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January 01, 2001 - KQ1 Direct Grade
assignment/
health
equity
RCTs, controlled
trials, and
observational
studies … Studies
should be well
designed§ with low
risk for bias using
robust
contemporaneous
comparison … groups
Children and
adolescents
aged 5 to 17
years; studies
should be
representative
of the … Studies
should be well
designed§ with low
risk for bias using
robust
contemporaneous
comparison … KQ1 Direct Grade
assignment/
health
equity
RCTs, controlled
trials, and
observational
studies
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/nfP93-Hva3bvxkvkBStTgm
Harms: Randomized,
controlled trials; cohort
studies; case-control
studies; diagnostic
accuracy … studies; large
case series; and
systematic reviews and
meta-analyses (of
included study designs) … ,
comparative
effectiveness studies of
various screening
timepoints, modeling
studies
multiple … ; case-control
studies; diagnostic
accuracy studies; large
case series; comparative
effectiveness … studies;
modeling studies; and
systematic reviews and
meta-analyses (of
included study designs)
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary3/chlamydia-and-gonorrhea-screening-september-2014
September 23, 2014 - Inclusion criteria were less restrictive for effectiveness studies than diagnostic accuracy studies because … in 3 studies 24 , 26 , 27 . … Studies were lacking for most key questions, and the number, quality, and applicability of studies varied … ; previous reviews cited descriptive studies predating the searches
No studies
NA
NA
NA
NA … No studies met inclusion criteria.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan54/colorectal-cancer-screening-june-2016
April 17, 2014 - (e.g., small studies aimed at evaluating new endoscopy technologies, studies with operator or resource … ; or case-control studies
KQ 2: Systematic reviews (of included study designs), trials, cohort or … well-conducted nested case-control diagnostic accuracy studies, screening registry studies
KQ 3: … ; cohort studies; systematically selected case series
Poor-quality studies with a fatal flaw … Diagnostic accuracy studies without colonoscopy as a reference standard, diagnostic accuracy studies
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-in-pregnancy-screening-september-2018
August 31, 2017 - or adult women, at any time during pregnancy, who are not known to have syphilis infection
KQ 3: Studies … in women living with HIV
KQ 3: Studies of penicillin treatment in nonpregnant women or men; studies … on psychosocial harms; studies on screening test inaccuracy must define their criteria for false-positive … Programme)
Study design
KQ 1: Randomized, controlled trials; before-after and ecologic studies … ; case-control studies; diagnostic accuracy studies; large case series; systematic reviews and meta-analyses
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www.uspreventiveservicestaskforce.org/uspstf/document/reducing-risk-for-mother-to-infant-transmission-of-hepatitis-c-virus-a-systematic-review-for-the-us-preventive-services-task-force/hepatitis-c-screening-2013
November 15, 2012 - Fourteen studies (2 good-quality, 4 fair-quality, and 8 poor-quality studies) found no clear association … Fourteen studies (2 good-quality, 2 fair-quality, and 10 poor-quality studies) found no association between … We selected for full review randomized trials, cohort studies, and case–control studies that evaluated … Labor Management
Internal Fetal Monitoring
Three studies (2 good-quality 5 , 16 studies and … shortcomings in the studies.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/asymptomatic-bacteriuria-in-adults-screening
December 28, 2017 - with a comparator of no screening or no treatment
KQs 2, 4: RCTs, observational cohort studies … with and without a comparison group, registry studies
KQs 1, 3:
Nonpregnant adults: Study designs … other than RCTs
Pregnant women * : Study designs other than RCTs or observational cohort studies … with a comparator of no screening or no treatment
KQs 2, 4: Case control studies, case series and … case reports, qualitative studies
Countries
Nonpregnant adults: Studies conducted in countries
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evidence gaps
listed below, the USPSTF provides guidance to researchers and funders on the types of studies … ;
nonrandomized
studies of
interventions with
contemporaneous
control groups
KQ4: Studies from … KQ5: Association
studies of
intermediate
outcomes/health
outcomes link
(observational
studies … ; other
controlled
observational
studies
KQ2: Studies from
KQ1 and large
uncontrolled
observational … studies
KQ3: Association
studies of
intermediate
outcomes/health
outcomes link
(observational
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan142/obstructive-sleep-apnea-in-adults-screening-january-2017
October 30, 2014 - of adults with acute stroke or other acute conditions that can trigger onset of OSA
Studies … of persons with suspected but unconfirmed OSA
Setting
Studies conducted in countries … )
KQs 4, 5, 8: For nonsurgical treatments, interventions studied only in laboratories (e.g., studies … and cross-sectional studies that developed or evaluated screening questionnaires or clinical prediction … included in KQs 4 or 5 reporting both change in AHI and change in a health outcome
KQ 7: Studies
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/drug-use-illicit-screening
October 20, 2016 - interventions for nondependent drug use, with or without addressing other substances or behaviors
Studies … (tobacco or alcohol), severity of the disorder, and presence of comorbid mental health conditions
Studies … , case control studies, time series studies, before-after studies with no comparison group, cross-sectional … studies, case studies, case series, editorials/commentaries
Country
Studies conducted in countries … whose primary results were published from 1992 to present
Studies whose primary results were published
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www.uspreventiveservicestaskforce.org/uspstf/document/ResearchPlanFinal/carotid-artery-stenosis-screening-december-2007
January 23, 2014 - Setting
Studies conducted in developed countries.
… KQ 3: Studies on accuracy of screening must include a comparison with angiography; studies on reliability … No comparison; nonconcordant historical controls; comparative studies of CEA versus CAAS. … KQ 7: Systematic reviews or multi-institution, prospective studies (RCTs or cohort studies) that report … KQ 8: Systematic reviews or multi-institution, prospective studies (RCTs or cohort studies) that report
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan36/carotid-artery-stenosis-screening-december-2007
January 23, 2014 - Setting
Studies conducted in developed countries.
… KQ 3: Studies on accuracy of screening must include a comparison with angiography; studies on reliability … No comparison; nonconcordant historical controls; comparative studies of CEA versus CAAS. … KQ 7: Systematic reviews or multi-institution, prospective studies (RCTs or cohort studies) that report … KQ 8: Systematic reviews or multi-institution, prospective studies (RCTs or cohort studies) that report
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/khUSqr94jqWPErt9ZRnQ95
October 01, 2009 - trial), case–cohort studies, and
nested case–control studies. … We included studies in which some patients had
cardiovascular disease at baseline only if the studies … In general, we selected cohort studies over
nested case–control studies, good-quality studies over fair … -
quality studies, studies that adjusted for more Framingham
risk variables, studies with longer follow-up … within studies is
low.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary4/colorectal-cancer-screening-2008
October 15, 2008 - Poor-quality studies were excluded. … Studies ( n = 86 498) provided estimates for Magstream (3 studies; n = 37 330 ), OC-Hemodia (3 studies … (Key question 3a)
Colonoscopy
3 retrospective cohort studies, 14 prospective cohort studies … Flexible sigmoidoscopy
2 retrospective cohort studies, 6 prospective cohort studies
5 studies were … , cohort studies; cross-sectional studies; systematically selected case series
Any
Adverse events
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www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-pregnant-women-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
November 15, 2012 - No studies
No studies
Not applicable
No studies
No studies
No studies
No study compared clinical … No studies
No studies
Not applicable
No studies
No studies
No studies
No study evaluated … Not applicable
No studies
No studies
No studies
No new studies evaluated effects of prenatal … Reference 40 was a randomized trial; all other studies were cohort studies. … , 3 studies on mitochrondrial effects, 4 studies on congenital abnormalities, 2 studies on infant neurodevelopment
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary14/bladder-cancer-in-adults-screening
October 15, 2010 - We focused on studies done in primary care settings but also included studies conducted in occupational … (KQ 2)
0 studies
All studies enrolled patients with previous bladder cancer or signs and symptoms … (KQ 3)
0 studies
No studies met inclusion criteria
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-
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No evidence. … (KQ 4)
0 studies
No studies met inclusion criteria
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-
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No RCTs or controlled observational … studies were identified.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/T6auAz-64DpreTqycmvSJr
January 01, 2001 - • These studies should focus on enrolling
children from groups with the greatest
burden of speech … These types of studies would
help to understand if changes in speech
and language outcomes translate … Studies
should be well
designed§ with
low risk for bias
using
contemporaneous
comparison … Standardization of outcome measurement across
studies would greatly strengthen the evidence
base and … trials
KQ3: Asymptomatic
children age 5 years or
younger.** Studies
should be representative
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
September 06, 2016 - 0.90 (57 studies; n = 4378). … For harms of treatment (KQ5), prospective cohort studies and case-control studies were also eligible. … No eligible studies were identified. … , 45 , 58 , 76 less than 5% in 9 studies, 64 , 65 , 77 , 78 , 80 , 82-85 and not reported in 5 studies … TB IGRA test used in US studies higher than threshold used in non-US studies.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/g-b8KbTXYe2vnW2zJKGoPU
April 01, 2015 - No randomized
controlled screening studies are available. … due to the limited number
of studies for each Key Question and
differences among studies in design, … found both
clinical and methodologic
heterogeneity and did not combine
the studies. … Although an older meta-
analysis of 28 studies (randomized
controlled trials and cohort studies)
found … Limitations of our report include
restricting inclusion of studies
published in English and studies
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/L5UwXoftg4JHw4buVDhjUT
October 01, 2010 - We focused on studies done in primary care
settings but also included studies conducted in occupa-
Figure … (KQ 2)
0 studies All studies enrolled patients
with previous bladder
cancer or signs and
symptoms of … (KQ 3)
0 studies No studies met inclusion
criteria
– – –
Findings: No evidence. … (KQ 4)
0 studies No studies met inclusion
criteria
– – –
Findings: No RCTs or controlled observational … studies were identified.