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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication
August 01, 2023 - Two investigators independently reviewed English-language randomized studies and nonrandomized cohort … Ineligible studies included poor-quality studies and those focusing solely on persons taking antiseizure … . 5-8 No studies examined differences by race or ethnicity. … Controlled studies of multivitamin supplementation on pregnancy outcomes. … ) or exposure recall bias (in retrospective studies)
3 Studies (2 cohort [3 publications] 5-7 , 1
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
February 09, 2023 - Include
Exclude
Populations
Studies enrolling adolescents * and adults presenting for primary … of diagnostic accuracy are also eligible
KQs 3, 5: Cohort studies with a concurrent control group … reviews ‡
Quality
Studies rated good or fair quality
Studies rated poor quality
Settings … of diagnostic accuracy are also eligible
KQs 3, 5: Cohort studies with a concurrent control group … reviews ‡
Quality
Studies rated good or fair quality
Studies rated poor quality
Setting
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kGvn_HBPEEdfu2rs38VN8_
March 11, 2025 - for food insecurity; instrument accuracy studies of brief
screening tools. … Studies included in these reports were
evaluated for inclusion in the current review. … Studies were restricted to English-language studies con-
ducted in the US, with no age restriction on … was
required, but no minimum follow-up was required for studies
reporting harms (KQ3, KQ5). … 0 Studies NA NA NA Insufficient NA
KQ4: Benefits of interventions
29 Studies (n = 74 292):
1 Randomized
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-older-adults
June 12, 2025 - all Key Questions, we will describe the population and intervention characteristics of the included studies … KQ 2 : Diagnostic accuracy studies
KQ 3: Randomized, controlled trials; nonrandomized controlled … studies
KQ 4: Randomized, controlled trials
KQ 5: Randomized, controlled trials included in KQ4 … ; large observational studies for pharmacotherapies
KQs 1, 4: Observational studies
KQ 2: Case-control … Study quality
Studies at low or moderate risk of bias
Studies at high risk of bias (according
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/GcjfCZtGpACQMv2KScLbEu
June 11, 2019 - RESULTS Sixty-two studies were included in this review, including 29 new studies. … Randomized
clinical trials (RCTs), cohort studies, and case-control studies of
pregnant adolescents ( … Twenty-nine
new studies in 36 articles were included (2 trials in 2 articles9,10
and 27 cohort studies … in 34 articles11-44), and 33 studies in
35 articles (7 trials in 9 articles,45-53 25 cohort studies … and 4 cohort studies that found
increased preterm birth associated with ART and 1 RCT and 3
cohort studies
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chlamydia-and-gonorrhea-screening
September 14, 2021 - Results: Twenty-seven studies were included (N = 179,515). … controlled observational studies. … were asymptomatic in 3 studies, 20-22 symptom status was not reported in 3 studies, 24 , 26 , 27 and … Important gaps include lack of studies on psychosocial or other harms related to screening, studies comparing … Update: 7 cross-sectional studies (n = 93,137)
Not addressed in prior review Seven studies evaluated
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/screening-anxiety-children-adolescents
March 29, 2022 - in which more than 50% of the population are age 19 years or older
Studies limited to populations … of diagnostic test accuracy **
KQ 3: RCTs, CCTs, observational studies
KQ 4: RCTs
KQ 5: … after identified systematic reviews that include observational studies
All other study designs … ; case-control studies (i.e., studies that limit the study sample to only those with and without known … As a result, we are not restricting treatment studies to screen-detected populations alone.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/screening-depression-suicide-risk-children-adolescents
August 13, 2020 - in which more than 50% of the population are age 19 years or older
Studies limited to populations … of diagnostic test accuracy **
KQ 3: RCTs, CCTs, observational studies
KQ 4: RCTs
KQ 5: … RCTs
Systematic reviews of comparative cohort and case-control observational studies
Harms of … instruments; case-control studies (i.e., studies that limit the study sample to only those with and … As a result, we are not restricting treatment studies to screen-detected populations alone.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
August 20, 2024 - For iron deficiency anemia, studies from the prior USPSTF review were included. … observational studies on harms. … As in the prior USPSTF review, no studies evaluated the benefits or harms of screening. … per key question (KQ) exceeds the total number of studies because some studies were applicable to multiple … Fair
Low
Studies conducted in US (2), Norway, Australia, rural China (3), Denmark
Largest studies
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obstructive-sleep-apnea-in-adults-screening
March 04, 2021 - by age, sex, BMI category, and OSA severity*
All KQs: Children and adolescents; pregnant women; studies … of adults with acute stroke or other acute conditions that can trigger onset of OSA; studies focused … , diagnosis, or treatment of OSA among persons with a rare condition (e.g., acromegaly)
KQs 4–6: Studies … of persons with suspected but unconfirmed OSA
Setting
Studies conducted in countries categorized … , or combined screening approaches KQ 3: Studies eligible for KQ 1 or 2 that report harms of screening
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
July 07, 2022 - ; and other controlled observational studies
KQ 2: Studies from KQ 1 and large uncontrolled observational … studies
KQ 1: Uncontrolled studies
Abbreviations: KQ = key question, NICU = neonatal intensive … ; and other controlled observational studies
KQs 2, 4: Studies included from other KQs and large uncontrolled … observational studies
KQ 5: Association studies
Uncontrolled studies (KQs 1 and 3)
Abbreviations … Current criteria specifies inclusion of U.S. primary care–relevant studies, including studies from relevant
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
February 22, 2024 - plan to describe the participant characteristics and major intervention components of the included studies … are not available in those settings
KQs 1–5: Studies conducted in non-very high Human Development … Index countries, unless fair- or good-quality studies from the United States are not available … observational studies, modeling studies
Timing
KQ 5: Long-term followup, defined as ≥2 years … KQ 3: RCTs and large (n>250) observational studies that controlled for potential confounders
KQs
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
November 30, 2023 - are not available in those settings
KQs 1–5: Studies conducted in non-very high Human Development … Index countries, unless fair- or good-quality studies from the United States are not available … observational studies, modeling studies
Timing
KQ 5: Long-term followup, defined as ≥2 years … KQ 3: RCTs and large (n>250) observational studies that controlled for potential confounders
KQs … 1–3: Modeling studies
Timing
KQ 3: Any timing
Abbreviations: 3TC = lamivudine;
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
November 18, 2021 - What is the evidence from modeling studies about the effectiveness of risk screening strategies that … that exclusively enroll adults younger than age 40 years
KQs 1–3: Studies that exclusively enroll … Studies of FRAs or ORAs using split sample validation. … Cohort studies and systematic reviews of cohort studies are also eligible for KQ 3 only. … Studies that include gender-diverse individuals, including those who have undergone gender-affirming
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4TToeya43r5Qc5A6TjFGWS
August 01, 2023 - Two investigators independently reviewed English-language
randomized studies and nonrandomized cohort … Ineligible studies included poor-quality studies and
those focusing solely on persons taking antiseizure … .5-8 No studies examined differences by race or ethnicity. … ) or exposure recall bias
(in retrospective studies)
3 Studies (2 cohort [3 publications5-7], 1 case-control8 … Controlled studies of multivitamin
supplementation on pregnancy outcomes.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/latent-tuberculosis-infection-screening
June 17, 2021 - Studies that combine children and adults or studies with both HIV-negative and HIV-positive persons ( … KQ 2: RCTs, cohort studies, and cross-sectional studies. … (including network meta-analyses), RCTs, prospective cohort studies, and case-control studies. … KQ 4: Studies eligible for KQ 1 or 2. … KQ 2: For specificity outcome: Studies in high-TB–burden countries. †
Quality
Studies rated
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
April 20, 2023 - Intimate Partner Violence
Include
Exclude
Populations
Studies enrolling adolescents … of diagnostic accuracy are also eligible
KQs 3, 5: Cohort studies with a concurrent control group … reviews ‡
Quality
Studies rated good or fair quality
Studies rated poor quality
Settings … of diagnostic accuracy are also eligible
KQs 3, 5: Cohort studies with a concurrent control group … reviews ‡
Quality
Studies rated good or fair quality
Studies rated poor quality
Setting
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening
April 20, 2023 - Intimate Partner Violence
Include
Exclude
Populations
Studies enrolling adolescents … of diagnostic accuracy are also eligible
KQs 3, 5: Cohort studies with a concurrent control group … reviews ‡
Quality
Studies rated good or fair quality
Studies rated poor quality
Settings … of diagnostic accuracy are also eligible
KQs 3, 5: Cohort studies with a concurrent control group … reviews ‡
Quality
Studies rated good or fair quality
Studies rated poor quality
Setting
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/wKfFrTpC8VtforKLrqGpjQ
April 18, 2023 - Poor-quality studies were excluded. … (29 articles) were included, comprising 3 studies
from the previous review16 and 17 new studies, after … Three studies
(10 articles)17-26 were included for KQ1; 6 studies (7 articles)27-33
for KQ2; 2 studies … Characteristics of Included Studies
Characteristic
No. of studies
No. of people
analyzedc
Reporting … All
studies included for KQ4 focused on
melanoma; no included studies
contributed data for keratinocyte
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/perinatal-depression-interventions-to-prevent
February 23, 2023 - plan to describe the population, risk assessment, and intervention characteristics of the included studies … Studies restricted to screening for and treatment of depression during pregnancy or in the postpartum … partners
Studies limited to individuals in institutions (e.g., psychiatric inpatients, prison inmates … , juvenile detention centers, foster homes, or group homes)
Studies limited to persons in long-term … care or residential facilities
Studies in mixed populations that include >50% of any of the above