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  1. effectivehealthcare-admin.ahrq.gov/products/telehealth-women/protocol
    January 01, 2023 - (non-RCT with some type of comparison): Comparative studies including trial and observational studies … ) Qualitative studies that evaluate preferences, barriers/facilitators Studies that specifically note … For the key questions we will exclude descriptive studies with no outcome data or studies that include … We will also exclude modeling studies or studies that use synthetic data. … Applicability of Individual Studies: Applicability of individual studies will be considered according
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - Decision To Combine Studies The decision to combine studies to produce an overall estimate should depend … Clinical and methodological diversity among studies always exists even if a group of studies meet all … When the sizes of the included studies are small, it would take a substantial number of studies to … Combining studies of mixed designs. … excluding such studies. 7.
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
    March 01, 2014 - Overall, we included 121 studies represented by these 115 publications: 78 studies were relevant to … Nineteen studies in KQ 1 (23%) and 3 studies in KQ 2 (6%) included children. … Seven studies were RCTs, and the remaining 71 were observational studies. … Thirty-three of the 48 studies were parallel-group RCTs, and 12 were randomized crossover studies. … studies of 59 individual agents.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - Decision To Combine Studies The decision to combine studies to produce an overall estimate should depend … Clinical and methodological diversity among studies always exists even if a group of studies meet all … When the sizes of the included studies are small, it would take a substantial number of studies to … Combining studies of mixed designs. … excluding such studies. 7.
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
    October 12, 2016 - (Comments pertain to the maternal studies more than the child studies.) … Studies of n-3 FA alone were included as were studies of n-3s plus n-6s. … The list of studies is comprehensive and doesn't include studies that should have been excluded. … to the studies we could include. … studies.
  6. effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases/protocol
    August 01, 2022 - studies NRSI for effectiveness if RCTs are available Studies with <10 patients per arm Single … arm studies (unless no comparative studies); if used, exclude studies of <10 patients Case reports … In the absence of comparative studies, single arm (e.g., case series, pre-post studies) with at least … We will focus on primary studies and review systematic review (SR) references for relevant studies as … from poorer-quality studies.
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
    May 01, 2013 - Quality Assessment of Individual Studies We evaluated the quality of individual studies by using the … Six studies (four RCTs, two observational studies) reported variations in the treatment effectiveness … Subgroups reported included age (three studies), symptom class (three studies), renal failure (two studies … ), arterial outflow/runoff (two studies), anatomic factors (two studies), type of vein graft (two studies … IC-CLI-Obs (3 studies, 563,935 patients) IC-CLI-RCT (2 studies, 130 patients) Inconclusive evidence
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
    January 01, 2023 - To streamline data extraction, we will sort eligible studies by specific PSP (if the report covers … Risk of Bias Assessment For studies that address the Review Question about the effectiveness of PSPs … criteria, or standard appraisal of studies. … ROBINS-I: A tool for assessing risk of bias in non-randomised studies of interventions. … Criteria for assessing internal validity of individual studies [Internet]. Rockville (MD): U.S.
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
    March 22, 2021 - at all, and that some studies conducted subgroup analysis on this variable and others did not. … These studies could compare surveillance methods or to no monitoring. … We initially hoped to be able to conduct subgroup analyses based on US vs. non-US studies. … Ultimately, we did not have enough studies for a given comparison to do that. … Removing all non-US studies would lead to insufficient evidence across the board.
  10. 8 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
    November 01, 2008 - Observational Studies Observational studies are almost always necessary to assess harms adequately … Other observational studies. … Two studies found that industry- funded studies tended to report more favorable outcomes than did studies … types of studies. … Review Studies meet certain study design definitions (e.g., cohort and case-control studies) Studies
  11. 8 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - Observational Studies Observational studies are almost always necessary to assess harms adequately … Other observational studies. … Two studies found that industry- funded studies tended to report more favorable outcomes than did studies … types of studies. … Review Studies meet certain study design definitions (e.g., cohort and case-control studies) Studies
  12. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
    July 01, 2011 - The two studies of cardiovascular mortality did not have consistent findings, and the two studies of … Overall, the studies were clinically heterogeneous, small, and of quality B (three studies) or C (two … studies). … Treatments • Only 3 of the 190 studies of treatments reported clinical outcomes; comparative studies … Only 3 of 7 studies found increased number of hours of CPAP use; only 1 of 3 studies found persistent
  13. effectivehealthcare-admin.ahrq.gov/products/economic-evidence/research
    November 01, 2017 - Methods The review included original studies that applied a quantitative or qualitative method for … Results Of 19,127 titles initially screened, 43 studies were included, with all but five published … Most studies (27 studies) considered national-level policy and examined the key health actors involved … In two studies, economic evidence had no impact on health policymaking. … evidence (17 studies).
  14. effectivehealthcare-admin.ahrq.gov/products/long-term-care-adults/research-protocol
    December 01, 2019 - Studies published in English. … Studies from 1995-current. … Non-English language studies. … Studies that do not have a direct comparison between NH and HCBS (e.g., studies that compare one type … and studies that report casemix.
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
    August 01, 2016 - Observational Studies, Intake Seven studies evaluated total n-3 FA intake. … studies), CHD death (3 of 7 studies), MI (1 of 2 studies), incident CHF (1 of 5 studies), and AFib … (1 of 3 studies). … ), CVD (3 studies), MACE (2 studies), hemorrhagic and ischemic stroke (2 studies each), AFib (1 study … total stroke (2 studies each), MACE (2 studies), all-cause death (2 studies), or AFib, SCD, incident
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - epidemiologic studies—STrengthening the Reporting of OBservational studies in Epidemiology (STROBE … two quality A studies, a low rating involves quality B or quality C studies, and an insufficient rating … Few studies were designed a priori as studies of diagnostic- test performance with an adequately powered … The eight reviewed studies of patients with MM were mostly retrospective cohort studies, and only three … or of cohort studies in this area.
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
    February 01, 2013 - Little disagreement exists across studies. … Underlying studies may report conflicting results. … The majority of the patients in these studies were men, and the reviewed studies specifically excluded … We were not able to conduct meaningful subgroup analyses stratifying older versus newer studies (studiesstudies.
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preoperative-testing_executive.pdf
    January 01, 2014 - , and cohort studies. … surgeries (37 studies), tonsillectomy (5 studies), cataract surgery (4 studies), orthopedic surgery … (4 studies), vascular surgery (3 studies), head and neck/ear, nose, throat surgery (2 studies), and … Forty studies were published before 2000, including 7 of the 14 comparative studies; 17 studies were … Cohort Studies Given how few comparative studies were available, we looked at cohort studies to test
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
    August 01, 2012 - The studies included 121 RCTs, 2 nRCTs, and 2 retrospective cohort studies. … Overall, 113 studies examined schizophrenia or schizophrenia-related psychoses, 11 studies examined … Placebo-controlled studies or studies comparing an FGA versus another FGA, or an SGA versus another … there were few studies. … Almost half the studies involved hospitalized patients (inpatient treatment) (62 of 125 studies) or
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
    July 24, 2013 - Case-control studies, case studies, literature reviews Studies that do not report sensitivity, cost … , and other observational studies. … Case-control studies, case studies, literature reviews Studies that do not report sensitivity , cost … Case-control studies, case studies, literature reviews Studies that do not report sensitivity , cost … ) • Studies of treatment response • Studies looking at liver metastases • Studies with imaging conducted

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