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www.uspreventiveservicestaskforce.org/home/getfilebytoken/y6xRBv7uSZY5bGCx7y48x7
May 01, 2009 - was provided by 3 fair-
or good-quality cohort, case–control, and meta-analytic
studies that found statistically … significant benefit; a small,
fair-quality case–control study reported benefit that was
not statistically … significant. … Although this difference was statistically
significant after adjustment for birth order, chronic ma- … These findings were not statistically significant when
the data were reanalyzed and twin deliveries were
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DMDPeSf_nEUM-HrVrX6c7U
June 20, 2017 - risk factors.3,4 A German expert panel determined that a BMI
z score reduction of 0.20 is clinically significant … statistically significant benefits of treatment. … Although the effects in the
less intensive trials were seldom statistically significant, interven
tion … significant.3
Pooled results did not demonstrate statistically significant
improvements in lipid … Trial results mostly demonstrated
small, statistically insignificant increases in quality-of-life scores
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nonpregnant-adolescents-and-adults1/human-immunodeficiency-virus-hiv-infection-screening
June 11, 2019 - Associations with all-cause mortality and AIDS-related mortality favored immediate ART but were not statistically … significant ( Table 1 ). … 1.02]), all-cause mortality, and AIDS-related mortality favored early ART ( Table 1 ) but were not statistically … significant. … composite outcome (death, AIDS events, and non-AIDS events) favored early ART, but the effect was not statistically
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary35/lung-cancer-screening-2004
May 15, 2004 - 1,000 person-years in the dual-screening group and 3.8/1,000 person-years in the control group (not statistically … significant differences) and were similar to community lung cancer mortality rates at the time. 71 , … significant findings. … 98 Although the higher lung cancer mortality rate among the intervention group in the MLP was not statistically … a Between-group differences were not statistically significant for all studies.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary21/depression-in-children-and-adolescents-screening-2009
March 15, 2009 - When considering individual SSRIs, fluoxetine and citalopram both yielded statistically significant higher … These results were statistically significant for both groups. … When data are pooled for individual drugs, they have not yielded statistically significant increases … That lack of statistically significant effects, however, may be a result of lack of power. … This result, however, was not statistically significant.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/carotid-artery-stenosis-screening
February 02, 2021 - Optimal treatment for clinically significant asymptomatic carotid artery stenosis remains uncertain. … The SPACE-2 trial 5 (n = 316) reported no significant difference in composite outcome of stroke or death … The smaller AMTEC trial 6 (n = 55) reported a statistically significantly lower composite risk of nonfatal
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary14/lung-cancer-screening
March 09, 2021 - Results of the other trials were very imprecise and did not show statistically significant differences … The other trials found no statistically significant differences between groups, but results were imprecise … smoking status (RR, 0.81 for current smokers vs 0.91 for former smokers; P = .40), and did not identify statistically … reported similar results for subgroups and did not identify statistically significant interactions by … Both LUSI and NELSON reported a similar pattern for subgroups by sex as found in the NLST that was not statistically
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/75ftPGW4rZ-3tdMQPstvDg
August 01, 2012 - 6 studies of multifactorial clinical assess-
ment with comprehensive management resulted in a non-
statistically … significant reduced risk for falling after 12
months compared with usual care (pooled relative risk … significant reduction
in risk for falling. … significant reduction in risk for
falling (pooled RR, 0.87 [CI, 0.81 to 0.94]) (1, 2). … significant results.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-depression-suicide-risk-adults
June 20, 2023 - The effect was smaller but still statistically significant when limited to studies in primary care patients … significant reductions in depressive symptom severity in the short term (typically 8 weeks). 1 , 58 … significant group differences in suicidal ideation at 2 weeks’ follow-up, with 1 suicide attempt among … significant (OR, 0.94 [95% CI, 0.73-1.22]; 12 RCTs [n = 14,573]; I 2 = 11.2%). 1 , 58 Pooled analyses … significant. 1 , 58
Two RCTs of suicide prevention treatment reported on harms.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/dementia-older-adults-screening-2003
June 03, 2003 - Most of these studies found a statistically significant difference favoring cholinesterase inhibitors … effect of cholinesterase inhibitors on functional decline after 6 months of treatment, and a small, but statistically … significant, difference from placebo after 12 months of treatment.[[29‐33]]
Ginkgo biloba, selegeline … examined interventions directed at caregivers of people with mild to moderate dementia and found no significant … Tacrine also has significant gastrointestinal and hepatic adverse effects.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Pboxx4DR35wz5GPozm-XNF
June 15, 2023 - significant differences in interval cancers
(pooled relative risk, 0.87 [95% CI, 0.64-1.17]; 3 studies … significant for DBT vs digital mammography in the individual trials. … Meta-analysis of 3 large
trials did not show a statistically significant difference in rates of in-
terval … significant compared with digital mammography only
after additional rounds of screening (Table 2).44 … This result differs from the statistically significant population-
average effect reported in the study
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/anxiety-adults-screening
June 20, 2023 - Significance testing was 2-sided, and results were considered statistically significant if P ≤.05. … Psychological interventions showed a relatively small but statistically significant reduction in anxiety … However, the effect was smaller and not statistically significant among mixed populations of people with … The overall pooled effect size for all 22 studies was statistically significant, in favor of the intervention … significant reduction in anxiety symptom severity in primary care patients with anxiety (SMD, −0.41
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
July 11, 2017 - There was evidence of small, statistically significant between-group mean differences for systolic blood … All significance testing was 2-sided, and results were considered statistically significant at P < … Of these 4 trials, 2 found statistically significant group × time effects on self-reported minutes of … Small, statistically significant improvements in SBP (−1.26 mm Hg [95% CI, −1.77 to −0.76], 22 studies … Small, statistically significant association with behavioral interventions and physical activity in favor
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Z_-5hkLbGePQPAYFCHVEyf
October 01, 2013 - children and adolescents and examined inter-
ventions to promote smoking cessation, found a small but
statistically … significant benefit from the
medication (1). … 26 624 children and ado-
lescents and examined smoking initiation in baseline non-
smokers, showed a statistically … significant reduction in risk
in youth who received the intervention at 6- to 36-month
follow-up compared … However, no trials reported a statistically sig-
nificant difference between the groups (1).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pskqLZMFcHjhtEF75uG4AP
January 01, 2012 - Hip fractures in partic-
ular can result in significant morbidity and mortality. … A pooled anal-
ysis of 9 trials demonstrated a non–statistically significant
trend toward a reduction … fractures (odds ratio [OR], 0.35 [CI, 0.17 to
0.77]), and the effect on nonvertebral fractures was not
statistically … significant (OR, 0.73 [CI, 0.32 to 1.67]) (10). … A single primary prevention trial of parathyroid hormone
reported a non–statistically significant trend
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/yzXkWEQV3pn95yd_pmXZXk
December 15, 2020 - alternate therapies
(lamivudine and adefovir).11,19
Pooled analysis showed that antiviral therapy was statistically … CI, 0.29-
1.77]) or hepatocellular carcinoma (4 trials; RR, 0.60 [95% CI, 0.16-
2.33]) that were not statistically … significant. … risk of hepatocellular car-
cinoma or composite health outcomes, but several associations were
not statistically … No significant differences in risk of
serious adverse events or withdrawal due to adverse events were
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/MWRHULpw6y_5Uk_KXTyvp8
January 10, 2017 - significant increased risk of twinning. … significant and could have oc-
curred because of chance. … The study found no statistically significant differences in the report-
ing of most of these symptoms … significant association of folic acid
supplementation with asthma or wheezing in childhood. … The 1
statistically significant association with wheezing in childhood
was associated with exposure in
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/oral-health-adults-screening-preventive-interventions
November 07, 2023 - There were no statistically significant group differences in number of decayed teeth or filled teeth, … Studies often had significant methodological limitations (eg, high attrition, unclear randomization, … , application of fluoride varnish (sodium fluoride 22,600 ppm) every 3 months was associated with a statistically … new active dental caries or fillings, 0.7; P > .05), but at 2 and 3 years, group differences were statistically … significant (mean difference, 1.8; P < .001 and mean difference, 1.6; P < .001, respectively). 1
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary29/hepatitis-b-virus-infection-screening-nonpregnant-adolescents-adults-may-2014
May 27, 2014 - However, differences were not statistically significant. … significant. … significant. … significant. … In some studies, results were not statistically significant.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/jRaQn9Em-jtem94yBDoZZ3
November 01, 2012 - Subgroup analyses identified no significant differences be-
tween men and women. … Our meta-
analyses found no statistically significant reduction in all-
cause mortality for adults (rate … 146 d, and
420 vs. 664 d, respectively; all P � 0.05§
Low Insufficient Fewer hospital days but no statistically … significant difference (131 vs. 150 d;
P � not significant)§
Low
Emergency visits No statistically … significant by 48 months.