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www.uspreventiveservicestaskforce.org/home/getfilebytoken/WEqCV3NvnZAeLdC_pp6nVK
October 01, 2018 - All significance testing was 2-tailed; P < .05 was considered statis-
tically significant. … significant.95,96 Results were similar
in 2 studies of ombitasvir/paritaprevir/ritonavir/dasabuvir12 … significant (ad-
justed HR, 0.74 [95% CI, 0.43 to 1.28]).68
Adolescents
Three treatment studies of … significant (eTable 3 in the
Supplement).59,61,100 Treatment studies of DAA therapy in adoles-
cents … significant (2 trials; RR, 1.53 [95% CI, 0.88 to 2.68];
I2 = 29%).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZR66ep5ABbQCUQy7KTDETn
July 01, 2014 - uated achieving virologic remission with lamivudine ther-
apy in HBeAg-negative patients and found no significant … Harms of Screening and Treatment
Pooled estimates showed no statistically significant dif-
ference between … There were no statisti-
cally significant differences between entecavir and lamivu-
dine or tenofovir
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/k-btyK4W2-v9KnemTK8WDx
September 14, 2021 - review indicated an
association between screening and decreased risk of PID, although
results were statistically … significant in only 1 trial.32 Chlamydia
screening was significantly associated with reduced risk for … ) or asymptomatic (65%)
young women in the UK, screening was not associated with a sta-
tistically significant … that screening for
chlamydia was associated with decreased risk of PID, although ef-
fects were not statistically … significant in most trials and the magni-
tude of benefit was relatively small.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/unhealthy-alcohol-use-in-adolescents-and-adults-screening-and-behavioral-counseling-interventions
November 13, 2018 - several trials in younger adults found that beneficial effects appeared at 6 months but were no longer statistically … significant at 12 months, suggesting that beneficial effects may deteriorate more quickly in younger … In addition, reported outcomes were generally not statistically significant and inconsistently favored … the intervention group. 1 In adults, 8 trials reported a statistically nonsignificant reduction in … addiction
Alcohol use disorder
DSM-5
A maladaptive pattern of alcohol use leading to clinically significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/CVoJ9fc9nv2Zsgs8R8XabH
September 01, 2022 - stage of infection,
syphilis can cause a variety of symptoms and, if left untreated, can lead to significant … The 2019 CDC sexually transmitted disease surveillance report highlights
significant disparities in … report
loss to followup data (i.e., retention of participants during the study period) and did not
statistically … 6 months in the other) was
associated with earlier detection of syphilis and identification of a significant … • Were key potential confounding variables measured and adjusted
statistically for their impact on
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6Ngc3byQ9jeBy_pwyvD6or
September 01, 2014 - For
all-cause mortality, we found no significant difference. … Subgroup analyses of the ACAS showed a statistically sig-
nificant reduction for men (relative risk reduction … In the ACST, reduction in the rate of first non-
perioperative strokes was statistically significant … potential for benefit, but subgroup analyses from
trials that compared CEA with medical therapy found no
significant … York state hospital discharges suggests that
carotid stenting in symptomatic women is associated with significant
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-and-ovarian-cancer-brca-testing-screening-2005
September 15, 2005 - Background: Clinically significant … decreases in generalized anxiety, although the reduction in psychological distress was not significant …
NA
* DVT = deep venous thrombosis; ER = estrogen receptor; NA = not available; NS = not statistically … significant; PE = pulmonary embolism; VTE = venous thromboembolic event.
** Calculated. … *Indicates clinically significant mutation of BRCA1 or BRCA2 .
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening-behavioral-counseling-1996
January 01, 1996 - years, 9 MM ranks second among adult-onset cancers in years of potential life lost per death. 10 Significant … providers in Scotland found a trend toward a reduction in both thick tumors (p < 0.05) and mortality (not statistically
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TuWmfBsDp6S9NXjTHNdGou
April 01, 2004 - familiar with
fluoride varnish.12 Four of 6 trials, including 3
randomized controlled trials, found statistically … significant reductions in the number of tooth
surfaces with cavitated lesions in children younger
than
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication-november-2016
November 13, 2016 - Compared with our original report, the pooled estimate for cardiovascular mortality was still statistically … significant though attenuated (risk ratio [RR], 0.82 [95% CI, 0.71-0.94]; I 2 =0% instead of RR, 0.69 … similar to those from recent systematic reviews, 46-48 although in 1 review the difference was not statistically … significant (RR, 0.91 [95% CI, 0.83 to 1.01]). 46
Outcomes associated with statin use appeared to … y
At risk for CAD
TC >251 mg/dL
LDL-C >155 mg/dL with ≥1 value 173-232 mg/dL
No significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/wyAJqjxBX_dHMF3WdA7WNt
September 05, 2017 - accuracy of screening for a broader range of vision con
ditions than most other studies, including significant … = 6019) assessed
the accuracy of Lea Symbols for identifying amblyopia risk factors or
clinically significant … Negative LRs were in the minimal range for detecting amblyopia risk
factors or significant nonamblyogenic … Preventive Services Task Force USPSTF Recommendation: Vision Screening in Children
screening and found no statistically … significant difference in the
prevalence of amblyopia at age 7.5 years for 3 definitions of
amblyopia
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/cardiovascular-disease-screening-using-nontraditional-risk-assessment
July 10, 2018 - among adults in the United States, accounting for 1 in 3 deaths each year. 1 Although CVD remains a significant … Noninvasive Imaging Research (EISNER) study, an RCT of CAC score use in an academic setting, found no statistically … significant increase in downstream cardiac testing and procedures. 29 In contrast, a retrospective
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hypertension-in-adults-screening
April 27, 2021 - All significance testing was 2-sided, and results were considered statistically significant if the P … There were no statistically significant differences in all-cause mortality among admitted residents (
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary34/lipid-disorders-in-children-screening-2007
July 15, 2007 - interest in screening children for dyslipidemia. 13-15
Dyslipidemia is defined by laboratory testing and statistically … b ↑ = significant increase.
c 0 = no significant change. … b ↑ = significant increase.
c 0 = no significant change. … No significant effects on ALT, AST, and CK. … Sitosterol: slight, significant decrease in hemoglobin
(-5%) and ALP (-19%).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Jwn6dWRHvK3C9oJCV6hLKc
September 05, 2017 - approximately 1% lower in
the intensive screening group than in the control group, but the dif
ference was statistically … likely in the 1-time screening group than in the
intensive-screening group, but the difference was statistically … participants who attended the examination at
age 7.5 years and were not part of the ALSPAC RCT, no statistically … The trial comparing patching plus eyeglasses, eyeglasses alone,
and no treatment found no statistically … They found no significant differences
between treatment groups with regard to being happy, coopera
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary43/prostate-cancer-screening-2012
October 07, 2011 - The other found no statistically significant effect after 10 years (relative risk, 1.1 [CI, 0.80 to 1.5 … significant difference in prostate cancer–specific mortality (RR, 0.85 [CI, 0.73 to 1.0]). … significant effect of screening on prostate cancer–specific mortality (RR, 0.84 [CI, 0.70 to 1.01]), … Screening based on PSA identifies additional cases of prostate cancer, but most trials found no statistically … significant effect on prostate cancer–specific mortality.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-2005
July 12, 2005 - elevated blood lipids, increased blood pressure, and impaired glucose tolerance. 24-29 Perhaps the most significant … non-Hispanic black, females aged 11 to 15 years with at least one obese biological parent resulted in statistically … significant differences in weight and BMI.108 Although both trials showed small but statistically significant … Among all trial completers (63-76% of all participants) at 12 months, significant improvements from baseline … Survey). 95 , 110 Differences between boys (no effect) and girls (elevated total scores) were not significant
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation-september-2015
September 07, 2015 - Most reported no statistically significant increase in harms. … Only 4 studies reported on infant mortality, 12 , 13 , 17 , 20 and none reported a significant difference … studies 15 , 20 , 21 , 22 reporting on small-for-gestational-age infants, 1 study 22 reported no significant … In general, no significant difference was found between supplemented and control groups.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/cognitive-impairment-in-older-adults-screening
February 25, 2020 - (Fifth Edition) ( DSM-5 ), dementia (also known as major neurocognitive disorder) is defined by a significant … Of the 12 trials that reported caregiver burden outcomes, 5 found a statistically significant improvement
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening-1996
January 01, 1996 - A significant difference in prevalence in the two populations has not, however, been demonstrated. … prostate cancer, however, suggesting that only a subset of cancers in the population are clinically significant … Cancer-related morbidity was significant, however. … generally safe but results in infection in 0.3-5% of patients, septicemia in 0.6% of patients, and significant