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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
    December 19, 2013 - We will include randomized controlled trials (RCTs), cohort studies, and case-control studies for all … Studies will be rated as “good,” “fair,” or “poor,” or as specified by the particular criteria. … We will not exclude studies rated as being poor in quality a priori, but poor- quality studies will be … if discrepancies between studies are present. … as well as new studies identified in current searches.
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    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
    December 01, 2009 - studies. … All of the studies were diagnostic cohort studies that enrolled a population of women found to have suspicious … Freehand automated gun: 5 studies of 610 biopsies. US vacuum-assisted: 7 studies of 507 biopsies. … US automated gun: 16 studies of 7,124 biopsies. … Freehand automated gun: 5 studies of 610 biopsies. US vacuum-assisted: 7 studies of 507 biopsies.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
    January 10, 2012 - of studies will be based on the KQs and are described in the previous PICOTS section. … trials and controlled or comparative observational studies • KQ 4: randomized trials, cohort studies … Non–English-Language Studies Non–English-language studies will be included in the searches and translated … Individual studies will be rated as “good,” “fair,” or “poor.” … studies are present.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
    March 16, 2017 - in these studies; 4) assess the strength of evidence for studies of differential comparative effectiveness … What are the characteristics of the participants in these studies? KQ 3. … What are the characteristics of the participants in these studies? … Any comparative studies (KQ 4) or long-term followup studies (KQ 7) found from existing systematic reviews … studies and descriptions of statistical significance of studies, emphasizing larger studies with better
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - We also hand-searched reference lists of relevant studies, searched for unpublished or ongoing studies … Risk of Bias Assessment of Individual Studies We assessed risk of bias of included studies using … For uncontrolled longitudinal studies, we used the same criteria as for cohort studies, but did not … Rather, we synthesized studies qualitatively. … In addition to studies of naloxone administration by EMS personnel, studies of naloxone administration
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
    April 01, 2013 - We include studies of both universal and targeted prevention. … We rated the studies as low, medium, or high risk of bias. … If medium or low risk-of-bias studies were available, we omitted from our main analyses studies deemed … risk of bias studies. … these high-risk-of-bias studies in our analyses.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
    April 01, 2013 - We searched for ongoing studies of currently approved treatments or studies of unapproved treatments … We did not look for studies that would fall outside the scope of the treatment CER, such as studies … We focused on identifying ongoing studies (rather than completed studies or terminated studies) conducted … Lack of studies in screen detected patients. No studies identified. Not applicable. … Cohort Studies Advantages of cohort studies for producing a valid result.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
    January 01, 2011 - Observational Studies in Other Situations It can be challenging to search for observational studies … MEDLINE EMBASE Cohort studies/ comparative study/ follow-up studies/ prospective studies/ risk … MEDLINE EMBASE CINAHL 1 Epidemiologic studies/ 2 Exp case control studies/ 3 Exp cohort studies/ … )).mp. 11 (Case control adj (study or studies)).tw. 12 (follow up adj (study or studies)).tw. … control studies/ 3 Correlational studies/ 4 Nonconcurrent prospective studies/ 5 Cross sectional studies
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
    August 12, 2016 - We have clarified which studies evaluated ethyl esters. … Some of the exclusions of studies on the basis of sample size seem arbitrary: for example, studies of … As the reviewer notes, we excluded weight loss studies. … Weight loss intervention studies were excluded. … because of incomplete reporting by several studies.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
    January 01, 2014 - Criteria for Inclusion/Exclusion of Studies in the Review - Included studies will be limited to those … Finally, we will ask the TEP to assess our included studies and to provide references for any studiesStudies will be weighted by sample size. … studies that include long-term, clinical outcomes and in applying standards of precision to these studiesstudies.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nitric-oxide_research-protocol.pdf
    September 06, 2016 - ) • In vitro, and in vivo studies • Non-original data (e.g. … • Qualitative studies • Animal studies Publications Any language Non-English abstract Abbreviations … We will evaluate heterogeneity between studies using I2 indicator. … In diagnostic studies, observational studies can start as high strength of evidence for diagnostic accuracy … vs. estimates derived from studies at low risk of bias; or 2) when all the available studies (in a
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
    December 20, 2011 -  Studies published in English. …  Studies from 1995-current. …  Studies that do not have a direct comparison between NH and HCBS (e.g., studies that compare one … We will abstract data on characteristics of population served from cross-sectional studies and studies … and studies that report casemix.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
    August 22, 2008 - Criteria for Inclusion/Exclusion of Studies in the Review Studies will be included in the evaluation … Studies will be included in the key question 5 evaluation if they are 1) studies of rhGH therapy, 2) … Epidemiologic studies/ 2. Exp case control studies/ 3. Exp Cohort Studies/ 4. … (follow up adj (study or studies)).tw. 8. … Epidemiologic studies/ 2. Exp case control studies/ 3. Exp Cohort Studies/ 4.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_surveillance.pdf
    January 08, 2013 - No studies reported the prevalence of joint swelling in children. No new studies identified. … No new studies identified. NA All three experts felt the conclusion was up to date. … None of the studies specifically addressed children with joint swelling. … No new studies identified. NA All three experts felt the conclusion was up to date. … None of the studies specifically addressed children with joint swelling.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_disposition-comments.pdf
    October 05, 2010 - Introduction DASH measure is commonly used in studies The DASH is listed in the summary of frequently … There are two studies (#168, and #145) comparing nonoperative treatments. … An update of the review may be merited once these studies have been completed and published. … (e.g., retrospective cohort studies were included). … We hope this explanation is helpful in clarifying our rationale for excluding these studies.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
    September 01, 2008 - These are only two studies. How large were the studies? … were there any studies by the IHS? … Such studies can be analyses of administrative data, observational studies, or other designs depending … Noninferiority vs. superiority studies: Studies designed to demonstrate non-inferiority or equivalence … However, most studies have not been designed to test this, and these studies had very low statistical
  17. effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
    January 01, 2018 - Harms (KQ2) were reported in 126 studies (93%). … Of the 135 studies, 89 (66%) were RCTs, 6 (4%) were NRCTs, and 40 (30%) were observational studies. … A total of 20 studies compared different doses of the same antipsychotic, and 56 studies compared one … Overall, the observational studies were of quite high quality; of 40 studies, 4 (10%) were rated as … Most studies had treatment durations between 4 and 12 weeks; nine studies were 6 months or longer.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
    December 11, 2018 - We will exclude cohort studies, case-control studies, case reports, and case series. … studies are present. … from poorer-quality studies. … Random effects across studies are assumed and if estimates across studies vary widely, profile likelihood … and studies rated as poor.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
    August 07, 2012 - Criteria for Inclusion/Exclusion of Studies in the Review - Studies will be included or excluded in … Prospective and retrospective cohort studies and case-control studies will be included for KQs that … the report to include more studies from English-speaking countries. … Assessment of Methodological Quality of Individual Studies - To assess the risk of bias of studies, … London: Chapter 8: Assessing risk of bias in included studies.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
    November 01, 2012 - studies, and before-and-after studies that compared the outcome of patients taking one of the therapies … Quality Assessment of Individual Studies We assessed the quality of included studies by using recommendations … Studies that met five or more criteria were classified as effectiveness studies. … The followup in these studies ranged from 12 to 26 weeks. … Adverse events were not evaluated in these studies.

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