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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Njxn2r3qtWKdBf2_VhS2Aw
April 01, 2016 - We observed a margin-
ally statistically significant reduction in cancer incidence
only when we restricted … They did not report a statistically significant effect on
CRC mortality during the first 5 years after … randomiza-
tion (HR, 0.78 [CI, 0.39 to 1.56]), but they did find a
borderline statistically significant … DISCUSSION
On the basis of 10 CVD primary prevention trials,
we found no statistically significant reduction … significant reduction in cancer incidence af-
ter 4.2 to 8.2 years.
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/breast-cancer-screening
April 30, 2024 - Trials reporting on at least 2 consecutive rounds of screening have generally found no statistically … significant difference in breast cancer detection or in tumor characteristics (tumor size, histologic … diagnosed with a stage IIB or higher cancer and cancer with less favorable characteristics was not statistically … The trials found no statistically significant difference in detection at the second screening round ( … There were no statistically significant differences in tumor diameter, histologic grade, and node status
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/T-DyWdyD67ktDMJGDp3jpm
June 01, 2003 - Most of these studies found a statistically
significant difference favoring cholinesterase
inhibitors … effect of cholinesterase inhibitors on
functional decline after 6 months of treatment, and
a small, but statistically … significant, difference from
placebo after 12 months of treatment.29–33
Ginkgo biloba, selegeline, … examined interventions directed at caregivers of
people with mild to moderate dementia and found
no significant … Tacrine also
has significant gastrointestinal and hepatic adverse
effects.
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www.uspreventiveservicestaskforce.org/uspstf/document/treatment-evidence-summary/gestational-diabetes-mellitus-screening-january-2014
May 28, 2013 - † Statistically significant with better results for the treated group.
‡ Mean difference. … § This result was statistically significant; however, all untreated women in this cohort presented … † Results statistically significant with better results for the treated group. … Five randomized, controlled trials contributed data; pooled results showed no significant difference … The pooled results are reported in the text and showed no significant difference between groups (mean
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2DGd8AvVMTJwP3ttrPcnLL
February 25, 2020 - follow-up was
most commonly at 12 months but ranged from 7 to 36 months).14
This finding was not always statistically … significant for individual
studies; however, this reduction was statistically significant when
results … Meta-analysis of all 9 trials reported a risk
reduction of percent smokers after the intervention that was not
statistically … rates at follow-up in intervention groups com-
pared with control groups, but this finding was not statistically … significant in any of the trials.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-and-nicotine-use-prevention-in-children-and-adolescents-primary-care-interventions
April 28, 2020 - follow-up was most commonly at 12 months but ranged from 7 to 36 months). 14 This finding was not always statistically … significant for individual studies; however, this reduction was statistically significant when results … Meta-analysis of all 9 trials reported a risk reduction of percent smokers after the intervention that was not statistically … smoking rates at follow-up in intervention groups compared with control groups, but this finding was not statistically … significant in any of the trials.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-adults-screening-1996
January 01, 1996 - life-table analyses suggested a survival advantage for the untreated group, but the differences were not statistically … significant. … treatment, compared to 7.9% and 3.2%, respectively, with treatment, but these differences were not statistically … Further evaluation of the Griess test to detect significant bacteriuria. … Asymptomatic significant bacteriuria in the non-pregnant woman. II.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/JxCqP7cXvVRftQGUDJZdB-
December 01, 2014 - Incidence of
STIs decreased in all 8 comparisons, although results were
not statistically significant … This trial found a small but statistically
significant reduction in the proportion of participants with … Planned subgroup analyses revealed that
the effect was statistically significant for men (adjusted haz … However, 1 study of risk-reduction
counseling with rapid HIV testing showed a paradoxical,
statistically … significant increase in the incidence of STIs in
MSM (18.7% in men who received behavioral counseling
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/obesity-in-children-and-adolescents-screening
June 18, 2024 - Reporting was sparse for outcomes other than BMI, with few significant findings. … All significance testing was 2-sided, and results were considered statistically significant if P ≤ … Very few individual studies found any statistically significant improvements in quality of life at any … significant, most evidence and the meta-analyses indicated no effect on minutes per day of physical … This finding was statistically significant in the meta-analysis among the high-contact (but not the lower-contact
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening-october-2018
October 23, 2018 - The USPSTF recognizes that a significant body of evidence is lacking for men. … groups was small (standardized mean difference, −0.04 and −0.34, respectively), and only 1 study found a statistically … Two RCTs reported on depression, and both found benefit in favor of the intervention (only 1 found a statistically … in both trials, scores were similar between intervention and control groups and differences were not statistically … No study found significant harms associated with the interventions.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/5UgQm-zskVEKmcVnczHxGY
July 01, 2012 - Smaller albeit significant improvements were seen in com-
posite scores of sun-protective behaviors in … trial
(11) that provided counseling to parents of newborns in a
series of 4 well-child visits showed statistically … significant
improvement in composite sun-protection scores in the in-
tervention group. … However, most individual measures were
statistically insignificant, and overall it was difficult to de … Four of 5 observational stud-
ies showed no statistically significant association.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary29/obstructive-sleep-apnea-in-adults-screening
November 15, 2022 - mean baseline ESS score of less than 10, the effect size was smaller and the pooled estimate was not statistically … significant (eFigure 4 in the JAMA Supplement). … Three RCTs reported on the incidence of motor vehicle crashes over 12 to 52 weeks, and none found a statistically … Two studies reported that there was a statistically significant difference only in the percentage who … with known OSA
MADs
Blood pressure: 1 systematic review (11 RCTs; 469 participants)
No statistically
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening-2011
January 15, 2011 - Hip fractures in particular can result in significant morbidity and mortality. … A pooled analysis of 9 trials demonstrated a non-statistically significant trend toward a reduction in … fractures (odds ratio [OR], 0.35 [CI, 0.17 to 0.77]), and the effect on nonvertebral fractures was not statistically … significant (OR, 0.73 [CI, 0.32 to 1.67]) 10 . … A single primary prevention trial of parathyroid hormone reported a non-statistically significant trend
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/FaN-QvpDgnJh8KrdF4smmv
May 01, 2013 - No statistically significant
reduction in fractures was observed in these studies (pooled
relative risk … This study re-
ported no statistically significant reduction in hip fracture
(hazard ratio, 0.88 [CI, … thresholds were not predefined by
the original trial authors, and the reduction was not con-
sidered statistically … significant when adjusted for several
subgroup analyses.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ph_fauqHQjmrSqPAWKrARA
September 28, 2021 - No individual study reported a statistically significant
difference in perinatal mortality, but all were … underpowered for the
outcome; however, the pooled estimate showed a statistically sig-
nificant 21% … Aspirin was
associated with statistically significant reduction in the risk of pre-
eclampsia compared … There were no
statistically significant differences in the risk of abruption or post-
partum hemorrhage … studies enrolled significant numbers of other minority racial or
ethnic groups.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/cognitive-impairment-in-older-adults-screening
February 25, 2020 - All significance testing was 2-sided, and results were considered statistically significant if the P … Mixed-effects models showed no statistically significant differences between groups at any time point … significant benefit. … Psychoeducation interventions resulted in a small but statistically significant benefit on caregiver … significant benefit.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/_SBmXPhUQWo-dc85FJ5wHf
February 01, 2015 - significant (rate
ratio, 0.89 [CI, 0.79 to 0.99]; P = 0.03). … These results were statistically
significant in 5 studies (Figure 1) (34, 36, 38, 41, 43). … All
showed statistically significant associations with an in-
creased risk for cardiovascular and mortality … One good-
quality (72) and 3 fair-quality (73–75) trials found no
statistically significant differences … Among those
randomly assigned to screening, there was a small but
statistically significant reduction
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/impaired-visual-acuity-in-older-adults-screening-2016
March 01, 2016 - Results were considered statistically significant if the P value was less than 0.05 based on 2-sided … significant (adjusted OR, 0.75; 95% CI, 0.55–1.02). … visual acuity (RR, 2.92; 95% CI, 1.20–7.12; I 2 = 76%), but the absolute risk difference was not statistically … significant (10%; 95% CI, −7% to 27%). … significant (adjusted OR, 0.75; 95% CI, 0.55-1.02).
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
November 13, 2016 - Results were mixed, but most large trials found that statin use led to a statistically significant reduction … significant differences in the risk of experiencing any serious adverse event. … significant differences in performance scores on tests of attention, visual perception, motor and processing … significant differences between the intervention and control groups for myalgia (7 trials; pooled RR … significant increased risk of diabetes with statin use. 10 In post hoc stratified analysis, participants
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breastfeeding-primary-care-interventions
April 11, 2025 - All significance testing was 2-sided, and results were considered statistically significant if P < … However, very few reported these differences to be statistically significantly different between groups … In meta-analyses, there was a statistically significant association between participating in a breastfeeding … A meta-analysis of 8 trials (n = 4607) found no statistically significant association with receiving … significant
Nine trials (n = 2334) reported minimal differences between groups in maternal well-being