaluated breast cancer worry or distress after genetic test- ing. … , and 2 studies reported decreased worry.112,113 Studies reporting anxiety related to genetic testing
  6. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary8/abdominal-aortic-aneurysm-screening-2014
    January 15, 2014 - for AAA screening benefits as well as RCTs and cohort and registry studies for harms in adults with … Although we decided a priori to pool studies for all outcomes using DerSimonian–Laird random-effects … on the effectiveness of rescreening, 7 studies addressing the harms of 1-time and repeated screening … Deaths and their causes were ascertained from death certificates in all studies, and 3 used a blinded … All studies were conducted in mostly white populations.
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/36geybKjEXsHDoPkRR5KVZ
    June 01, 2008 - ; studies of glycemic control, with CHD outcomes, in screening- detected populations; studies of optimal … Other studies have exam- ined whether these tests predict future CVD events. … No studies reported adverse effects of receiving a diagnosis of IFG or IGT, and no studies examined … data from 20 studies of 95, 783 individuals followed for 12.4 years. … These studies assess the effects of the preventive service on health outcomes.
  8. www.uspreventiveservicestaskforce.org/uspstf/recommendation/chlamydia-and-gonorrhea-screening-september-2014
    September 22, 2014 - Screening Intervals In the absence of studies on screening intervals, a reasonable approach would be … Research Needs and Gaps Studies evaluating the effectiveness of different screening strategies for … Currently, no studies provide data about the potential adverse effects of screening in any population … Sensitivity of NAATs for gonorrhea ranged from 90% to 100% in studies without major limitations. … No subsequent studies met inclusion criteria for the current USPSTF review 7 , 11 .
  9. www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-counseling
    March 20, 2018 - Most studies of interventions to increase sun protection behaviors have been limited to persons with … Three studies provided the intervention in conjunction with well-child visits. … , and 2 studies used “appearance-focused” messages. … Ideally, research studies would provide measurements of sun exposure, sunburn, precursor skin lesions … Such studies would also assess whether these behaviors continue after trial completion.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
    November 24, 2020 - Studies rated as poor were excluded. 14 Poor-quality studies typically had several major risks of bias … Few studies were powered for mortality, and neither individual large studies nor the pooled estimate … Summary of Study Characteristics of All Included Studies (94 Studies, N = 52,174), Overall and by Risk … , No. (%) All studies Hypertension a Dyslipidemia b Mixed risk factors All studiesstudies BMI, –0.5 (95% CI, –0.7 to –0.2); 30 studies Evidence primarily in medium- and high-contact
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/2VxcSta8ko2L_GC97XjZqm
    September 01, 2015 - The Task Force reviewed research studies on the potential benefits and harms of screening all pregnant … It also looked at studies on the benefits and harms of all pregnant women taking an iron supplement … They found no studies that looked at the harms of routine IDA screening. … Available studies on routine iron supplementation showed that it likely has few or mild harms. … An evidence document provides more detail about the studies the Task Force reviewed.
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RwHjq3L5fN5gdWsp_sSwA3
    August 02, 2018 - More studies of adolescents in primary care settings are needed. … Twenty-eight studies were fair quality and 17 were good quality. … Most studies took place in the United States (62%), and 51% of the studies recruited patients from primary … In many studies, sensitivity improved at lower cutoffs. … In most studies, the range of sensitivity was 0.73 to 0.97 for fe- males (95% CI, 0.62-0.99; 5 studies
  13. Cancer Older Adults (pdf file)

    www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/cancer_older_adults.pdf
    September 28, 2012 - Studies comparing trajectories of quality-adjusted survival with and without screening to assess net … quality and quantity of evidence, older adults need to be enrolled in screening trials and clinical studies … First, many screening studies do not even consider harms of screening, so we do not know their extent … Future research should look at large longitudinal population studies such as registries, cohort studies … , or studies based on longitudinal medical records to better understand these issues.
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
    August 23, 2022 - Results: Twenty-six studies were included: 22 trials (N = 90,624) with 6 months to 6 years of follow-up … Searches were supplemented by reference list review of relevant articles; studies from the prior USPSTF … The population was adults 40 years or older without prior CVD events; studies of populations in which … For harms, large cohort (n >10,000) and case-control (>500 cases) studies of statin use vs nonuse were … , consistency of results between studies, and directness of evidence.
  15. www.uspreventiveservicestaskforce.org/uspstf/recommendation/chlamydia-and-gonorrhea-screening
    September 14, 2021 - Seven new fair-quality studies with more than 93,000 participants were included in the analysis. 34-39 … In asymptomatic individuals, 3 studies with 71,636 participants that used a risk score to identify … Nine fair-quality studies in more than 16,000 participants indicated that screening for chlamydia and … Studies evaluating the effectiveness of screening asymptomatic men to reduce infection complications … Studies with direct evidence on the effectiveness of screening pregnant persons, testing extragenital
  16. www.uspreventiveservicestaskforce.org/uspstf/recommendation/genital-herpes-serologic-screening
    February 14, 2023 - have examined the screening accuracy of serologic tests for HSV-2 in pregnant persons. 1 , 6 Studies … Harms of Screening and Treatment The USPSTF found no new studies reporting on the harms of screening … Studies assessing screening test accuracy and predictive value in primary care settings in the US that … Studies that enroll enough participants from populations disproportionately affected by HSV (based on … High-quality studies that provide consistent evidence about the effectiveness of behavioral counseling
  17. www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening
    February 02, 2021 - Of the 4 included studies, none used angiography as a reference standard and only 2 enrolled patients … Pooled data from 7 cohort studies found that 3.3% (95% CI, 2.7%-3.9%) of patients died or had a stroke … The studies included in the review included participants with these risk factors, and the USPSTF found … Comments pointed to several studies that demonstrate the benefits of CEA over best medical therapy to … The USPSTF added language about the new studies it considered.
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/e6_WqcwDGhgT6bQfmk3Hqj
    February 02, 2021 - Of the 4 included studies, none used angi- ography as a reference standard and only 2 enrolled patients … Pooled data from 7 cohort studies found that 3.3% (95% CI, 2.7%-3.9%) of patients died or had a stroke … The studies included in the review included participants with these risk factors, and the USPSTF found … Com- ments pointed to several studies that demonstrate the benefits of CEA over best medical therapy … The USPSTF added language about the new studies it consid- ered.
  19. untitled (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/QWUmLEKdwcYA-AKGp5dNaQ
    August 09, 2016 - These studies assess the effects of the preventive service on health outcomes. … This conclusion is therefore unlikely to be strongly affected by the results of future studies. … . inconsistency of findings across individual studies. limited generalizability of findings to routine … Both studies took place in school settings. … No studies screened for multifactorial dyslipidemia by measuring levels of non–HDL-C.
  20. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/depression-in-adults-screening
    January 26, 2016 - Pregnant and Postpartum Women Twenty-three studies (n = 5398), including 8 studies of the English-language … Most studies were published in the 1990s and early 2000s; only 1 (in older adults) of the 9 trials was … The other 8 non-CBT studies examined a diverse range of interventions but did not provide sufficient … No additional studies addressing harms of screening were identified in the review. … The 2009 USPSTF review found 7 studies that compared suicide-related events in adults who received SSRIs

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