-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
February 01, 2015 - Recommendation: We recommend that newly identified studies be clearly distinguished from
studies in … If the new studies would change the conclusions or the SOE judgments or the
new studies are in some … We recommend that newly identified studies be clearly distinguished from studies in the existing review … When is it okay not to add new studies (or conduct a search for new studies)? … Grading practices range from grading all studies using own criteria to grading the new studies and comparing
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
June 01, 2021 - (97 studies
reported in 190 publications). … Eligible studies included RCTs as well as large non-randomized controlled trials and
cohort studies … Studies had to report on effects of radiation therapy in the 1990s or later and we
included studies … studies
varied. … Despite the large number of identified research studies, analyses were
limited as studies evaluated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - studies, and seven pre/post studies) met inclusion criteria for the
effectiveness of pharmacologic treatments … Twenty-four studies (2 RCTs of diet, 6 pre/post studies of diet, and 16 pre/post
studies of surgery) … For ketogenic diet
(KD), all 7 studies (2 RCTs and 5 pre/post studies) support the conclusion that KD … Twelve studies of pharmacologic interventions, four studies of dietary treatments, and
12 studies of … Only
pharmacotherapy studies collected and reported harms systematically.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-executive-summary.pdf
November 01, 2024 - Improving this evidence base will require more robust long-term
studies. … Results
Of 11,015 identified studies, 82 articles detailing 81 distinct studies met our inclusion … Among these, 13 studies rated as low to moderate risk of bias were synthesized. … , such as prospective cohort studies. … across studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-222-evidence-summary-health-equity.pdf
January 01, 2020 - Studies of the effectiveness of clinician-patient
interventions (KQ3) were differentiated from
studies … One hundred twenty-
five articles representing 120 unique studies met
inclusion criteria; eight studies … a50 studies in 54 publications, b26 studies in 27 publications, c13 studies in 14 publications, d1 study … Studies involved screening for colorectal,
breast, or cervical cancer, including five studies
that … Few studies addressed the
effects of impediments and barriers to preventive
care, including no studies
-
effectivehealthcare.ahrq.gov/products/single-group-studies/white-paper
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effectivehealthcare.ahrq.gov/products/methods-guidance-observational-studies/slides
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-executive-summary.pdf
May 01, 2025 - No studies were identified for some questions and
outcomes. … We included randomized controlled trials,
nonrandomized intervention studies, and observational studies … Studies
were individually evaluated for risk of bias. … Relaxing sample size criteria did not result in the inclusion of
additional studies, as most studies … Studies reported sample sizes from 56 to 1,455.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - Choice of Statistical Model for Combining Studies
Quantitative Synthesis
Chapter 3. … Choice of Statistical Model for Combining Studies
Prepared for:
The Agency for Healthcare Research and … .
− Therefore differences between studies’ treatment effects are due to random variability … • When a systematic review includes small and large studies, and
results of small studies are different … ► For studies with zero events in one arm, or studies with sparse binary data
but no zero events,
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
November 01, 2024 - List of Studies in the Systematic Reviews and Primary Studies
Appendix F. … • Clinical practice guidelines
• Laboratory studies
• Animal studies
• Non-clinical studies
Language … • Decrease in 9/11
studies
• Decrease in 4/5
studies
• Decrease in 1/3
studies
NR (no Meta … • Decrease in 9/11 studies
• Decrease in 4/5 studies
• Decrease in 1/3 studies
Not reported … List of Studies in the Systematic Reviews and Primary Studies
Appendix F.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-261-postpartum-care-executive-summary.pdf
June 01, 2023 - Eighty-three
studies were conducted in the United States and 9 in Canada. … The 92 studies included 50
RCTs (N = 477,954 participants) and 42 NRCSs (i.e., observational studies … For contraceptive care (1 study) and
for breastfeeding care (2 studies), the studies did not address … The included studies were mostly at moderate or high risk of bias. … General PP
care (2
studies): No
conclusion
?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
January 01, 2012 - of net benefit given the costs of studies. … , and similarity of included studies. … Included studies of sufficient validity and quality
4. … Insufficient data: too few primary studies, or studies that are too small (sample size inadequate or … The use of
systematic reviews when designing studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nursing-staff-shortages.pdf
October 01, 2024 - selection criteria, or standard appraisal of studies. … Description of Included Studies
To efficiently describe eligible primary studies, a single team member … analysis of the findings of those studies. … Criteria for Assessing Internal
Validity of Individual Studies. U.S. … ROBINS-I: a tool for assessing risk of bias in non-
randomised studies of interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
January 01, 2024 - o Overall, most studies were conducted in the United States (58%) and had
sample sizes in the range … data on race only; data were not provided for
race or ethnicity in 42 percent of studies. … o Almost a third of studies (30%) targeted specific types of trauma: combat-
related trauma was the … and 403 nonpharmacologic studies (trials with no
medication arms). … The newly added studies had sample sizes ranging from 22 to 1,001,
with most studies (61%) having a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
January 01, 2021 - (used for
identifying additional studies)
• In vitro studies, nonoriginal data
(e.g., narrative … Publications • Studies published in English only
• Studies published in peer-
reviewed journals … • Studies published at and after the
year 2000
• Non-English language studies
Abbreviations: BMI … For
nonrandomized studies, including quasi-experimental studies, controlled before-and-after
studies … studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
January 01, 2023 - o 20 percent of studies targeted a specific trauma type, and about half of
studies allowed a mix of … of the 388 studies
using RoB 2 and a second reviewer checked for accuracy. … and 360 nonpharmacologic studies (trials with no
medication arms). … The
newly added studies had sample sizes ranging from 20 to 916, with most studies having a
sample … This update also includes RoB assessment for all 436
previously included studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-executive-summary.pdf
November 01, 2024 - When more than two
studies were available, different designs and/or methods to calculate the estimate … requirements were used, making comparisons between studies difficult … Future
studies, using this new method, should focus on population groups including
infants, children … Results
We identified 11,408 studies, of which 68 articles reporting on 66 unique studies
were eligible … We found very few studies for protein or
indispensable amino acids across all populations.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation-surveillance-160902.pdf
October 08, 2025 - )"all"studies"
were"not"included"or"excluded"from"the"original"systematic"review,"b)"all"studies"were"not … /$(7120)$
2$$$$$exp$case$control$studies/$(779866)$
3$$$$$exp$cohort$studies/$(1534155)$
4$$$$$Case … 4776)$
7$$$$$(Follow$up$adj$(study$or$studies)).tw.$(41015)$
8$$$$$(observational$adj$(study$or$studies … $We$aimed$to$include$all$studies$of$multidisciplinary$interventions. … $Limiting$included$
studies$to$those$published$in$English$is$not$idealk$however,$studies$conducted$
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-disposition-comments_0.pdf
March 03, 2025 - In this
review, we included both exposure
and intervention studies. … Defining low-carb in the
scientific literature: A scoping review of clinical studies. … We did not restrict our
studies based on carbohydrate
intake levels. … We did not restrict our studies based
on carbohydrate intake levels. … As responded above, we
did not exclude studies with low
carbohydrate intakes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
November 18, 2024 - • Studies that exclusively enroll participants
hospitalized with an illness or injury
• Studies … studies
• Case-control studies
• All other study designs
Geographic
Location
• Locations … The one exception is studies of
adolescents; for those meeting all other eligibility criteria, studies … If older,
seminal studies or
studies cited in the
prior guideline are
needed for context
we will … If
older, seminal
studies or studies
cited in the prior
guideline are
needed for context
we will