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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-disposition-comments.pdf
    April 24, 2019 - We did not exclude any studies based on condition, and w ould not exclude studies about hearing impairment … Similarly, four studies have demonstrated impact on hospitalization. … There may have been important early studies that guided future research. … We w ould ask the authors to review these studies again. … We included f ive of the eight studies included in the Kumar review .
  2. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
    February 16, 2016 - We will include studies published in English only. … the inclusion of additional studies is warranted).43 Eligible studies must also report one or more … We will use DistillerSR™ for screening studies. … The decision about pooling a set of studies using random effects will depend on whether the studies … This should be determined based on the design and quality of the studies, independent of the studies
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
    June 16, 2010 - Ongoing studies and interim analyses. Sources of Full text publications. … Studies on patients with myelodysplastic syndrome or acute leukemia. … Inclusion criteria for observational studies are as above except for “Types of studies.” … New studies will be evaluated against inclusion/exclusion criteria in the same manner as all other studies … Criteria for Inclusion/Exclusion of Studies in the Review B.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
    April 01, 2015 - We excluded studies of pediatric MS patients, studies of mitoxantrone (since it has a maximum lifetime … Risk-of-Bias Assessment of Individual Studies The risk of bias of eligible studies was assessed by two … Of the remaining 38 articles comprising 27 unique studies, only 16 studies contained complete information … Harms reported from unique studies included in the analytic set DMT Number of Studies; Total N; … Studies reporting reasons for discontinuing medication DMT Total Number of Studies Adverse Event
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
    May 22, 2012 - These studies vary from small and large nonrandomized, single-center studies to randomized, prospective … , but also by including the results of other studies, such as prospective cohort studies and comparative … These studies had the least bias, and the results were considered valid. … These studies had significant flaws that might have invalidated the results. … studies with ≥ 100 patients will also be considered.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
    April 25, 2013 - these studies. … studies (e.g. … Important studies missing? … Important studies missing? KQ2: These studies rely heavily on SSc and liver disease. … Few studies of IPAH.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
    September 25, 2013 - Most studies genotyped and analyzed one of these variants and not the other while other studies have … ); VerifyNow P2Y12 (28 studies); the vasodilator-stimulated phosphoprotein (VASP) assay (14 studies … ); Multiplate analyzer (12 studies); and Platelet Function Analyzer-100 (8 studies). … Unfortunately, this information is usually based on studies of healthy volunteers, or studies that … Were such studies actually identified?
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
    July 21, 2014 - and cohort studies. … For all KQs we will exclude uncontrolled observational studies, case- control studies, case series, and … case reports, as these studies are less informative than studies with a control group. … Sources of funding for all studies will also be recorded. … We will not exclude studies rated as being high risk of bias a priori, but high risk of bias studies
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
    January 01, 2013 - in the CER, and some studies had no control or comparison group. … The few new studies we identified supported the conclusions of the original CER. … No new studies identified. NA EPC investigator did not know. … No observational studies met the eligibility criteria. … No observational studies met the eligibility criteria.
  10. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
    February 17, 2016 - The 2012 report included studies published from 1980 through May 2011. … There were few studies evaluating the new factor Xa inhibitors. … We evaluated the number and characteristics of studies—including RCT, nonrandomized comparative studies … We will explore subgroup differences within (and possibly across) studies. … "[Mesh] OR (case and control) OR "Clinical Studies" [Publication Type] OR "Clinical Studies as Topic
  11. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
    May 01, 2005 - For some studies, all outcomes may have the same sources of bias; for other studies, the sources of … clinical trials, prospective or retrospective cohort studies, and case-control studies) in the ROBINS-I … It excludes case studies, case series and cross-sectional studies, although some systematic reviews … dIncludes nonrandomized controlled studies with investigator-allocated treatment and observational studies … or a body of studies.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
    September 29, 2014 - The characteristics of the studies are clearly described. … Not aware of any additional studies that ought to have been included studies that ought to have been … Indeed for some questions, no studies met the criteria. … However, there is a need for published studies evaluating the effectiveness of risk mitigation studies … Indeed for some questions, no studies met the criteria.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_disposition-comments.pdf
    August 23, 2013 - We note these studies in the discussion. … Eligibility of studies was not based on the methodological quality of studies. … Eligibility of studies was not based on the quality of studies. … studies are flawed. … The studies are not independent as several studies had multiple treatment arms.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
    August 07, 2018 - and high risk of bias studies. … the lithium studies) were longer. … We have noted when maintenance studies were extensions of short-term studies for acute episodes. … Moreover, 14 studies had small sample sizes of less than 200 participants and 21 studies (79 percent … I note that the authors explicitly INCLUDED studies with time to relapse as an outcome, and studies
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-protocol.pdf
    April 01, 2014 - Have any of these studies shown improvements in quality of care, improvements in health outcomes, or … If no such studies of children are available, what studies have assessed whether specific equivalent … We will also hand search the included studies of previous relevant reviews and consult with our Key … Comparisons: We plan to include studies that have comparisons of different interventions or measures … selection criteria, or standard appraisal of studies.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
    January 01, 2014 - 3 studies comparing at least 2 different surgical interventions,54-56 and 11 studies evaluating a surgical … We included studies without a comparison group because we anticipated finding few comparative studies … Three studies compared two surgical techniques.54-56 We also included 11 studies that evaluated a surgical … We expanded our review to include observational studies, but these studies were largely limited to convenience … Among the studies we identified, we found a general lack of well-designed, well-controlled studies,
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
    March 01, 2012 - do not apply to most studies that assess adherence. … treatment at 1 year, with adherence ranging widely across studies … No studies describe primary nonadherence (i.e. nonfulfillment). … Newcastle- Ottawa Quality Assessment Scale, Cohort Studies. … Quality Assessment Scales for Observational Studies. 2004. 19.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
    April 30, 2014 - , and reviews studies in progress germane to the topic. … of studies. … Please note that we were referring to study arms (not studies). … Regarding the studies by Zmora and Bucher: we decided to include them with studies using enemas for … Do we know why they were excluded (e.g. non-surgical studies)?
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
    November 20, 2014 - that directly compared imaging studies. … When studies are big, smaller difference between studies could be detected along with a higher I2 value … studies only evaluating single modalities. … Of note is the fact that the AHRQ report included only studies on PET/CT, thereby excluding older studies … We suggest assessing the following studies for possible inclusion, as these studies were included by
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
    August 16, 2016 - and non-randomized comparative studies. … but excluding PTRAS or medical management studies. … The comparative studies section has separate sections for RCTs and nonrandomized studies. … It was agreed upon to restrict the review of PTRAS cohort studies to prospective studies. … studies.

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