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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
    October 05, 2012 - Data from all 5 studies was pooled. … For example, for ICU LOS, (actually only four studies provided evidence and table 7 says 5 studies) … , two studies reported significant difference and two studies reported non- significant difference – … The 2 excluded studies reported effects larger than any of the included studies, so if these 2 studies … samples of the 2 smaller studies.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_executive.pdf
    August 01, 2012 - ; prospective and retrospective cohort studies; interrupted time series studies with comparison groups … ; and stepped-wedge design studies. … ; controlled before-after studies; prospective and retrospective cohort studies; interrupted time series … .10,11,22-25 The remaining studies were cohort studies, including one prospective cohort study,26 one … Duration of studies was generally 1 year.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
    August 31, 2017 - The vast majority of studies combine diagnoses. … The starting point in studies of intervention is high for RCTs and low for observational studies. … SOE is never determined for individual studies. … Studies were clearly described. … as long term studies or studies of moderators or mechanistic studies.
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - We did not a priori exclude studies rated poor quality, but poor quality studies were considered to be … between studies were present. … in 7 studies. … ) Insufficient for sex and race (most studies included a majority of women, but studies didn’t evaluate … A simple and valid tool distinguished efficacy from effectiveness studies.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
    September 01, 2017 - We identified 16 new studies. … , and case-control studies … No studies were identified. … 11 studies). … ), number of drinking days (2 studies), and drinks per drinking day (2 studies).
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - that have only few studies. … only few studies. … When interpreting the results, the precision of the studies is as relevant as the number of studies. … number of studies … While it is not recommended to combine studies using RD when baseline risks are different among studies
  7. effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
    February 24, 2016 - uncontrolled single-arm studies or studies without adequate descriptions of tumor localization. … as well as studies of therapy. … Studies are clearly described. … Despite some merit to large, retrospective single-institution studies, the majority of those studies … are single-arm modality studies and not comparative (i.e. lower level of evidence) studies.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
    May 08, 2013 - Regarding the quality of the studies, we agree that there were many studies of poor quality and/or small … Hence, earlier studies will not fair as well as more recent studies provided invesitgators of more … studies. … reported for some studies but unavailable for other studies. … studies resemble pilot studies-further complicating the task.
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-2010_research-protocol.pdf
    January 01, 2010 - ); insurance type/status (9 studies); nutritional status (2 studies); provider and institutional policy … , and maternal age (>15 studies); sleep and fatigue (2 studies); maternal weight, obesity, body mass … index, and height (35 studies); and miscellaneous topics, including studies examining large cohorts … of women with multiple contributing risk factors (>50 studies). … For observational studies (specifically the pre- and post- studies of health systems changes), we will
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
    November 01, 2009 - Out of 243 papers, 185 were single-arm retrospective studies, and another 35 studies were prospective … Seven studies (3 percent) focused on a pediatric population; most of the remaining studies reported … Most studies reported patient relevant-clinical outcomes: 151 studies (62 percent) described overall … photon radiation for other cancers (six studies); surgery (three studies). … The remaining 220 studies were single-arm studies (case series or cohort studies); 185/220 were retrospective
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_executive.pdf
    November 01, 2012 - These were simple before-after studies or controlled before- after studies (2 of 88) with two group … rates for multiple individual infections.14,35,61 These studies are treated as separate studies, one … Most studies used multiple QI strategies; only 12 studies used a single QI strategy. … Fourteen of the studies adjusted for potential confounders, and the results of these studies appeared … Most studies of QI strategies are effectiveness studies rather than efficacy studies.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
    September 18, 2012 - What AEs are collected in clinical studies (phases I–IV) and in observational studies containing a … What AEs are collected in clinical studies (phases I–IV) and in observational studies containing a … Criteria for Inclusion/Exclusion of Studies in the Review The following publication types / studies … in the United States • Non–English-language studiesStudies not reporting or mentioning AEs. … The following types of studies will be included: • Studies that compare AEs between a vaccinated
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
    April 01, 2010 - • Observational studies. … Assessment of Methodological Quality of Individual Studies We will evaluate the quality of studies … , cross-sectional studies, or case series). … For diagnostic studies, we will apply the Quality Assessment of Diagnostic Accuracy Studies (QUADAS … Assessment of Methodological Quality of Individual Studies We will evaluate the quality of studies according
  14. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
    September 01, 2011 - prospective cohort studies). … We rated the quality of individual studies as good, fair, or poor; only good or fair studies are included … Of these studies, there were 17 head-to-head RCTs (19 articles): 7 studies (9 articles) were head-to-head … rate 0 NA No eligible studies identified.c ECT vs. sham Remission rate 0 NA No eligible studies identified.c … No studies of psychotherapy were identified.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
    January 01, 2010 - While Canonica et al refer to placebo-controlled studies, our review included studies comparing SIT … Our review included European SLIT studies and also U.S. studies (4 studies). Table E1-Appendix E. … First, the number of U.S. studies is less than 7% of the total number of studies so is a very small … Our review included all studies that met our inclusion criteria: we included studies from Europe, Asia … From the 142 studies included, only 16 studies (11%) came from the U.S.; 12 studies in the SCIT group
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
    April 02, 2013 - of findings from these studies as well. … studies. … The authors might consider including those studies that lost participants in follow up if the studiesStudies that used the universal prevention approach and studies that used the targeted prevention … inclusion as those studies could be more accurately characterized as studies of treatment of PTSD
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
    October 01, 2013 - between 1996 and 2010, from 52 studies per 1000 patients to 149 studies per 1000 patients.2 The reported … Most of the primary studies focus on specific subsets of patients that had imaging studies or procedures … We will compare the included observational studies to any RCTs. … the main analysis to these studies. … would be conducted by excluding these studies.
  18. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
    September 01, 2011 - cohort studies of adults (≥18 years) with chronic GERD. … For studies with surgical procedures, we accepted only RCTs or cohort studies examining total (Nissen … For studies with endoscopic procedures, we included only RCTs or cohort studies examining products approved … Two sham-controlled studies and six cohort studies evaluated the effectiveness of EndoCinch. … EndoCinch™ Low • Two sham-controlled studies and 6 noncomparative cohort studies evaluated the effectiveness
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_surveillance.pdf
    September 01, 2012 - There were too few studies of color Doppler to perform full meta-regressions. … Two studies reported the accuracy of MRI by patient age. 30,44 One of these two studies (Bluemke … Because there were only three studies, we could not fit the data in a bivariate model. … There were too few studies of color Doppler to perform full meta-regressions. … Because there were only three studies, we could not fit the data in a bivariate model.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
    July 01, 2014 - Studies that had serious flaws were rated high risk of bias, studies that met all criteria were low … In this report, direct evidence included studies (trials or observational studies) that compared pregnant … Indirect evidence included studies (trials or observational studies) of pregnant or postpartum women … The majority of the evidence was from observational studies (124 unique studies); we included only … Few studies reported race or socioeconomic status.

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