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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
    May 19, 2011 - Randomized controlled trials, nonrandomized comparative studies, and cohort studies; for adverse events … included in relevant review articles and any additional eligible primary studies. … Assessment of Methodological Quality of Individual Studies For those KQs with applicable studies … We will describe our logic where studies are not unanimous. … B can only be assessed by evaluating studies of A vs. placebo and B vs. placebo).
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
    July 01, 2017 - The full report, listing all studies, is available at www.effectivehealthcare.ahrq.gov/renal-cancer. … were open-biopsy studies. … b Fifteen of the studies concerned open biopsy, and one concerned fine needle aspiration. … SEER studies: HR 1.18 (0.94 to 1.42) Non-SEER studies: HR 1.08 (0.87 to 1.33) ��� Metastasis-free survival … SEER studies: HR 1.23 (1.13 to 1.33) Non-SEER studies: HR 1.09 (0.88 to 1.34) ��� Radical Nephrectomy
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
    September 01, 2011 - No other studies met the criteria. … No studies were overlooked, to my knowledge. … All studies of safety were addressed in KQ3. … Studies like this are not science. … many of the studies, but is appropriate.
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
    September 01, 2011 - Summary characteristics of the included studies Number of Characteristic Studies References Study Design … No studies reported neonatal hypocalcemia or ileus. … Despite this thorough process, the number of identified studies was very small—we had too few studies … Observational studies. … Since observational studies are susceptible to the effects of confounding, future observational studies
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/worker-safety-wellness-protocol.pdf
    October 26, 2024 - trials, nonrandomized comparative studies (nonrandomized controlled trials, observational studies … We will exclude cohort studies that do not have a comparison group, as well as all cross-sectional studies … cohort studies with a comparison group • Pre-post studies (with adjustment for confounders) … and articles that are not primary studies. … (i.e., studies such as cohort studies and before-after studies) in which it can be demonstrated that
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
    September 01, 2012 - Included studies reflected 63 distinct study populations: 28 RCTs, 4 clinical trials, 14 cohort studies … , 8 case series, 6 case-control studies, and 3 cross- sectional studies. … Two studies of gel (total n=556) did not. … in the two studies that used vaginal gel. … Five studies, all conducted before 1980, used other progestogens.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
    December 19, 2013 - We will include randomized controlled trials (RCTs), cohort studies, and case-control studies for all … Studies will be rated as “good,” “fair,” or “poor,” or as specified by the particular criteria. … We will not exclude studies rated as being poor in quality a priori, but poor- quality studies will be … if discrepancies between studies are present. … as well as new studies identified in current searches.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-applicability_methods.pdf
    July 01, 2012 - Which studies should be included and which excluded? … Prevalence of condition in practice and in studies. … “alloy” standard in studies. Alternate or “usual” test used in the studies. … D-dimer studies in which it is unclear when results were available relative to DVT imaging studies … Thus excluding studies with older technologies and presenting results of included studies by slice thickness
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
    January 10, 2012 - of studies will be based on the KQs and are described in the previous PICOTS section. … trials and controlled or comparative observational studies • KQ 4: randomized trials, cohort studies … Non–English-Language Studies Non–English-language studies will be included in the searches and translated … Individual studies will be rated as “good,” “fair,” or “poor.” … studies are present.
  10. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
    December 01, 2009 - studies. … All of the studies were diagnostic cohort studies that enrolled a population of women found to have suspicious … Freehand automated gun: 5 studies of 610 biopsies. US vacuum-assisted: 7 studies of 507 biopsies. … US automated gun: 16 studies of 7,124 biopsies. … Freehand automated gun: 5 studies of 610 biopsies. US vacuum-assisted: 7 studies of 507 biopsies.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
    March 16, 2017 - in these studies; 4) assess the strength of evidence for studies of differential comparative effectiveness … What are the characteristics of the participants in these studies? KQ 3. … What are the characteristics of the participants in these studies? … Any comparative studies (KQ 4) or long-term followup studies (KQ 7) found from existing systematic reviews … studies and descriptions of statistical significance of studies, emphasizing larger studies with better
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - We also hand-searched reference lists of relevant studies, searched for unpublished or ongoing studies … Risk of Bias Assessment of Individual Studies We assessed risk of bias of included studies using … For uncontrolled longitudinal studies, we used the same criteria as for cohort studies, but did not … Rather, we synthesized studies qualitatively. … In addition to studies of naloxone administration by EMS personnel, studies of naloxone administration
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
    April 01, 2013 - We include studies of both universal and targeted prevention. … We rated the studies as low, medium, or high risk of bias. … If medium or low risk-of-bias studies were available, we omitted from our main analyses studies deemed … risk of bias studies. … these high-risk-of-bias studies in our analyses.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-executive-summary.pdf
    January 01, 2025 - We selected studies that were study author-identified interventions (regardless of whether any component … not-TIC, including a comparator of any kind allowed us to focus attention on comparative studies that … Only four of the included studies were cluster RCTs, the remaining studies were variations of NRSIs. … All included studies were assessed as high risk of bias. … Studies did not report harms, adverse events, or unintended consequences of TIC.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-white-paper.pdf
    December 01, 2024 - We did not assess the quality of individual studies or the strength of evidence across studies. … Excluded Studies Appendix C. … studies. 8 3. … labels with either the final included studies in the report (18 studies) or human- generated labels … (3 studies).
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
    February 05, 2025 - We will limit the literature search to studies published after the year 2000 as older studies may not … studies) • In vitro studies • Nonoriginal studies (e.g. … published in English • Studies published after the year 2000 • Non-English language studies • … We will evaluate heterogeneity between studies using I2 indicator. … versus estimates derived from studies at low risk of bias or (2) when the majority of available studies
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-research-executive-summ.pdf
    March 01, 2025 - Collectively, this review represents over 750 studies. … the number of new studies we included. … The full list of included studies can be found in our full report. Figure A. … Lighter blue shading indicates evidence from newer primary studies. … We also searched for newer studies to include the latest evidence for each outcome.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
    March 14, 2024 - We will limit the literature search to studies published after the year 2000 as older studies may not … studies) • In vitro studies • Nonoriginal studies (e.g. … published in English • Studies published after the year 2000 • Non-English language studies • … We will evaluate heterogeneity between studies using I2 indicator. … versus estimates derived from studies at low risk of bias or (2) when the majority of available studies
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
    January 01, 2024 - Most of the included studies enrolled patients on VKAs; 2 studies included patients on DOACs. … Jang 202122 included 12 studies (5 RCTs, 4 controlled cohort studies, 3 single- group pre-post studiesstudies) or no bleeding events in either group (two studies). … The review included 17 studies, conducted in New Zealand (9 studies), Canada (4 studies), the United … (two studies) or no bleeding events in either group (two studies)
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-269-respectful-maternity-care-summary.pdf
    January 01, 2024 - • Based on analyses of psychometric properties presented in 24 validation studies, 10 tools were … Twenty-four validation studies (3 observational studies, 21 cross- sectional studies) evaluated 12 tools … for measuring RMC, including studies validating tools in other languages. … For KQ3 and 4, there were no studies of RMC effectiveness on infant health outcomes and no studies evaluating … Although not formally included as evidence, 77 cross-sectional studies applying the 12 frameworks in

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