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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
    January 22, 2024 - ● Cohort studies ● Randomized controlled trials (RCTs) ● Non-randomized comparative studiesstudies ● RCTs ● Non-randomized comparative studies o Non-randomized controlled trials o Observational … cohort studies with a comparison group o Pre-post studies Implementation studies without a comparison … We will include filters to remove nonhuman studies and articles that are not primary studies or systematic … be screened for additional eligible studies.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
    December 31, 2022 - For some factors that varied within studies or were specific to certain studies (including demographic … sizes for the available studies were not large. … Future Research and Ongoing Studies Longer followup from the included studies should assess whether … Control for demographic characteristics and other confounders varied across studies, and studies additionally … Ongoing Studies Appendix E.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
    July 19, 2023 - comparing two cohorts, controlled post-only studies, and case-control studies. … We will differentiate short-term and long-term outcomes for all studies. … For the diagnostic studies, we will apply criteria consistent with QUADAS-2. … studies that can strengthen evidence statements through confirmation of results in strong studies. … We will stratify key question 1 (diagnosis) by studies evaluating first-time diagnosis versus studies
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-users-amended-protocol.pdf
    June 21, 2019 - Study design: • Include for all KQs: Clinical trials and observational studies (cohort studies and … case-control studies) … studies … published since 2014 for pearling of studies • Potentially include pre-post studies in the absence … of clinical trials and controlled observational studiesStudies with the following sample sizes
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
    August 24, 2023 - We will not exclude studies based on their duration. … • EXCLUDE: Single group (noncomparative) studies, including case reports or series • EXCLUDE: Studies … for studies in the appendix evidence map. … For studies meeting criteria for full data synthesis (and for other large studies [N≥100 per group … for studies in the appendix evidence map.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
    April 01, 2020 - For the studies that addressed the subgroup KQs (KQs 1b, 2b, 3b, 4b, 5b), we only included studies … We found no studies for KQ 4. … Key characteristics of included studies Study Characteristics Subcharacteristics Number of Studies … 34 56.7 High risk-of-bias studies 25 41.7 Study quality for harms Low risk-of-bias studies 1 1.7 Some … concerns for risk-of-bias studies 23 38.3 High risk-of-bias studies 14 23.3 Unclear risk of bias 1 1.7
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
    January 01, 2024 - of adults o Parallel or cross-over randomized controlled trials (RCTs)  n ≥25/group* • Studies … of children o Parallel or cross-over RCTs  n ≥25/group* o Nonrandomized comparative studies  … Key Questions • Observational studies that do not account for confounders • Analyses of dietary … Data Extraction and Data Management Data from eligible studies will be extracted into SRDR+. … ROBINS-I: a tool for assessing risk of bias in non- randomised studies of interventions.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
    January 01, 2024 - c (n) = number of studies reporting this characteristic at baseline. … ) [SOE] Pain Severity Effect Size (N Studies) [SOE] Function Effect Size (N Studies) [SOE] … ) [SOE] SAE Effect Size (N Studies) [SOE] Dizziness Effect Size (N Studies) [SOE] Nausea … Effect Size (N Studies) [SOE] Sedation Effect Size (N Studies) [SOE] Comparable THC/CBD – … in the United States, studies on long-term outcomes, studies on nonneuropathic chronic pain, studies
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ongoing-studies-evidence_research.pdf
    December 01, 2010 - Proportion of Completed Studies Among All Eligible Studies That Were Registered in ClinicalTrials.gov … In July of 2010 ClinicalTrials.gov listed nearly 95,000 studies and ISRCTN listed over 9,000 studies … All relevant studies of pharmacological treatments for dementia, 99 percent of the relevant studies … for the NIH sponsored studies. … studies is not as straightforward.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
    May 19, 2020 - • Animal studiesStudies with patients under 18 years of age • Mixed population - Less than … studies that do not report the outcomes of interest … Studies of Interventions (ROBINS-I tool). … We will conduct meta- analyses when there are sufficient data (at least two studies) and studies are … RCTs and other intervention studies with a comparison group will be analyzed separately.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - These evidence gaps can inform future research studies, the findings from which can improve clinical … Interventions • Studies of high THC to CBD ratio products derived from whole-plant cannabis, with … • Only a small number of studies have evaluated opioids. … • Studies in underserved populations and equity in program delivery. … • Studies comparing programs with pharmacologic treatments.
  12. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
    January 01, 2010 - These studies include: All nonexperimental studies Cohort, case-control, cross-sectional studies We present … Observational Studies Observational Studies Now that we have identified why observational studies should … In other words, all nonexperimental studies are observational studies. … studies. … studies.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
    January 01, 2010 - These studies include: All nonexperimental studies Cohort, case-control, cross-sectional studies We present … Observational Studies Observational Studies Now that we have identified why observational studies should … In other words, all nonexperimental studies are observational studies. … studies. … studies.
  14. effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
    November 01, 2020 - • Studies showed no difference in effectiveness between different doses or routes of administration … Strengths and Limitations We identified numerous studies evaluating a variety of nonpharmacological … However, sample sizes were small, followup was short term, most studies only used visual analog scales … Most studies included patients with lung cancer and chronic obstructive pulmonary disease, but we were … Opioids and anxiolytics were not effective, although studies were limited, and few studies evaluated
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
    May 01, 2013 - If such studies were not available, we included cross-sectional studies and intervention series studies … (6 studies). … (7 studies). … (5 studies). … 4 studies).
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-disposition-comments.pdf
    May 22, 2023 - representativeness of the populations studies. … Vitamin C studies do not provide great profits. … We suspect that observational studies are likely to face similar challenges. … We note the role of observational studies in future work in the discussion. … We suspect that observational studies are likely to face similar challenges.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
    January 09, 2020 - meta-analyses (used for identifying additional studies) In vitro studies, non- original data … ) studies, before-after studies, survey Publications Studies published in English only. … Studies included by either reviewer will be retrieved for full-text screening. … We will evaluate heterogeneity between studies using I2 indicator. … vs. estimates derived from studies at low risk of bias; or 2) when all the available studies (in a
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-evidence-heart-disease.pdf
    October 01, 2022 - Thirteen studies (3 RCTs and 10 PSM studies) were included in the meta-analysis with a total of 18,855 … Three included studies comparing PCI to OMT reported CV mortality and 15 included studies reported MI … Twelve studies (3 original RCTs, 1 long-term extension of an RCT, and 8 observational studies) were … Non-randomized studies, observational studies, and studies of non-CTO lesions or treatment with CABG … Included Studies: Three RCTs (DECISION-CTO, EUROCTO, REVASC); 14 observational studies.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
    January 01, 2016 - and 19 retrospective cohort studies, 2 diagnostic accuracy studies (defined as studies that compared … to RCT studies only. … Six comparative studies addressed timolol (two RCTs and four cohort studies). … Studies of Surgical Treatment Few comparative studies addressed surgical approaches. … ≤5% of children in 6 studies.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-disposition-comments.pdf
    October 29, 2021 - o Results: We clarified the distinction between the number of articles and studies. … We further clarified the definition of “serious mental illness” used in specific studies. … evaluated the rigor of these studies. … In relation to intervention studies, we added the concern that these studies were generally not designed … We didn’t find studies with a reference to that role.

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