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www.uspreventiveservicestaskforce.org/home/getfilebytoken/bQNXFv9Q5uaAQvWH6B7VWV
June 11, 2019 - significant. … One
open-label trial (n = 544), which enrolled men who have sex with
men, found no statistically significant … events, there was no statistically significant in-
teraction between PrEP regimen and any adverse event … There was no statistically significant interaction between HIV
risk category and risk of STIs. … There was no statistically significant association
between PrEP and increased risk of fracture,12,14,17,18,27,33,42
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/RrE4_peSk5zVH3cCf77at3
June 24, 2025 - nents with other support services (eg, parenting support, referral
to community services); 1 found a statistically … significant reduction
Figure 3. … and fewer very preterm neo-
nates (�33 weeks) (2 vs 9 women; P = .03) than the control group,
but no statistically … ).38-40 Last, 1 RCT
enrolling new parents (n = 368 couples) with a history of verbal
abuse found no statistically … 2 to 3 y associated with the
intervention; however, the difference between groups
in 1 RCT was not statistically
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening-2012
May 15, 2012 - significant reduction. … significant lower risk of dying of prostate cancer than healthier men. 23 , 34 Preliminary results … subgroup analysis limited to men aged 55 to 69 years, a statistically significant reduction in prostate … significant reductions in prostate cancer deaths with PSA screening. … After a median follow-up of 10 years, prostate cancer–specific or all-cause mortality did not statistically
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/hepatitis-b-virus-infection-screening
December 15, 2020 - alternate therapies (lamivudine and adefovir). 11 , 19
Pooled analysis showed that antiviral therapy was statistically … CI, 0.29-1.77]) or hepatocellular carcinoma (4 trials; RR, 0.60 [95% CI, 0.16-2.33]) that were not statistically … significant. … lower risk of hepatocellular carcinoma or composite health outcomes, but several associations were not statistically … Pooled analyses found no significant differences in the risk of serious adverse events (4 trials; RR,
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
August 22, 2023 - significant ( P = .03), indicating potential publication bias (eFigure 2 in the JAMA Supplement). … Oral PrEP was associated with a modestly decreased risk of mortality that was not statistically significant … significant ( P = .09), 18 indicating no statistically significant difference in treatment effect … significant ( P = .13) and the estimate for event-driven PrEP was similar to daily dosing with high … There were no statistically significant interactions with age, race, ethnicity, geographical region,
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/cervical-cancer-screening-adults-adolescents
December 10, 2024 - Implementation
A significant amount of evidence shows that self-collection of primary HPV screening … One trial reported ICC detection after two rounds of screening and found a statistically significant … detects more CIN2+ and CIN3+ lesions in one round of screening compared with cytology; results were not statistically … significant for CIN3+ (pooled RR, 1.13 [95% CI, 0.98 to 1.30]) but were statistically significant for … In six studies, primary HPV screening was associated with a statistically significant increase in colposcopy
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary25/folic-acid-to-prevent-neural-tube-defects-preventive-medication-2009
May 15, 2009 - was provided by 3 fair- or good-quality cohort, case-control, and meta-analytic studies that found statistically … significant benefit; a small, fair-quality case–control study reported benefit that was not statistically … significant. … Although this difference was statistically significant after adjustment for birth order, chronic maternal … significant.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary39/obesity-in-children-and-adolescents-screening-2010
January 15, 2010 - significant ( Table 1 ; Figure 3 ). … significant, short-term benefit ( P = .006). … significant. … significant cross-sectionally, we show it as being statistically significant in Table 3 and in the text … considered statistically significant and used in the meta-analysis of short-term effects.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-june-2017
June 20, 2017 - factors. 3 , 4 A German expert panel determined that a BMI z score reduction of 0.20 is clinically significant … Only 3 of the 24 trials with less than 26 contact hours showed statistically significant benefits of … Although the effects in the less intensive trials were seldom statistically significant, intervention … significant. 3 Pooled results did not demonstrate statistically significant improvements in lipid or … Trial results mostly demonstrated small, statistically insignificant increases in quality-of-life scores
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2XRG8Dz2EegVWYUrRThgmD
October 01, 2015 - This study reported no statistically
significant differences in rates of total mortality, coro-
nary … significant. … ENDS 2 RCTs 1 trial found no statistically
significant difference in
biochemically verified
abstinence … At 6 months, this trial reported no statistically
significant differences in biochemically verified contin … significant result (RR, 0.41 [CI, 0.18 to
0.94]) (82).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/m_E9nFrmxuS5-surqVHK2u
November 13, 2018 - The associations re-
mained statistically significant when limited to trials conducted in
primary care … A pooled analysis showed a statistically significant, but
very small, standardized mean difference in … Differences in mortality between groups were
statistically significant at 3 years of follow-up, when … This trial also reported statistically significant reductions
in days of hospitalization (420 in the … a wide range of outcomes, even though differences were not al-
ways statistically significant, suggests
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary8/abdominal-aortic-aneurysm-screening-2014
January 15, 2014 - reduced AAA rupture and AAA-related mortality rates for up to 10 and 15 years, respectively, but had no statistically … significant effect on all-cause mortality rates up to 15 years. … The good-quality MASS and Viborg trials showed statistically significant reductions in AAA-related mortality … trials showed a tendency toward reductions in AAA-related mortality rates with screening that was not statistically … significant. 33 , 42
An invitation to AAA screening was not associated with a statistically significant
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nop5YpEpMybx_oNPKC76-X
July 11, 2017 - appeared to be a dose-response effect, with higher-intensity
interventions demonstrating greater and statistically … significant
benefits. … Few deaths occurred
in these trials, and no significant effect was seen in all-cause or CVD-
related … The results, however, were not statistically
significant when revascularization was removed from the … When all
good- and fair-quality intervention trials were pooled, they
demonstrated statistically significant
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary13/child-maltreatment-primary-care-interventions-2013
January 15, 2013 - Five trials reported no statistically significant effects of home visitation on the number or percentage … home-visited children received immunizations at an earlier age than control children, resulting in significant … A trial reporting significant differences in the mean number of well-child visits at 9 months (3.14 vs … One trial found a significant difference in self-reported severe physical assault at 36 months (4% of … Most of the statistically significant benefits of home visitation were demonstrated by trials with more
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-b-virus-infection-screening
December 15, 2020 - alternate therapies (lamivudine and adefovir). 11 , 19
Pooled analysis showed that antiviral therapy was statistically … CI, 0.29-1.77]) or hepatocellular carcinoma (4 trials; RR, 0.60 [95% CI, 0.16-2.33]) that were not statistically … significant. … lower risk of hepatocellular carcinoma or composite health outcomes, but several associations were not statistically … Pooled analyses found no significant differences in the risk of serious adverse events (4 trials; RR,
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002
January 15, 2002 - Of the five trials, only PHS reported a statistically significant decrease in risk with aspirin (OR, … There was no significant heterogeneity in trial results ( P > 0.2). … The results displayed no significant heterogeneity ( P > 0.2). … However, its effect in women was smaller and not statistically significant (1.7/1,000 patient-years in … significant.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/xUc_vXf7323faUQY7SePhT
January 01, 2002 - Of the 5 trials,
only PHS reported a statistically significant decrease
in risk with aspirin (OR, 0.64 … There was no
significant heterogeneity in trial results (P>0.2). … The results displayed no significant
heterogeneity (P>0.2). … However, its effect in women was smaller and not
statistically significant (1.7/1,000 patient-years … significant.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VN82XmdDhcK74WtHxWBTqm
May 01, 2004 - the intervention group was
0.7/1,000; the rate was 0.8/1,000 in the control
population, not different statistically … 1,000 person-years in
the dual-screening group and 3.8/1,000 person-years
in the control group (not statistically … significant
differences) and were similar to community lung
cancer mortality rates at the time.71,72 … significant for all studies … significant findings.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary14/chlamydial-infection-screening-2007
June 15, 2007 - There is a significant evidence gap regarding the ability of screening in men for chlamydial infection … Both of these differences were found to be statistically significant. … investigators noted a lower adjusted relative risk for hospitalization for PID, but this difference was not statistically … significant (0.94 [CI, 0.69 to 1.29]). … Has the epidemiology of chlamydial infection in the United States changed in significant ways since 2001
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/9H5mgkBCjNQVZZ4pnkNo6B
February 01, 2016 - In contrast, the combined
fluoxetine and CBT group of TADS found significant
differences in response … These differences were not statisti-
cally significant. … patients from
primary care or school
clinic settings
1: Good
3: Fair
The fluoxetine study found a
statistically … statistically significant benefits for
relapse; the citalopram trial did
not find significant differences … 983 Limited number of studies;
only escitalopram had more
than 1 trial; analyses not
powered to find statistically