-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - Ongoing studies and interim analyses.
Sources of Full text publications. … Studies on patients with myelodysplastic
syndrome or acute leukemia. … Inclusion criteria for observational studies are as above except for “Types of
studies.” … New studies will be evaluated against inclusion/exclusion criteria in the same
manner as all other studies … Criteria for Inclusion/Exclusion of Studies in the Review
B.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - We excluded studies of
pediatric MS patients, studies of mitoxantrone (since it has
a maximum lifetime … Risk-of-Bias Assessment of Individual Studies
The risk of bias of eligible studies was assessed by two … Of the remaining 38 articles comprising
27 unique studies, only 16 studies contained complete
information … Harms reported from unique studies included in the analytic set
DMT
Number
of Studies;
Total N; … Studies reporting reasons for discontinuing medication
DMT
Total
Number
of Studies
Adverse
Event
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - These studies vary from small and large nonrandomized, single-center studies to
randomized, prospective … , but also by including
the results of other studies, such as prospective cohort studies and comparative … These studies had the least bias, and the results were
considered valid. … These studies had significant flaws that might have
invalidated the results. … studies with ≥ 100
patients will also be considered.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
January 01, 2013 - in the CER, and some studies had no control or comparison group. … The few new studies we identified supported the conclusions of the original CER. … No new studies identified. NA EPC investigator did not
know. … No observational studies met the
eligibility criteria. … No observational studies met
the eligibility criteria.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
July 21, 2014 - and cohort studies. … For all KQs we will exclude uncontrolled observational studies, case-
control studies, case series, and … case reports, as these studies are less informative than
studies with a control group. … Sources of funding for all studies will also be
recorded. … We will not exclude studies rated as
being high risk of bias a priori, but high risk of bias studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
February 17, 2016 - The 2012 report included studies published from 1980 through May 2011. … There were few studies
evaluating the new factor Xa inhibitors. … We evaluated the number and characteristics of studies—including RCT,
nonrandomized comparative studies … We will explore subgroup
differences within (and possibly across) studies. … "[Mesh] OR (case and control)
OR "Clinical Studies" [Publication Type] OR "Clinical Studies as Topic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-protocol.pdf
April 01, 2014 - Have any of these studies shown improvements in quality of care, improvements in health
outcomes, or … If no such studies of children are available, what studies have assessed whether specific
equivalent … We will also hand search the included
studies of previous relevant reviews and consult with our Key … Comparisons: We plan to include studies that have comparisons of different interventions or
measures … selection criteria, or standard appraisal of studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
October 01, 2007 - studies to be per-
formed after marketing. … Patient safety studies are another example. … Post-marketing studies of drug
efficacy: why? Am J Med. 1985;78:475–480.
4. … Exposure-time-varying hazard function ratios in case-control
studies of drug effects. … Postmarketing studies of drug
efficacy: when must they be randomized?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - these studies. … studies (e.g. … Important
studies
missing? … Important
studies
missing?
KQ2: These studies rely heavily on SSc and liver disease. … Few
studies of IPAH.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - Most studies genotyped and analyzed one of
these variants and not the other while other studies have … ); VerifyNow P2Y12 (28 studies); the
vasodilator-stimulated phosphoprotein (VASP) assay (14
studies … ); Multiplate analyzer (12 studies); and Platelet Function
Analyzer-100 (8 studies). … Unfortunately,
this information is usually based on studies of healthy
volunteers, or studies that … Were
such studies actually identified?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - The characteristics of the studies are
clearly described. … Not aware of any additional studies
that ought to have been included studies that ought to have been … Indeed for some questions, no studies met the criteria. … However, there is a need
for published studies evaluating the effectiveness of risk mitigation studies … Indeed for some questions, no studies met
the criteria.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
August 07, 2018 - and high risk of bias studies. … the lithium studies) were longer. … We have noted when
maintenance studies were
extensions of short-term studies for
acute episodes. … Moreover, 14 studies had
small sample sizes of less than 200 participants and 21 studies (79
percent … I note that the authors explicitly
INCLUDED studies with time to relapse as an outcome, and
studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_disposition-comments.pdf
August 23, 2013 - We note
these studies in the discussion. … Eligibility of studies was not based on the
methodological quality of studies. … Eligibility of studies was not based on the quality
of studies. … studies are flawed. … The studies are not independent as several
studies had multiple treatment arms.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - 3 studies comparing at least 2 different
surgical interventions,54-56 and 11 studies evaluating a
surgical … We included studies without a comparison group because
we anticipated finding few comparative studies … Three studies compared two surgical techniques.54-56 We
also included 11 studies that evaluated a surgical … We expanded our review to include observational studies,
but these studies were largely limited to convenience … Among the studies we identified, we found a
general lack of well-designed, well-controlled studies,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - do not apply to most
studies that assess adherence. … treatment at 1 year, with adherence ranging widely
across studies … No studies describe primary nonadherence
(i.e. nonfulfillment). … Newcastle- Ottawa Quality Assessment Scale, Cohort Studies. … Quality Assessment Scales for Observational Studies. 2004.
19.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
November 20, 2014 - that directly compared imaging
studies. … When studies are big, smaller
difference between studies could be detected along with a higher
I2 value … studies only evaluating single modalities. … Of note is the fact that the AHRQ report included only
studies on PET/CT, thereby excluding older studies … We suggest assessing the
following studies for possible inclusion, as these studies were
included by
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
April 30, 2014 - , and reviews studies in progress germane to the topic. … of studies. … Please note that we were referring to study arms
(not studies). … Regarding the studies by Zmora and Bucher: we
decided to include them with studies using
enemas for … Do we know why they were excluded (e.g. non-surgical
studies)?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
August 16, 2016 - and non-randomized comparative studies. … but excluding PTRAS or
medical management studies. … The comparative studies section has
separate sections for RCTs and
nonrandomized studies. … It was agreed upon to
restrict the review of PTRAS cohort studies
to prospective studies. … studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
June 11, 2014 - We will include population-based case series or registry studies (e.g., studies
reporting data from … We will include pre-post studies and other comparative studies of any size and
addressing systems-level … prospective/ retrospective cohort studies, case series with
≥50 cases
• KQ 5: Pre- and post-studies … Assessment of Methodological Risk of Bias of Individual Studies
We will assess the quality of studies … studies with lower risk of bias, i.e., studies of
good or fair quality as determined in our quality
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Most studies supporting
the use of procalcitonin have utilized the quantitative test which is neither … studies and non-randomized, comparative studies
(observational, case-control, and cohort studies) of … relevant to the key questions
that were not included in the draft list of selected studies. … Evaluating non-randomised intervention
studies. … Such studies would inform one link in an
analytic framework, providing indirect
evidence.