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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/yj6JY8HJZtbnv5qDPxS3PX
    evidence gaps listed below, the USPSTF provides guidance to researchers and funders on the types of studies … Gap‡ Study Characteristics Population Intervention/ Comparison Outcomes/ Timing Setting Studies … KQ2 Indirect Grade assignment Randomized trials, Cross- sectional and cohort studies of diagnostic … KQ2 Direct and indirect Grade assignment Randomized and non-randomized studies Adults (age … KQ 1,3,4,5 Direct and indirect Grade assignment Randomized and non-randomized studies Adults
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/BhnZRA--TRpXdg9_tYmZ_M
    April 05, 2016 - STUDY SELECTION Two reviewers independently screened abstracts and studies. … , and cohort studies were considered. … studies. … ; however, other studies in- cluded patient-reported increase in symptoms. … Conducted in Australia, Sweden for pre-BD studies; Greece for post-BD.
  3. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/child-maltreatment-counseling-2004
    March 09, 2004 - There are no studies about harms of screening and interventions. … We excluded studies about patients presenting with trauma. … Six studies met eligibility criteria. … Studies need to consider the influence of observer or surveillance bias. 26 , 41 , 55 In studies of … Case Control Studies Criteria Accurate ascertainment of cases?
  4. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary22/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation-september-2015
    March 30, 2015 - Although many older observational studies, including uncontrolled and cross-sectional studies, have shown … When good- and fair-quality studies were available, poor-quality studies were excluded. … Due to methodological shortcomings in the studies and differences across studies in design, interventions … or inability to pool studies. … ‡ Some studies are included for >1 KQ.
  5. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary10/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
    March 15, 2009 - Only 2 of the 5 studies included women. … We limited our search to English-language studies, human studies, and studies of nonpregnant adults and … We excluded studies of poor quality. … We ultimately included 4 studies, which we discuss. … criteria, or standard appraisal of studies.
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/t6yV6ZMHngeWgmTsoMMefM
    March 01, 2009 - Only 2 of the 5 studies included women. … We limited our search to English-language studies, human studies, and studies of nonpregnant adults and … We excluded studies of poor quality. … We ultimately included 4 studies, which we dis- cuss. … criteria, or standard appraisal of studies.
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/LSbrGFWSvekVzhcxwjTuXv
    February 01, 2016 - Studies most clinically relevant to practice in the United States were selected over studies that were … designed as RCTs, cohort studies, case–control studies, and systematic reviews; criteria to rate other … Observational Studies Three good-quality systematic reviews of observa- tional studies of screening … Observational Studies Five case-series studies compared breast cancer diagnoses in populations of women … based on 7 case– control studies.
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/genital-herpes-screening-november-2016
    August 06, 2015 - Analytic Framework *Studies … † Eligible studies with mixed populations (e.g., studies that enroll a subset of participants who … ‡ Studies that test for both HSV-1 and HSV-2 (simultaneously) will not be excluded if they meet the … are no exclusion criteria for the date of publication for eligible studies for KQs 2 and 3. … If a recent good-quality systematic review is identified, relevant primary studies published since the
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Yc24U4wMLXGoqE5NjwRVA6
    April 17, 2018 - Random-effects meta-analysis used when at least 3 similar studies were available. … lists of pertinent articles, and studies suggested by reviewers, were reviewed. … Characteristics of included studies are reported in Table 1. … in only 2 studies. … and osteoporotic fractures in most studies.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan104/skin-cancer-screening-july-2016
    July 17, 2014 - Evidence-based Practice Center will use to search for publications and to determine whether identified studies … of doctor-patient relationship quality Study design Fair- to good-quality studies … , including cohort and case-control studies; ecologic studies KQs 2, 6: Same as above, as well … as case series on the harms of screening Poor-quality studies with a fatal flaw; studies outside … The USPSTF also refined the search window to include studies published between January 1, 1995 and March
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-pregnant-women/human-immunodeficiency-virus-hiv-infection-screening
    June 15, 2017 - similar to that in the United States, except for randomized trials of antiretroviral therapy Studies … of screening conducted in low and middle-income countries, unless fair- or good-quality studies in the … or were previously taking antiretroviral therapy prior to pregnancy; women with acute HIV infection; studies … outcomes Study designs KQs 1–4: Randomized, controlled trials and controlled observational studies … KQ 5: Randomized trials and controlled observational studies KQs 1–4: Modeling studies
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/7eLc5kBtomL_HKpYDwsFPf
    July 01, 2009 - In addition, studies not published in English and studies of community- or home-based screening were … ( n = 2) Catarac t RCT s ( n = 2) SR (of observational studies ) ( n = 1) Observational studies … We excluded studies of strictly community- or home-based vision screening but in- cluded mixed studies … 8 studies of diagnostic accuracy Fair Methodological shortcoming in trials; no studies assessed accuracy … of LASIK; keratitis rates range from 0% to 3.4% in 6 studies of LASIK and 4 studies of LASEK AMD �
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/abTWXPvJyAMcqN9KcEt-vt
    September 06, 2016 - 0.90 (57 studies; n = 4378). … For harms of treatment (KQ5), prospective co- hort studies and case-control studies were also eligible … .73-75 In 3 studies, fewer than 25% of the participants were BCG vaccinated.28,30,72 Thirteen studies … 0 Studies included for KQ1 0 Studies included for KQ43 Studies included for KQ3 5 Studies included … less than 5% in 9 studies,64,65,77,78,80,82-85 and not reported in 5 studies.73,79,86-88 Pooled estimates
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/YSj5xRQc9DroH8gpUYsoFA
    December 01, 2007 - In general, studies were selected if they were large, multi- institution, prospective studies that reported … Thirteen observational studies were sec- ondary analyses of administrative databases: 2 studies used … The studies included patients who did and did not have neurologic symptoms, but we reviewed only studies … Six of the studies collected informa- tion on race; in those studies, most participants were white (range … The systematic review of 103 studies found an overall stroke and death rate at 30 days of 3.0% in studies
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/8dzfZ_s3tZueoEh5Xzh-3A
    July 26, 2016 - studies were included for all key questions. … For studies focusing on morbidity and mortality, studies of skin cancer mortality, all-cause mortality … For studies on early detection of skin cancer, studies that evaluated either American Joint Committee … ; poor-quality studies were ex- cluded. … Consistency among studies was high.
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/827CwGYMVawpVoVg_syJpF
    October 01, 2015 - Several studies reported inconsistent findings on these health outcomes. … Change in Iron Status No studies were found that directly assessed the association between change in … Studies used varying doses of iron, ranging from 20 to 200 mg per day. … These studies assess the effects of the preventive service on health outcomes. … This conclusion is therefore unlikely to be strongly affected by the results of future studies.
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/6-CojmU4NZFXUKggs-_YFU
    January 01, 2010 - There was no significant difference in the results when poor studies were excluded. … Breastfeeding intervention studies often combined interventions. … Main Effects (Meta-regression) Combined Effects Education Studies Education Support Studies Plus Support … ,61 their impact in studies of clinic-based behavioral counseling is uncertain. … , all studies were pooled to display mean differences and confidence boundaries.
  18. peds20151711 1..8 (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/72ybMHDdg9WyFzrYMBF4ch
    August 01, 2015 - However, the USPSTF found no studies on these harms. … Studies on the potential harms of screening and interventions are also needed. … The review excluded studies that focused on acquired, focal causes of speech and language delay. … The majority of studies included 2- and 3-year-olds, but the ages varied. … ; however, individual studies used different reference standards.
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-YHCmR_8bdShSaMTx6Mrgx
    ambulatory adults age 65 years or older N/A Falls Settings applicable to U.S. primary care Studies … nursing or care homes, or other long-term care facilities) KQ 2: Harms outcomes as reported in studiesStudies are needed on the effectiveness and harms of interventions in different functional and risk … More studies are needed on the benefits and harms of educational and psychological interventions … Outcomes/ Timing Setting education via written materials, video, or lecture) or usual care Studies
  20. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary45/skin-cancer-counseling-2012
    May 15, 2012 - For key questions 4 and 5, we included trials, cohort studies, and population-based case-control studies … The ORs and risk ratios, however, should not be compared between studies because the studies used very … These studies showed mixed results: two studies found a statistically significant association between … Four of 5 studies used only a crude dichotomous measure of indoor tanning, and none of these studies … comparisons across studies.

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