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www.uspreventiveservicestaskforce.org/home/getfilebytoken/wBcZfBcVp8N3-cyT3Peysv
April 01, 2016 - Meta-
analysis showed a statistically significant 22% reduction
in nonfatal MI, although heterogeneity … Two trials showed a statistically
significant benefit of aspirin for reducing CVD mortality. … Further, the RR was statistically significant only
when baseline characteristics were adjusted for (odds … Of note,
the WHS (37) showed a statistically significant 34% re-
duction in total MI only among women … The 3 RCTs
showed no statistically significant stroke difference, al-
though they were underpowered for
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary24/drug-use-illicit-primary-care-interventions-for-children-and-adolescents-march-2014
March 11, 2014 - Four of the 5 trials assessing self-reported marijuana use found statistically significant differences … Only 1 of the 3 primary care–based studies found statistically significant differences in drug use at … Likewise, all 3 studies reported statistically significant reductions favoring the intervention group … The other 2 studies did not find statistically significant differences between groups. … One trial also showed a statistically significant effect for inhalant use
3 (adverse events)
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www.uspreventiveservicestaskforce.org/uspstf/document/reducing-risk-for-mother-to-infant-transmission-of-hepatitis-c-virus-a-systematic-review-for-the-us-preventive-services-task-force/hepatitis-c-screening-2013
November 15, 2012 - reported higher transmission risk after vaginal or emergent cesarean delivery, but the difference was statistically … significant in only 1 fair-quality study 19 . … One ( n = 181) reported a direction of effect that was not statistically significant but was similar … The exception was 1 small ( n = 59), poor-quality Japanese prospective cohort study that reported a statistically … for vertical transmission versus cesarean delivery, and the largest single study 15 reported a non–statistically
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
November 24, 2020 - significant for either outcome. … The pooled effect did not demonstrate a statistically significant benefit (pooled RR, 0.89 [95% CI, 0.71 … Overall, interventions involving counseling on diet and physical activity led to statistically significant … Overall, behavioral counseling resulted in small, statistically significant improvements in saturated … The pooled effect of continuous outcomes was not statistically significant (pooled standardized mean
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-nsaids-for-prevention-of-colorectal-cancer-preventive-medication-2007
March 15, 2007 - only the highest dose of aspirin (for example, 300 mg and 325 mg per day) in each study resulted in a statistically … found that moderate and high calculated cumulative dosing (.320 mg) of "any NSAID" was associated with statistically … Health Study assessed the efficacy of low-dose aspirin in decreasing colorectal adenomas and found a statistically … those of NSAIDs or placebo in individuals with active osteoarthritis or rheumatoid arthritis found a statistically … significant higher rate of clinically significant renal events for valdecoxib and NSAIDs (2% to 3%)
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/LNtA2SDWjpsDwjXvsH4F5m
April 17, 2023 - None of the trials
reported statistically significant differences across various serious
health outcomes … The difference between groups was not statistically signifi-
cant (RR, 0.79 [95% CI, 0.40-1.55]) for … Estimates of perinatal mortality were not statistically significant in
the large US trial (RR, 1.00 [ … In the large US trial, the risk of IUGR/SGA (<10th
percentile) was not statistically different between … significant (RR, 1.21
[95% CI, 0.90-1.64]).1,38,41 The risk of postpartum hemorrhage was
similar in
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/guxuobDFwkzk5YJWU5ZQkw
August 01, 2023 - The study
reported a statistically significant reduction in neural tube defects
in women taking folic … The study reported
no statistically significant differences associated with folic acid
supplementation … significant
associations between supplementation and increased risk of ASD. … Two studies reported statistically significant reductions of autism as-
sociated with folic acid supplementation … Neither reported harms;
however, 1 study reported a statistically significant reduction of ASD
associated
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/breast-cancer-screening
April 30, 2024 - significant differences in interval cancers (pooled relative risk, 0.87 [95% CI, 0.64-1.17]; 3 studies … significant for DBT vs digital mammography in the individual trials. … significant differences in the absolute risk of breast cancer mortality (0.07 fewer deaths per 1000 … No statistically significant differences were found in the cancer characteristics (tumor size, nodal … Meta-analysis of 3 large trials did not show a statistically significant difference in rates of interval
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/PR7HUFdx2b_F9HvDFqz76L
March 19, 2024 - year after the initial follow-
up, and after 1-year follow-up results were mixed; 2 trials reported
statistically … rollment) varied substantially across trials, precluding pooling of
evidence.1,21 Two studies found no statistically … years after enrollment, 3 re-
ported statistically significant reductions in the average number of
USPSTF … visits, while 4 reported no group differences.1,21 Long-
term results (>4 years of follow-up) noted statistically … -
tistically nonsignificant) mortality rates in the intervention group
and 1 trial reported higher (statistically
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
August 20, 2024 - significant differences in rates of cesarean delivery (42.8% vs 41.5%; RR, 1.01 [95% CI, 0.90-1.14]; … significant differences in rates of maternal hemorrhage. 1 , 17
Infant Health Outcomes
Across 6 … significant differences in risk of preterm birth (5.5% vs 6.0%; RR, 0.92 [95% CI, 0.81-1.04]; I 2 … significant differences in infants with low birth weight (2.7% vs 2.9%; RR, 0.95 [95% CI, 0.79-1.14] … significant in adolescents (4.5% vs 12.6%; P = .320). 1 , 17 , 27 Infant harms were not reported
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening
December 10, 2019 - significant 35% reduction associated with invitation to screening (Peto OR, 0.65 [95% CI, 0.57-0.74] … The MASS and Viborg trials each found a statistically significant reduction in AAA-related mortality … significant benefit of screening for all-cause mortality at up to 15-year follow-up (HR, 0.97 [95% CI … , 0.95-0.99]). 1 Invitation to screening was associated with a statistically significant reduced rate … significant differences between the groups for up to 1 to 2 years.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
November 24, 2020 - Behavioral counseling interventions were associated with small, statistically significant reductions … All significance testing was 2-sided, and results were considered statistically significant at P < … While several characteristics showed statistically significant bivariate associations with the effect … The test of small-study effects was statistically significant for only the outcome of weight (Egger test … The association was still statistically significant in a sensitivity analysis excluding this study.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
January 19, 2021 - Although most studies were in the direction of benefit, no statistically significant increase in cessation … No statistically significant difference in rates of preterm births or stillbirths was found. … The 2 largest and most recent trials reported a statistically significant increase in smoking cessation … The 3 remaining trials reported no statistically significant differences in smoking cessation rates. … No statistically significant increase in headaches, dizziness, anxiety, or depression were found.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/HhFR4LyVtxMcwmafRH6Ehp
June 04, 2024 - Multifactorial interventions were associated with a
statistically significant reduction in falls (incidence … rate ratio [IRR], 0.84 [95% CI, 0.74-0.95])
but not a statistically significant reduction in individual … Exercise
interventions were associated with statistically significant reductions in falls (IRR, 0.85 … Exercise demonstrated the most consistent
statistically significant benefit across multiple fall-related … In contrast to the previous re-
view, there was no longer a statistically significant benefit of exer
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary22/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation-september-2015
March 30, 2015 - Twelve trials reported improvements in maternal hematologic indices, although not all were statistically … significant. … Pooled analysis of 4 trials resulted in a statistically significant difference in IDA incidence at term … Pooled analysis of 4 comparable trials (20 to 66 mg of iron daily) found a statistically significant … * P values in boldface show a significant difference.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary10/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
March 15, 2009 - Aspirin use in women was associated with statistically significant reductions in cardiovascular events … significant benefit was found in the reduction of myocardial infarctions or cardiovascular mortality … In men, aspirin use was associated with a statistically significant reduction in cardiovascular events … significant benefit was found in the reduction of ischemic strokes or cardiovascular mortality. … Increases in hemorrhagic strokes were not statistically significant in the aspirin group (RR, 1.24 [CI
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary32/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening-2013
May 08, 2012 - Two trials indicated no statistically significant differences between intervention and control groups … No statistically significant differences in sexual violence, verbal abuse, or injury between groups. … Total stress scores decreased in both groups with no statistically significant differences between groups … Community resource use declined for both groups ( P < 0.001) with no statistically significant differences … Other differences were not statistically significant (depression, physical well-being, mental well-being
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/drug-use-illicit-primary-care-interventions-for-children-and-adolescents-march-2014
March 11, 2014 - Drug use is associated with many negative health, social, and economic consequences and is a significant … The study did find a statistically significant reduction in the number of adolescents who did not initiate … The study's parallel group in the Czech Republic found a large and statistically significant reduction … They found statistically significant decreases in marijuana use and nonmedical use of prescription drugs … in all 3 studies after 12 to 24 months, as well as statistically significant decreases in inhalant use
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/c-7ARQE9RuXKjjpeLABkaH
March 01, 2007 - only
the highest dose of aspirin (for example, 300 mg and 325
mg per day) in each study resulted in a statistically … found that moderate and
high calculated cumulative dosing (�320 mg) of “any
NSAID” was associated with statistically … Health Study as-
sessed the efficacy of low-dose aspirin in decreasing colo-
rectal adenomas and found a statistically … those of NSAIDs or placebo in individuals
with active osteoarthritis or rheumatoid arthritis found a
statistically … significant higher rate of clinically significant
renal events for valdecoxib and NSAIDs (2% to 3%)
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-february-2005
February 15, 2005 - This trial lacked adequate power and reported a non-statistically significant 41 percent reduction in … A fair-quality hospital-based RCT of 12,658 men aged 65 to 73 showed a 69 percent statistically significant … In a subgroup analysis, there was a statistically significant reduction in AAA-related mortality in men … Two randomized trials showed no statistically significant mortality benefit from immediate surgical repair … A single normal ultrasonographic scan at age 65 years rules out significant aneurysm disease for life