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  1. effectivehealthcare.ahrq.gov/products/osteoporosis-bone-fracture/research
  2. effectivehealthcare.ahrq.gov/products/ptsd-adults-trauma-interventions/research-protocol
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
    January 01, 2024 - 160ml per day Asked to refrain from consuming soft drinks and provided background material on previous studies … radiologically New symptomatic or radiographic stone or growth (>50%) of an existing stone Imaging studies … deviation SE standard error SES socioeconomic status STROBE Strengthening the Reporting of Observational Studies
  4. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - This expert also noted that larger and long-term studies are needed to evaluate the safety and efficacy … another expert representing a research perspective opined, “With the marginal success rate from early studies … providing long-term safety data with new drug applications and committing to long-term postmarket studies … experts expressed concern regarding gastrointestinal side effects and listed a need for long-term studies
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-drugs-utilization_research.pdf
    March 01, 2011 - Utilization of antidiabetic drugs among Medicare beneficiaries with diabetes, 2006-2009 Diabetes Treatment Data Points #9 Biguanides (i.e., metformin) were the most commonly used antidiabetic drug class among Medicare beneficiaries from 2006 to 2009, followed by sulfonylureas, insulins, and thiazolidinediones…
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
    June 01, 2010 - patients have affective disorders, and an additional 10% have eating disorders. 17,18 There are few studies
  7. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - This expert also noted that larger and long- term studies are needed to evaluate the safety and efficacy … and a time table for assessments.”37 FDA has required the manufacturer to conduct 10 postmarketing studies … experts expressed concern regarding gastrointestinal side effects and listed a need for long-term studies … With the approval, FDA required that the manufacturer conduct six postmarketing studies, including … For instance, one expert representing a clinical perspective commented, “Published studies have shown
  8. effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
    December 22, 2014 - the manufacturer is not pursuing marketing approval for a dual regimen containing asunaprevir, studies … chronic HCV genotype 1 infection.6 Although the functions of NS5A are not fully defined, in vitro studies … genotype 2 (n=26) and genotype 3 (n=42) achieved SVR12 rates of 88% and 67%, respectively.23 In studies … infections without IFN or RBV, some experts thought.82,83,85,87 Data have been reported from multiple studies … Multiple, ongoing studies with large patient populations were also encouraging, the experts noted.
  9. effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_june_2012.pdf
    January 01, 2012 - 2012 and 2013. 11,12 According to a recent manufacturer press release, a pooled analysis from 4 studies … Preclinical studies demonstrated that florbetapir was highly specific in binding to beta-amyloid aggregates
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-draft-report-rob.xlsx
    January 01, 2017 - RCT RefID Author, year (Trial/Study Name if applicable) Is randomization adequate? Yes/No/Unclear/NR Is allocation concealment adequate? Yes/No/Unclear/NR Are groups similar at baseline? Yes/No/Unclear/NR Is the outcome assessor (interviewer) masked? Yes/No/Unclear/NR Is the data analyst masked? Yes/No/…
  11. effectivehealthcare.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
    July 09, 2013 - Preclinical studies demonstrated that florbetapir was highly specific in binding to beta-amyloid aggregates … completed.12,13 According to a company press release issued in April 2012, a pooled analysis from 4 studies
  12. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - Studies have demonstrated that the formulation of exenatide used in ITCA 650 is stable within the Duros … The studies will include a broad range of patients whose diabetes is uncontrolled by oral antidiabetes … In some studies, LAGB has been associated with T2DM resolution (or improvement) in as many as 80% of … BMIs of less than 35 kg/m2 enrolled in 5 randomized controlled trials and 6 observational clinical studies … Also, two pharmacokinetic-pharmacodynamic studies will be initiated to characterize dose response and
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
    January 01, 2015 - information on clinical, safety, cost, and reimbursement for health care interventions) Cochrane (cost studies … Again, formal studies are needed to determine the cost-effectiveness. … Robust studies measuring outcomes such as reduced admissions, reduced returns to the ED, and reduced … Several cost-effectiveness studies indicate that TAVI is likely to be cost-effective for patients ineligible … To date, no U.S. cost-effectiveness studies comparing transcatheter mitral valve repair with medical
  14. effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
    November 01, 2016 - PREGNANCY, INCLUDING PRETERM BIRTH #12 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 12: Pregnancy, Including Preterm Birth Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane …
  15. effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
    November 01, 2016 - PREGNANCY, INCLUDING PRETERM BIRTH #12 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 12: Pregnancy, Including Preterm Birth Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road …
  16. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
    January 01, 2012 - The theory underlying the use of a texting platform is based on studies that have shown that (unidirectional … . since its launch in 2010. 2,3 The theory underlying the use of a texting platform is based on studies
  17. effectivehealthcare.ahrq.gov/products/study-design-framework/research
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
    October 08, 2025 - Details of included studies Author, Year Study Design Country Setting/Transition Adult, Adolescent,
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-app-e.xlsx
    January 01, 2022 - Risk of bias assessment for nonrandomized studies of intervention Author, Year Did the Study Attempt
  20. effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
    January 01, 2017 - Outcomes from comparative cohort studies addressing Key Question 1 Author, Year Country Quality Rating … Outcomes from comparative cohort studies addressing Key Question 2 Author, Year Country Quality Rating … Outcomes from comparative cohort studies addressing Key Question 3 Author, Year Country Quality Rating

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