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www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-1996
January 01, 1996 - disease and its treatment — surgical resection, colostomies, chemotherapy, and radiotherapy — can produce significant … over 840,000 patient-years of follow-up, a family history of colorectal cancer was associated with a significant … persons with colonic polyps discovered on routine sigmoidoscopic examination will not develop clinically significant … colonoscopy), procedures that are costly, anxiety provoking, and potentially harmful, are unlikely to be of significant … economic implications associated with the widespread performance of FOBT and sigmoidoscopy are clearly significant
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-1996
January 01, 1996 - screening in the general population may be made on other grounds, such as the low prevalence of clinically significant … available in any population, clinicians may decide to screen selected high-risk patients, due to the significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/MLeu_yFpPwzcZwKG6fw5ZY
April 26, 2022 - Although statistically significant associa-
tions with CRC incidence were found in selected analyses … In addition, a recent aspirin trial in older adults,
ASPREE, found a significant increase in CRC mortality … The updated systematic review confirmed no significant asso-
ciation of low-dose aspirin with CVD mortality
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening
August 21, 2018 - relative ratio of CIN 3+ detection between the 2 strategies (cotesting vs cytology alone) were not statistically … significant after 2 rounds of screening. … results reported lower sexual satisfaction regardless of their cytology results, but there were no statistically … extending screening beyond age 65 years in women with an adequate screening history would not have significant … Cotesting may detect slightly more cases of CIN than screening with hrHPV testing alone but with a significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TAgAUJ5QoaRfV3M8fApBoN
June 03, 2019 - The reduction was statistically significant in
only one of these trials (the Swedish Two-County Trial … trials suggest a
benefit (risk reduction, 13% to 42%), and one (the Goth-
enburg trial) observed a statistically … significant risk reduc-
tion since 1996. … significant (6, 52, 86). … Significant reduction in ad-
vanced breast cancer.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6fFns4N2J-t5EGC5BUdRuu
October 23, 2023 - Although treatable, HIV is not curable and has significant health
consequences. … At 96 weeks, TAF/FTC was associated with a statistically
nonsignificant decreased risk of HIV acquisition … TDF/FTC and teno-
fovir disoproxil fumarate alone were associated with a statistically non-
significant … In the 1 open-label trial, there was also no statistically signifi-
cant association between PrEP and
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
August 22, 2023 - Latino persons, and 26% among White persons in 2020. 3 Although treatable, HIV is not curable and has significant … At 96 weeks, TAF/FTC was associated with a statistically nonsignificant decreased risk of HIV acquisition … TDF/FTC and tenofovir disoproxil fumarate alone were associated with a statistically nonsignificant increased … In the 1 open-label trial, there was also no statistically significant association between PrEP and the
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvDjnZzW9PDxzKBauB4QxA
August 21, 2018 - aged 25 to 65 years, evidence was consistent in
demonstrating that primary hrHPV screening led to a statistically … years follow-up on
the first screening round.27-29 In 14 years of long-term follow-up,
there were no statistically … significant differences in incidence of
invasive cervical cancer among women in the intervention group … detection rates were comparable
between the intervention and control
groups for both rounds, with no
significant … findings from
1-2 rounds of screening
CIN 3+ outcomes were similar to the
overall group results, with no
significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/3HxQuXnyqHpUKNqjB7hWBw
September 01, 2005 - Harris, PhD, MPH
Background: Clinically significant mutations of BRCA1 and
BRCA2 genes are associated … Although clinically significant BRCA mutations are es-
timated to occur in 1 in 300 to 500 persons in … *Indicates clinically significant mutation of BRCA1 or BRCA2. … Deaths 1 0 NS
* DVT � deep venous thrombosis; ER � estrogen receptor; NA � not available; NS � not statistically … significant; PE � pulmonary embolism; VTE � venous
thromboembolic event.
† Calculated.
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www.uspreventiveservicestaskforce.org/uspstf/document/risk-factors-and-other-epidemiologic-considerations-for-cervical-cancer-screening-a-narrative-review-for-the-us-preventive-services-task-force/cervical-cancer-screening-2012
October 15, 2011 - Therefore, HPV testing among women aged 30 years or older may identify more clinically significant persistent … A statistically significant protective effect of screening was not demonstrated until age 32 years, when
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/aSTzfuKHZtT8_PjfJjuck5
March 01, 2013 - Intimate partner violence introduces
significant safety issues that compel a provider to be fully
informed … Although there are significant challenges in this re-
search field, additional studies are needed to … The USPSTF recognizes that a significant body of
evidence is lacking for other populations, especially … Differences for the other outcomes
were not significant (44). … Two trials reported no statistically significant harms
compared with the nonintervention groups.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/family-violence-screening-interventions-1996
January 01, 1996 - received services of an advocate for 4-6 hours per week reported better overall quality of life, but no significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Pzrh6m8vUcdvmsaBwKaQA2
February 01, 2014 - A
woman’s risk for breast cancer increases to 45% to 65% by
age 70 years if there are clinically significant … In 1 study of 90 women
who had risk-reducing bilateral mastectomy (73, 74), there
were significant reductions … in scores for anxiety and sexual
pleasure and no significant differences in depression scores,
body … In another study
(75), there were no significant differences in psychological
measures between women … After risk-reducing
salpingo-oophorectomy, premenopausal women reported
significant worsening of vasomotor
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/oral-cancer-screening-1996
January 01, 1996 - Given the significant morbidity and mortality associated with advanced oral cancer and its treatment,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ngSKuH6MP9L_BSuX-Pp2K6
January 01, 2010 - It was thus difficult
to determine whether a specific counseling
component was significant or essential … The study did not find any significant
overall group differences in self-reported physical
activity or … problems (chest pain, difficulty
breathing, dizziness or loss of consciousness) over 2
years, with no significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/sZN5HHS8w5Sar6bBPabsaB
June 01, 2008 - In the Physicians’ Health Study (71),
aspirin was associated with significant cardiovascular risk
reduction … also reduced diabetes
incidence (pooled hazard ratio, 0.65 [CI, 0.51 to 0.83]),
although the data were statistically … Studies generally showed no evidence of a significant
differential effect between diabetes and nondiabetes … Cross-sectional study: No significant differences between T2DM
population and general Swedish population … ACE-I: significant increase in cough vs. placebo.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary23/diabetes-mellitus-type-2-in-adults-screening-2008
June 15, 2008 - In the Physicians' Health Study 71 , aspirin was associated with significant cardiovascular risk reduction … also reduced diabetes incidence (pooled hazard ratio, 0.65 [CI, 0.51 to 0.83]), although the data were statistically … A diabetes population of significant interest to a screening program would be individuals who would benefit … Cross-sectional study: No significant differences between T2DM population and general Swedish population … ACE-I: significant increase in cough vs. placebo.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/PGYTn_cWQnmAr9-3du5StE
February 01, 2016 - Rates of recommenda-
tions for biopsy did not statistically significantly differ
across age groups and … by Risk Factors
False-Positive Mammography Results
Rates of false-positive mammography results were
statistically … Other comparisons between
groups were not statistically significant. … Other comparisons between
groups were not statistically significant. … family history of breast cancer,
high breast density, and previous benign breast biopsy
result) were statistically
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ffNDS7ekxovstoCxxtLJVt
February 13, 2018 - There was also no significant difference for incidence of all clinical
fractures (15.3% vs 16.0%; HR, … However, the
study reported a statistically significant reduction in hip fracture in-
cidence (2.6% vs … This study (n = 7868) evaluated treatment with deno-
sumab in women and found a significant reduction … 485).4 Evidence on bisphosphonates and cardiovascular
events is more limited and generally shows no significant … Pooled analyses showed no significant
increase in discontinuation (RR, 1.14 [95% CI, 0.85-1.52]) or serious
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
August 24, 2017 - Framework
a Clinically significant