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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6L2obA88s86MoZDbWtMPTU
December 01, 2011 - concentration was associated with a 6%
(95% CI, 3% to 9%) reduced risk for colorectal cancer but no
statistically … significant dose–response relationships for prostate
and breast cancer. … We tested for heterogeneity with the Coch-
ran Q statistic (considered significant when the P value was … This 3-group RCT enrolled a total of 1179 postmenopausal women.
‡ Statistically significant (P � 0.05 … All P values were
2-tailed, and a P value less than 0.05 was considered to
indicate a significant difference
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary43/prostate-cancer-screening-2012
October 07, 2011 - The other found no statistically significant effect after 10 years (relative risk, 1.1 [CI, 0.80 to 1.5 … significant difference in prostate cancer–specific mortality (RR, 0.85 [CI, 0.73 to 1.0]). … significant effect of screening on prostate cancer–specific mortality (RR, 0.84 [CI, 0.70 to 1.01]), … Screening based on PSA identifies additional cases of prostate cancer, but most trials found no statistically … significant effect on prostate cancer–specific mortality.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation-september-2015
September 07, 2015 - Most reported no statistically significant increase in harms. … Only 4 studies reported on infant mortality, 12 , 13 , 17 , 20 and none reported a significant difference … studies 15 , 20 , 21 , 22 reporting on small-for-gestational-age infants, 1 study 22 reported no significant … In general, no significant difference was found between supplemented and control groups.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-pregnant-women1/human-immunodeficiency-virus-hiv-infection-screening
June 11, 2019 - increased risk of very preterm (before 34 weeks) delivery (6.0% vs 2.6%, P = 0.04), but there was no significant … treatment with a protease inhibitor associated with a decreased risk of preterm delivery 19 or no significant … cardiovascular findings. 23 , 35 , 41 AUS cohort study of HIV-uninfected children (n = 2580) found no statistically … significant association between in utero exposure to currently recommended ART drugs and increased risk … There was no significant difference in echocardiographic parameters in boys, but in girls combination
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
December 24, 2013 - A woman's risk for breast cancer increases to 45% to 65% by age 70 years if there are clinically significant … In 1 study of 90 women who had risk-reducing bilateral mastectomy 73 , 74 , there were significant reductions … in scores for anxiety and sexual pleasure and no significant differences in depression scores, body … In another study 75 , there were no significant differences in psychological measures between women who … After risk-reducing salpingo-oophorectomy, premenopausal women reported significant worsening of vasomotor
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/syphilis-infection-in-pregnancy-screening
May 13, 2025 - Congenital syphilis is associated with premature birth, low birth weight, stillbirth, neonatal death, and significant … Congenital syphilis is associated with premature birth, low birth weight, stillbirth, neonatal death, and significant … statement include Task Force members serving at the time of publication and former members who made significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/UA7cEG8wH4xh8-fr7Lfw9q
September 18, 2018 - that intensive, multicomponent behavioral
interventions in adults with obesity can lead to clinically significant … There
were no significant differences in mortality between intervention
and control groups (4 trials … that examined health-
related quality of life (17 trials [n = 7120]) mostly demonstrated a
lack of statistically … significant differences between intervention and
control groups. … Pooling the trials (9 studies;
n = 3140) showed a significant reduction in the risk of developing
type
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary52/vitamin-d-and-calcium-to-prevent-fractures-preventive-medication-2013
December 10, 2011 - concentration was associated with a 6% (95% CI, 3% to 9%) reduced risk for colorectal cancer but no statistically … significant dose-response relationships for prostate and breast cancer. … We tested for heterogeneity with the Cochran Q statistic (considered significant when the P value … All P values were 2-tailed, and a P value less than 0.05 was considered to indicate a significant … ‡ Statistically significant (P < 0.05).
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Table 2.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary25/screening-for-abnormal-blood-glucose-and-type-2-diabetes-october-2015
April 13, 2015 - Figure 7 ). 45 , 48 , 52 Statistical heterogeneity was substantial, and the estimate was no longer statistically … significant using the profile likelihood method (RR, 0.51 [CI, 0.23 to 1.06]). … screen-detected diabetes aimed at decreasing glucose and lipid levels and BP was not associated with a statistically … significant reduction in risk for all-cause or cardiovascular mortality or morbidity versus standard … of the treatment phase of the ADDITION trial is needed to determine whether beneficial trends become statistically
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZYao53-sqRb6oZzKzDmjjt
December 01, 2003 - Obesity is an increasingly significant U.S. health
problem. … * Statistically significant (P < 0.05) but with insufficient data to calculate 95% confidence intervals … * Statistically significant (P < 0.05) but with insufficient data to calculate 95% confidence intervals … In a
sixth, not statistically significant trial, orlistat-treated
participants lost 5.8 kg more than … Intensive counseling programs require
significant time and staffing commitment.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-adults-screening-and-counseling-2003
December 15, 2003 - In a sixth, not statistically significant trial, orlistat-treated participants lost 5.8 kg more than … Obese patients can achieve modest but clinically significant, sustained (1-2 years) weight loss (e.g. … Intensive counseling programs require significant time and staffing commitment. … * Statistically significant (P < 0.05) but with insufficient data to calculate 95% confidence intervals … * Statistically significant (P < 0.05) but with insufficient data to calculate 95% confidence intervals
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6cRgd5whkAvSGESSQsrQLR
January 01, 2020 - among adults in the United States, accounting
for 1 in 3 deaths each year.1 Although CVD remains a significant … Noninvasive Imaging Research (EISNER) study, an
RCT of CAC score use in an academic setting, found no statistically … significant increase in downstream cardiac testing and procedures.29
In contrast, a retrospective study
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/fbQmoAPKeBekmJ7aqmALe5
June 01, 2014 - signifying
greater cognitive impairment; a change of 4 points or more
is commonly accepted to be clinically significant … Longer-term studies were generally con-
sistent with studies of shorter duration and demonstrated
statistically … significant small improvements of unknown
clinical importance.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002
January 01, 2002 - Summary estimates showed no significant effects of aspirin on total mortality (OR, 0.93; 95 percent CI
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/physical-activity-behavioral-counseling-primary-care-2002
July 01, 2002 - It was thus difficult to determine whether a specific counseling component was significant or essential … The study did not find any significant overall group differences in self-reported physical activity or … problems (chest pain, difficulty breathing, dizziness or loss of consciousness) over 2 years, with no significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/aHpXYasjc3n6zhaTtoWMwK
August 01, 2016 - One RCT reported a statistically significant reduction in viral
shedding outcomes, and the other did … The authors report that the treatment effect
was significant (P = .033, controlling for the crossover … effect); how-
ever, the arithmetic mean of the difference between groups was not
significant (11% [95% … At follow-up (median, 18 months), the number of susceptible part-
ners with seroconversions was not statistically … compared
with placebo for reducing viral shedding and symptom oc-
currences,26 and the other found no statistically
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZcuLSXJZXLz9Y2LECTWqVJ
November 01, 2009 - The studies are too
heterogeneous to combine statistically. … Despite a significant
increase in the number of cases of breast cancer detected
when BSE instruction … Trials of mammography screening for women aged 39
to 49 years indicate a statistically significant 15% … However, its results,
although consistent with the meta-analysis in the direction
of benefit, are not statistically … significant.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-1996
January 01, 1996 - screening in the general population may be made on other grounds, such as the low prevalence of clinically significant … available in any population, clinicians may decide to screen selected high-risk patients, due to the significant
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-1996
January 01, 1996 - disease and its treatment — surgical resection, colostomies, chemotherapy, and radiotherapy — can produce significant … over 840,000 patient-years of follow-up, a family history of colorectal cancer was associated with a significant … persons with colonic polyps discovered on routine sigmoidoscopic examination will not develop clinically significant … colonoscopy), procedures that are costly, anxiety provoking, and potentially harmful, are unlikely to be of significant … economic implications associated with the widespread performance of FOBT and sigmoidoscopy are clearly significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/WN7F3WW6RQFDkHay87a3Dx
November 18, 2020 - Results of the other trials were impre-
cise, without any statistically significant differences between … years of follow-up (IRR, 1.12
[95% CI, 1.02-1.22]).9,24 With extended follow-up, the NLST found
no statistically … significant difference between groups for overall
lung cancer incidence; however, this study had some … short-term.24
Studies reported a wide range of screening-related incidental
findings that were deemed significant … inconsistent definitions of
what constitutes an incidental finding and which findings were clini-
cally significant