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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - Observational studies
include cohort studies with or without a comparison group, cross-sectional studies … This is particularly
important in case-control studies, where subjects are entered into studies based … If these studies address all
important aspects of the review questions, then observational studies may … Includes
sample size, number of studies, and
heterogeneity within or across studies. … Selecting Observational Studies for Comparing Medical Interventions
Selecting Observational Studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
June 01, 2010 - Observational studies
include cohort studies with or without a comparison group, cross-sectional studies … This is particularly
important in case-control studies, where subjects are entered into studies based … If these studies address all
important aspects of the review questions, then observational studies may … Includes
sample size, number of studies, and
heterogeneity within or across studies. … Selecting Observational Studies for Comparing Medical Interventions
Selecting Observational Studies
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-bias-individual-studies/methods
October 01, 2019 - as studies with high risk of bias. … newer studies may appear to be biased when compared to older studies, because of changes in journal … studies are poor.” … experimental studies and observational studies). … (RCTs and observational studies).
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effectivehealthcare-admin.ahrq.gov/products/integrating-evidence/methods
December 01, 2019 - Recommendation : We recommend that newly identified studies be clearly distinguished from studies in … If the new studies would change the conclusions or the SOE judgments or the new studies are in some way … We recommend that newly identified studies be clearly distinguished from studies in the existing review … When is it okay not to add new studies (or conduct a search for new studies)? … Grading practices range from grading all studies using own criteria to grading the new studies and comparing
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-bias/methods
December 01, 2019 - useful to consider the range of limitations in medical test studies. … In a series of studies of bias in the context of medical test literature, Whiting et al. reviewed studies … . 1 However, medical test performance studies differ from intervention studies in that they are typically … for reporting observational studies. … Assessing risk of bias as a domain of quality in medical test studies.
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-applicability/methods
May 01, 2020 - Assessing the Applicability of Studies When Comparing Medical Interventions. … of applicability on interpretation of individual studies. … not the same as applicability of the individual studies. … Note whether studies share features that limit applicability—for example, did all the studies exclude … Setting
Describe geographic and clinical setting of studies.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
February 01, 2013 - Studies evaluating reasons for discrepancies in included studies among
systematic reviews ........ … Studies evaluating reasons for discrepancies in included studies among systematic reviews
Study Study … Quality or risk of
bias of individual
studies
Reviewer decides to exclude low
quality studies or … Studies may have measured
outcomes, but not reported them in
the studies due to null findings. … However, smaller studies or non-English
studies may be systematically different from larger studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - For studies that are ongoing but not completed, what was the date of initiation of
the studies? … Description of the Identified Studies
For the first question, we described all studies we identified … For studies that are ongoing but not completed, what was the date of initiation of the
studies? … Four studies had different reporting of the same measure.5, 12, 14, 20 In all four of these
studies, … Six studies evaluated 0.75%
capsaicin topic cream and two studies evaluated 8% capsaicin patch.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
March 01, 2012 - as studies with high risk of bias. … newer studies may appear to be biased when
compared to older studies, because of changes in journal … studies are poor.” … nonrandomized experimental studies and observational studies). … (RCTs and observational studies).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
February 01, 2015 - Recommendation: We recommend that newly identified studies be clearly distinguished from
studies in … If the new studies would change the conclusions or the SOE judgments or the
new studies are in some … We recommend that newly identified studies be clearly distinguished from studies in the existing review … When is it okay not to add new studies (or conduct a search for new studies)? … Grading practices range from grading all studies using own criteria to grading the new studies and comparing
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - Choice of Statistical Model for Combining Studies
Quantitative Synthesis
Chapter 3. … Choice of Statistical Model for Combining Studies
Prepared for:
The Agency for Healthcare Research and … .
− Therefore differences between studies’ treatment effects are due to random variability … • When a systematic review includes small and large studies, and
results of small studies are different … ► For studies with zero events in one arm, or studies with sparse binary data
but no zero events,
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
January 01, 2012 - of net benefit given the costs of studies. … , and similarity of included studies. … Included studies of sufficient validity and quality
4. … Insufficient data: too few primary studies, or studies that are too small (sample size inadequate or … The use of
systematic reviews when designing studies.
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effectivehealthcare-admin.ahrq.gov/products/attention-deficit-hyperactivity-disorder/research
November 01, 2024 - We included 550 studies reported in 1,097 publications (231 studies addressed diagnosis, 312 studies … This included 230 studies addressing diagnosis (KQ1), 311 studies addressing treatment (KQ2), and 10 … in the studies was 25 percent. … NOTE: The number of studies listed below includes all studies that met our inclusion criteria for the … n=561); methylphenidate studies favored intervention (SMD 0.66; 0.04, 1.28; 2 studies, n=302); NRI studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/reliability-testing-grading-evidence_research.pdf
May 01, 2012 - through both RCTs and observational studies;
limited information in studies, such as the inclusion … a
(Total N across
studies)
Observational
Studies
Number of
Studies
(Total N across
studies … a
(Total N across
studies)
Observational
Studies
Number of
Studies
(Total N across
studies … Observational Studies
Across the six exercises that included observational studies, agreement among … Observational Studies
Exercises evaluating the consistency of outcomes based on observational studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
March 01, 2024 - We reported the range of reported diagnostic performance for
diagnostic studies; treatment studies were … This included
231 studies addressing diagnosis (KQ1), 312 studies addressing treatment (KQ2), and 10 … studies addressing monitoring (KQ3). … in the studies was 25 percent. … CI 0.05, 0.96; 10
studies, n=1703; moderate SoE).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-executive-summary.pdf
February 01, 2025 - Results
We included 187 studies (KQ1: 179 studies, KQ2: 9 studies, and KQ3: 5 studies).
KQ1. … that addressed this KQ, 149 studies enrolled only EMS
clinicians, 24 studies enrolled only telecommunicators … (798 participants total) that addressed this KQ, seven studies
enrolled EMS clinicians and two studies … total) addressed this KQ, including three studies that
enrolled EMS clinicians and two studies that … /self-harm (9.5% to 24.4%)
0 studies
Substance use Routine practice Insufficient evidence 3 studies
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-268-racial-disparities-health-healthcare-executive-summary.pdf
December 01, 2023 - screening (3 studies), and determine eligibility for prostate cancer
screening (2 studies). … • KQ 1 studies found that algorithms may reduce racial and ethnic disparities (5
studies), perpetuate … Fourteen studies addressed KQ 1, 41
studies addressed KQ 2, and 3 studies addressed both KQs and are … ROB was rated as Low for 8
studies, Moderate for 31 studies, and High for 5. … 3 studies).
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effectivehealthcare-admin.ahrq.gov/products/improved-cancer-outcomes/research
May 01, 2024 - with few studies conducted within the U.S. setting. … Among studies included in our Key Questions, few (4%, n=8) studies reported a formal evaluation of the … Eligible studies included randomized controlled trials (RCTs) with enrollment ≥50 participants. … We extracted basic study information from all eligible studies, then grouped studies by broad intervention … Few studies were conducted within the U.S. setting.
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effectivehealthcare-admin.ahrq.gov/products/genitourinary-syndrome/research
March 01, 2025 - the KQ2 and KQ3 studies, respectively. … All remaining studies included at least 80% white participants and over a quarter of total studies included … Less than one-third of studies included over 100 participants per arm (only 6 studies had n=200-380 participants … Finally, many studies, especially studies of energy-based interventions, recruited women from specialty … be supplemented with observational studies.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024_0.pdf
January 01, 2024 - Studies, Overall Studies Included in the
Evidence Tables
20
Most studies enrolled both female and … Studies, Overall Studies Included in the
Evidence Tables
23
Some studies targeted specific types … Characteristics of Included Studies, Studies Added in This Update
43
Five studies limited inclusion … , Studies Added in This Update
45
Most studies (78%, 42 studies) used a self-report measure to assess … Summary of PTSD and other outcomes for newly included studies
Outcome N studies % of studies
PTSD