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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ongoing-studies-evidence_research.pdf
December 01, 2010 - Proportion of Completed Studies Among All Eligible Studies That Were Registered
in ClinicalTrials.gov … In July of 2010 ClinicalTrials.gov listed nearly 95,000 studies and
ISRCTN listed over 9,000 studies … All relevant studies of pharmacological treatments for dementia, 99 percent
of the relevant studies … for the NIH sponsored studies. … studies is not as straightforward.
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effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
January 01, 2010 - These studies include:
All nonexperimental studies
Cohort, case-control, cross-sectional studies
We present … Observational Studies
Observational Studies
Now that we have identified why observational studies should … In other words, all nonexperimental studies are observational studies. … studies. … studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
January 01, 2010 - These studies include:
All nonexperimental studies
Cohort, case-control, cross-sectional studies
We present … Observational Studies
Observational Studies
Now that we have identified why observational studies should … In other words, all nonexperimental studies are observational studies. … studies. … studies.
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effectivehealthcare.ahrq.gov/products/methods-guidance-bias-individual-studies/methods
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - If such studies were not available, we included
cross-sectional studies and intervention series studies … (6 studies). … (7 studies). … (5 studies). … 4 studies).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
January 01, 2016 - and 19 retrospective cohort
studies, 2 diagnostic accuracy studies (defined as studies
that compared … to
RCT studies only. … Six comparative studies addressed timolol
(two RCTs and four cohort studies). … Studies of Surgical Treatment
Few comparative studies addressed surgical approaches. … ≤5% of children in
6 studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
May 01, 2017 - Seven studies addressed variations of the gluten-free diet,
but studies addressed different outcomes … The methodologic rigor of studies has increased
substantially compared with those studies reported in … While seven studies addressed variations of
the gluten-free diet, studies addressed different outcomes … We did not
conduct a de novo search for such studies but re-examined
the excluded studies from the … Harms reporting varied across studies; some studies
amply described how harms were tracked, while others
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - studies of nonhuman subjects. … Europe combined (92 studies). … than studies with a contrast rate <3 ml/s (0.71; 95% CI, 0.50 to -0.85; 4
studies). … 7 studies) than studies without
delayed phase imaging (0.74; 95% CI, 0.66 to 0.87; 7 studies). … (2 studies).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
April 01, 2015 - We excluded 844 studies at full-text review and
included 68 unique studies (76 publications) in the … (5 studies), embolization (19 studies), uterine compression
sutures (3 studies), uterine and other … pelvic artery ligation
(5 studies), embolization and hysterectomy (1 study),
hysterectomy (8 studies … Four studies
of rFVIIa reported on thrombotic events, but sample
sizes were small and studies were … 4 RCTs, 2 prospective and 14
retrospective cohort studies, 10 pre-post studies (studies
that compare
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - studies) (KQ1-6)
• Harms: Comparative studies (RCTs, prospective or retrospective cohort studies with … cohort studies had high risk. … studies. … studies and no significant
group differences in two studies. … in comparative studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
July 01, 2010 - Studies
The search strategy identified 5,677 citations; 137
unique studies met the eligibility criteria … The studies included 27 trials,
39 cohort studies, and 71 uncontrolled studies. … Results of Included Studies
The results of the included studies are presented by the
key question(s) … A total of 113 studies examined the
effectiveness of operative interventions, while 11
studies evaluated … The majority of
surgical studies (32 comparative studies and 58
uncontrolled studies) evaluated operative
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - single-arm studies or retrospective
studies enrolling consecutive patients. … Only 1 of 25 studies (4 percent)
reported including patients with occlusions in other
areas and 6 studies … of 25 (68 percent) studies. … System studies. … Compared to previous, similarly designed studies of
these agents, these studies will enroll much larger
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - The remaining studies were
cohort studies of different interventions. … These
studies would directly address Key Question 1. No published studies qualify for Tier I. … II studies. … Search and selection of studies for review
Medical treatment studies included
(n=4 studies; 5 articles … studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
October 01, 2012 - Since there are high-quality studies in this field, we
excluded all retrospective and uncontrolled studies … For most studies, this was
usual health care, but some studies tested interventions that
were added … All
seven studies were RCTs. … (2 studies). … We identified few studies in hospice
populations and no studies focusing on reducing disparities
in
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
January 01, 2012 - Further, no two studies used exactly the same mode of
additional support, and even the studies that … There were no studies in children. … across studies.
14
Table A. … • Conclusion: The evidence is weak due to inconsistency across studies or poor-
quality studies … Moderately rated bodies of evidence contain fewer than 2 quality A studies or such studies lack long-term
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - Eighteen studies pertain to KQ1a, 2 studies to
KQ1b, 14 studies to KQ2, 26 studies to KQ3, 23 studies … to KQ4, and 11 studies to KQ5. … Modifiers of Treatment
Twenty-three studies reported modifier data, including
18 imaging studies (1 … studies and draw
Table D. … Research Gaps
Although a number of studies are available on US
and MR approaches, very few studies
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
October 01, 2006 - , all 25 angioplasty studies, all 4
medical studies, 2 natural history studies, and 2 surgical
cohort … studies reported blood pressure outcomes. … Natural history studies
Associations between baseline variables and outcomes
in natural history studies … Mortality Weak • 1 RCT, 3 nonrandomized comparative studies, and 31 cohort
studies of various interventions … Angioplasty N/A • 5 comparative studies and 15 cohort studies analyzed baseline
variables as possible
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_executive.pdf
November 01, 2009 - Out of 243
papers, 185 were single-arm retrospective studies, and
another 35 studies were prospective … Seven studies (3 percent) focused
on a pediatric population; most of the remaining studies
reported mean … Two studies had mean
followup longer than 10 years. … studies (46 percent), cancer specific
survival; and 210 studies (86 percent), other surrogate
outcomes … photon
radiation for other cancers (six studies); surgery (three
studies).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - Thus we grouped
studies into two categories: (1) studies that explicitly
reported that more than 15 … new
studies for Key Questions 1, 2, and 3 respectively), for a
total of 316 included studies. … We synthesized information on adverse events from a total
of 144 studies (70 new studies and 74 from … We a reviewed a total of 143 studies for Key Question 3
(59 new studies and 84 studies from the original … of relevant studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_executive.pdf
March 31, 2010 - Studies identified in the gray literature search had to meet
the same inclusion criteria as studies … assess the risk
of bias in the included studies.13 We categorized the studies
as having low, moderate … Six
studies addressed KQ6. … )
KQ1=110 (104 studies)
KQ2 = 6 (6 studies)
KQ3 = 1 (1 study)
KQ4 = 5 (4 studies)
KQ5 = 9 (9 studies … Studies With High Statistical Power
We need more studies with large sample sizes and
adequate length