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effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-screening/research
December 01, 2019 - Initial validation studies were excluded due to their use of highly selected patient populations. … Sensitivity for advanced adenomas was similarly low in both studies. … We found no studies that specifically evaluated the harms of fecal DNA testing. … While three poor-quality analytic validity studies showed that technological advances can improve the … No studies have evaluated the relative acceptability of fecal DNA tests to FIT tests.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/worker-health_executive.pdf
April 01, 2016 - , and pre-post studies. … We included 24 studies described in 33
publications.10,11,20-50 Of the 24 included studies, 15
studies … Most studies had high
overall attrition (ranging from 14% to 45%); many
studies had differential attrition … The 15 KQ 2 studies were quite different; few
studies of TWH interventions assessed the same
outcomes … Overall attrition was high in several studies;
most studies performed a complete-case analysis;
participants
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effectivehealthcare-admin.ahrq.gov/products/nonpharma-treatment-pain/research-protocol
December 01, 2019 - All KQs:
Studies reporting on intermediate outcomes only
Nonrandomized studies
Abstracts, editorials … We will exclude cohort studies, case-control studies, case reports, and case series. … than higher quality studies when synthesizing the evidence, particularly if discrepancies between studies … from poorer-quality studies. … Random effects across studies are assumed and if estimates across studies vary widely, profile likelihood
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effectivehealthcare-admin.ahrq.gov/products/mass-casualty-events-scarce-resources/research
April 01, 2020 - We included both English- and foreign-language studies. … Twenty-seven studies focus on strategies for policymakers. … The review includes 119 studies that address strategies for providers. … Only 10 studies included strategies that consider the public's perspective. … However, these studies were consistent in their findings.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-applicability.ppt
June 01, 2012 - Assessing applicability of medical test studies in systematic reviews. … for Inclusion
Search for Studies
Extract Data From Studies
Analyze and Synthesize Studies
Assess … Studies are not specific to the key questions
Studies may not reflect the subgroups or comparisons identified … Excluding studies with older technologies and presenting results of included studies by slice thickness … of test used in practice and in studies
How and by whom tests are conducted in practice and in studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-applicability.ppt
June 01, 2012 - Assessing applicability of medical test studies in systematic reviews. … for Inclusion
Search for Studies
Extract Data From Studies
Analyze and Synthesize Studies
Assess … Studies are not specific to the key questions
Studies may not reflect the subgroups or comparisons identified … Excluding studies with older technologies and presenting results of included studies by slice thickness … of test used in practice and in studies
How and by whom tests are conducted in practice and in studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-evidence-summary.pdf
January 01, 2020 - Included
studies for KQ 1 had to have a concurrent control group
or (for single-group pre-post studies … Of the KQ 2 included studies, 18
were studies from a prior 2007 AHRQ review addressing
the maternal … States (2 studies);39, 40 Taiwan (2
studies);46, 50 and one each in the Republic of Belarus,37
Hong … countries (6 studies).53, 56, 57, 60, 62, 63 Studies
assessed a variety of intervention types; the … with >1,500 women, 31 studies with 500-1,499 women, and 15 studies with <500 women.
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effectivehealthcare-admin.ahrq.gov/products/child-obesity-future/research
December 01, 2019 - The draft Comparative Effectiveness Review evaluated 96 intervention studies reported in 113 articles … Only a few studies that we reviewed used social marketing to deliver messages on nutrition, physical … There were methodological limitations of the reviewed studies which suggest that future research might … why some studies might detect desirable effect of the intervention. … example, studies using a community-based participatory approach.
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effectivehealthcare-admin.ahrq.gov/products/chronic-pain-opioid-treatment/research
December 01, 2019 - We also included uncontrolled studies ≥1 year that reported rates of abuse, addiction, or misuse, and … Results
Of the 4,209 citations identified at the title and abstract level, a total of 39 studies were … For a number of Key Questions, we identified no studies meeting inclusion criteria. … were 3.1 percent to 26 percent in primary care settings, but studies varied in methods used to define … study), with several studies showing a dose-dependent association.
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effectivehealthcare-admin.ahrq.gov/products/weight-loss-surgery/research
December 01, 2019 - The following studies were excluded: (1) those with no outcomes of efficacy, effectiveness, or safety … /adverse events; (2) nonsurgical studies with less than one year followup; (3) nonsurgical studies already … included in previous systematic reviews; and (4) studies with a sample size of less than three. … Due to the dearth of long-term studies of bariatric surgery in this particular target population, few … The strength of evidence for BPD is rated low because there are fewer studies, and these have smaller
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - of
these studies were applicable to KQ 3,16-18 and one was
applicable to KQ 2.19 Of the 94 studies … Of these 94 studies, 78 studies included sufficient
data to estimate the sensitivity and specificity … , two studies of CMR, and four studies of SPECT that reported these
predictors … 2) ECHO (6 studies), (3) SPECT (3 studies), (4) CMR (2 studies), and (5)
coronary CTA (4 studies) … noncomparative
studies.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
January 01, 2007 - studies). … year (2
studies). … all eight studies. … ), headache (21 studies), dizziness (18 studies), fatigue (10
studies), upper respiratory infection … (6 studies), and nausea (6 studies).
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effectivehealthcare-admin.ahrq.gov/products/gout/research-protocol-2014
March 01, 2020 - Criteria for Inclusion/Exclusion of Studies in the Review
Included studies will be limited to those … Finally, we will ask the TEP to assess our included studies and to provide references for any studies … Studies will be weighted by sample size. … studies that include long-term, clinical outcomes and in applying standards of precision to these studies … studies.
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effectivehealthcare-admin.ahrq.gov/products/gestational-diabetes-screening-diagnosis/research
December 01, 2019 - We conducted a descriptive analysis for all studies and meta-analyses when appropriate. … , 63 prospective cohort studies, and 28 retrospective cohort studies). … Prevalence of GDM varied across studies and diagnostic criteria: American Diabetes Association (75 g) … Only two studies examined the effects on health outcomes from screening for GDM. … Five studies provided data on harms of treating GDM.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
December 01, 2010 - Five of six testers agreed on two studies, four agreed on six studies, three agreed on two
studies, … studies, and cohort studies). … Five of six testers agreed on two studies, four agreed on six studies,
three agreed on two studies, … the studies. … studies.
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effectivehealthcare-admin.ahrq.gov/products/pressure-ulcer-prevention/research-protocol
December 01, 2019 - trials and controlled or comparative observational studies
KQ 4: randomized trials, cohort studies … Non–English-Language Studies
Non–English-language studies will be included in the searches and translated … Individual studies will be rated as “good,” “fair,” or “poor.” … We will not exclude studies rated as being poor in quality a priori, but poor-quality studies will be … if discrepancies between studies are present.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
October 01, 2016 - Studies in
the original report deemed eligible for pooling with newly
identified studies were included … Risk of bias among observational studies
was assessed using questions relevant for prospective
studies … Prospective observational studies
and biomarker studies reported inconsistent associations
between … Among studies
reporting on the same outcomes, results were often
inconsistent across studies. … Studies that labeled themselves
as studies of DHA alone often included some amount
of EPA as well as
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effectivehealthcare-admin.ahrq.gov/products/masks-covid/protocol
February 01, 2021 - Systematic reviews will be used to identify relevant primary studies. … Studies will be stratified according to setting (healthcare versus community). … For studies conducted in the community, we will stratify studies according to whether the mask is worn … studies were in the original review. … Criteria for Assessing Internal Validity of Individual Studies . 2017.
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effectivehealthcare-admin.ahrq.gov/products/prosthesis/research-protocol
January 01, 2019 - in these studies; 4) assess the strength of evidence for studies of differential comparative effectiveness … What are the characteristics of the participants in these studies? … What are the characteristics of the participants in these studies? … Any comparative studies (KQ 4) or long-term followup studies (KQ 7) found from existing systematic reviews … studies and descriptions of statistical significance of studies, emphasizing larger studies with better
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-1.pdf
July 01, 2019 - , not diagnostic, individual-level, or
observational studies
Background
• Quantitative synthesis … be combined with cluster-
randomized studies? … ► Cherry-picking studies to include in meta-analysis can introduce
bias. … The Impact of Study Size on Meta-analyses: Examination of Underpowered Studies in Cochrane Reviews. … The Impact of Study Size on Meta-analyses: Examination of Underpowered Studies in Cochrane Reviews.