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1701. For women, when comparing noninvasive testing,which testing method (echocardiography, MIBI-SPECT, pharmacological testing, etc.) is more accurate in diagnosing coronary artery disease. There has been inadequate studies done on women for… | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-women-when-comparing-noninvasive-testingwhich-testing-method-echocardiography-mibi-spect-pharmacological-testing-etc-is-more-accurate-in-diagnosing-coronary-artery-disease-there-has-been-inadequate-studies-done-on-women-

1702. Osteoporosis-Bone-Fracture Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
      March 01, 2012 - do not apply to most studies that assess adherence. … treatment at 1 year, with adherence ranging widely across studies … No studies describe primary nonadherence (i.e. nonfulfillment). … Newcastle- Ottawa Quality Assessment Scale, Cohort Studies. … Quality Assessment Scales for Observational Studies. 2004. 19.

1703. Disposition of Comments for Imaging Tests for the Staging of Colorectal Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
      November 20, 2014 - that directly compared imaging studies. … When studies are big, smaller difference between studies could be detected along with a higher I2 value … studies only evaluating single modalities. … Of note is the fact that the AHRQ report included only studies on PET/CT, thereby excluding older studies … We suggest assessing the following studies for possible inclusion, as these studies were included by

1704. Disposition of Comments Report for Comparative Effectiveness Review 128 Oral Mechanical Bowel Preparation for Colorectal Surgery (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
      April 30, 2014 - , and reviews studies in progress germane to the topic. … of studies. … Please note that we were referring to study arms (not studies). … Regarding the studies by Zmora and Bucher: we decided to include them with studies using enemas for … Do we know why they were excluded (e.g. non-surgical studies)?

1705. Renal Artery Stenosis Management Strategies: An Updated Comparative Effectiveness Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
      August 16, 2016 - and non-randomized comparative studies. … but excluding PTRAS or medical management studies. … The comparative studies section has separate sections for RCTs and nonrandomized studies. … It was agreed upon to restrict the review of PTRAS cohort studies to prospective studies. … studies.

1706. hemorrhage-postpartum-protocol-140611 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
      June 11, 2014 - We will include population-based case series or registry studies (e.g., studies reporting data from … We will include pre-post studies and other comparative studies of any size and addressing systems-level … prospective/ retrospective cohort studies, case series with ≥50 cases • KQ 5: Pre- and post-studies … Assessment of Methodological Risk of Bias of Individual Studies We will assess the quality of studies … studies with lower risk of bias, i.e., studies of good or fair quality as determined in our quality

1707. The Evidence-Based Care Challenge: A Case Study (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-case-130621.pdf
      June 01, 2013 - The Evidence-Based Care Challenge: A Case Study The Evidence-Based Care Challenge: A Case Study Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD 20850 www.ahrq.gov Contract No. 290-2010-00005C Prepared …

1708. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
      September 08, 2011 - Most studies supporting the use of procalcitonin have utilized the quantitative test which is neither … studies and non-randomized, comparative studies (observational, case-control, and cohort studies) of … relevant to the key questions that were not included in the draft list of selected studies. … Evaluating non-randomised intervention studies. … Such studies would inform one link in an analytic framework, providing indirect evidence.

1709. Diagnosis and Management of Obsessive Compulsive Disorders in Children | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/obsessive-compulsive-disorder/protocol

1710. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1506.pdf
      June 01, 2015 - 5% to 7% of U.S. adults have received a diagnosis of irritable bowel syndrome (IBS); however, some studies … 0.005, in TARGET 1; 41.0% vs. 31.9%, p=0.02, in TARGET 2; 40.2% vs. 30.3%, p<0.001, in the combined studies … Xifaxan has the potential to effectively treat irritable bowel syndrome, according to the clinical studies

1711. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
      February 01, 2015 - Intranasal Insulin for Treatment of Alzheimer’s Disease  Key Facts: Converging neurobiological studies … Larger American- and European-based clinical trials are ongoing; results from these studies may clarify … also exhibit subnormal cerebrospinal fluid insulin levels.3 Additionally, clinical and epidemiologic studies

1712. Horizon-Scan Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
      December 01, 2011 - (Animal and in vitro studies are excluded.) … Is this a human clinical trial (animal and in vitro studies are excluded.) for a novel screening or … Is this a human clinical trial (animal and in vitro studies are excluded.) on a novel surgical approach … News, information on issues & advocacy efforts, case studies on various technologies AdvaMed SmartBrief … Publishes clinical studies translational laboratory findings, mini- reviews and controversial topics

1713. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
      September 26, 2014 - Although many proof-of-concept studies of closed-loop systems (CLSs) have been performed and all the … In June 2014, Russell and colleagues reported outcomes from 5-day, random-order, crossover studies … The studies will include a broad range of patients whose diabetes is uncontrolled by oral antidiabetes … The increase in publication of studies on this population suggests its use is increasing. … Some cited the lack of long-term efficacy studies as potential barriers for clinicians and patients

1714. Cer-235-Pharma-Nonpharm-Ptsd-Update-Appendix-G-1 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
      May 29, 2025 - Study reported on treatment fidelity rating No: • Study did not report on treatment fidelity NA: • For studies

1715. Migraine Protocol-Appendix 20111103 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine_protocol-appendix_20111103.pdf
      November 03, 2011 - limit 19 to (humans) Ongoing registered studies ID Title NCT01035983 Safety and Tolerability

1716. nnovative Methods in Stakeholder Engagement: An Environmental Scan (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2012-1.pdf
      January 01, 2012 - One article examined five case studies of projects to involve stakeholders in Comparative Effectiveness … Hoffman et al. (2010), in a review of case studies related to involving stakeholders in CER, noted … The researchers identified 56 studies and found that researchers most frequently used traditional … How best to engage patients, doctors, and other stakeholders in designing comparative effectiveness studies … Studies in Educational Evaluation, 34, 224–230.

1717. The Refinement of Topics for Systematic Reviews: Lessons and Recommendations From the Effective Health Care Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
      January 01, 2013 - Formulating questions and locating primary studies for inclusion in systematic reviews. … From the literature scan, the studies appear to be heterogeneous with regard to the populations and … We anticipate considerable variation in the basis upon which studies consider care needs to be complex … Despite the diversity of the studies identified in this scan, this would seem to be an encouraging … Nominated KQ Literature scan Many studies use ACR Pediatric 30, a validated composite measure of

1718. Clopidogrel after Drug-Eluting Stent Implantation: Is current practice sufficient (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stent-clopidogrel-practice_research.pdf
      March 01, 2009 - Recent studies of drug-eluting intracoronary stents suggest that current antiplatelet regimens may … Other studies are required to assess relationships between long-term clopidogrel use and the risk for … The central role of the propensity score in observational studies for causal effects.

1719. Machine-Learning-Tools-Appendix-D (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-appendix-d.xlsx
      January 01, 2024 - Artificial Intelligence to Automate Network Meta‑Analyses: Four Case Studies to Evaluate the Potential … Artificial Intelligence to Automate Network Meta‑Analyses: Four Case Studies to Evaluate the Potential … Artificial Intelligence to Automate Network Meta‑Analyses: Four Case Studies to Evaluate the Potential

1720. About the Evidence Synthesis Process | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/about/epc/evidence-synthesis