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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 28, 2021 - All significance testing was 2-sided, and results were considered statistically significant if P < … No individual study reported a statistically significant difference in perinatal mortality, but all were … underpowered for the outcome; however, the pooled estimate showed a statistically significant 21% reduction … Aspirin was associated with statistically significant reduction in the risk of preeclampsia compared … There were no statistically significant differences in the risk of abruption or postpartum hemorrhage
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-use-in-children-and-adolescents-primary-care-interventions-2013
August 15, 2013 - children and adolescents and examined interventions to promote smoking cessation, found a small but statistically … medication (sustained-release bupropion alone or combined with nicotine replacement therapy) showed no statistically … significant benefit from the medication 1 . … significant reduction in risk in youth who received the intervention at 6- to 36-month follow-up compared … However, no trials reported a statistically significant difference between the groups. 1
Estimate of
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-d-and-calcium-to-prevent-fractures-preventive-medication-2013
February 15, 2013 - In the Women's Health Initiative (WHI), a statistically increased incidence of renal stones occurred … No statistically significant reduction in fractures was observed in these studies (pooled relative risk … This study reported no statistically significant reduction in hip fracture (hazard ratio, 0.88 [95% CI … thresholds were not predefined by the original trial authors, and the reduction was not considered statistically … significant when adjusted for several subgroup analyses.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/eSLqaKpvzhYRbQVeumNgSQ
January 19, 2021 - significant differences between interven-
tion and control groups in rates of total mortality (41.5% … significant differences
had larger samples and estimated effects closer to null, with RRs
ranging from … significant
NA Only 1 review reported the results of 1 intervention in
men; within that trial, the … significant effect
Inconsistent; imprecise Highly variable study designs and included interventions … significant higher likelihood of quitting smoking at 6 months compared with those
randomized to NRT
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/h-w99jVsodSL33kV2h2_qW
April 17, 2018 - significant. … Five trials (n = 3496) reported mixed findings.8 Only 1 trial
showed a statistically significant reduction … in falls8,18; however,
another study using high doses of vitamin D (500 000 IU per year)
showed a statistically … significant increase in falls.8,19 Pooled analy-
ses showed neither a significant reduction in falls … Pooled analy-
ses revealed statistically significant reductions in 1 fall-related out-
come (number of
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-in-children-and-adolescents-screening-2009
March 15, 2009 - reported as ranging from 9 percent to 21 percent in primary care settings. 1
MDD is associated with significant … Fluoxetine and citalopram yielded statistically significant higher response rates than did other SSRIs … Pooled data for individual drugs did not show statistically significant increases in suicide-related … This result, however, was not statistically significant.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/HQGXw2wkcM7q6TA5eWzdT5
January 01, 2010 - significant. … Two
fair-quality trials in young women attending primary care
clinics showed no statistically significant … significant
differences in STI incidence. … significant (21). … Pre–sexually active and sexually active adolescents: One trial did not show a statistically
significant
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/sexually-transmitted-infections-behavioral-counseling-september-2014
September 22, 2014 - Results were very similar, and all statistically significant results remained statistically significant … significant in 2 trials 10 , 15 . … significant. … We found no statistically significant paradoxical increase in the overall incidence of STIs among any … A subgroup analysis in 1 trial, however, showed a statistically significant deleterious effect on STI
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6fMLEz4CfAVoj9YBYVbm73
April 17, 2018 - Potential Harms
The WHI trial found a statistically significant increase in the inci-
dence of kidney … supplementation found find-
ings consistent with those from the WHI trial, although the in-
crease was not statistically … significant. … the effect of combined vi-
tamin D and calcium supplementation on risk for hip fractures and
found no statistically … to
1.08]).14 The WHI trial also did not find any statistically significant
difference in total fractures
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening-1996
January 01, 1996 - The prevalence of hemodynamically significant carotid stenosis varies with age and other risk factors … considerably smaller (estimated 5-year risk of 3.4% in the surgery group vs. 6% in the medical group), not statistically … significant (p = 0.13), and evident only in the fifth year of follow-up. … complication rates (3.6% in women vs. 1.7% in men) neither of these differences between genders was statistically … significant, however.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pKa4_DYwzuyD6RDgYzLMbo
August 22, 2018 - improve-
ment in some 36-Item Short Form Health Survey subdomains, no dif-
ference in others, and statistically … 0.29 to 0.80])31 and fewer very preterm neonates (�33
weeks) (2 vs 9 women; P = .03); there was no statistically … life; both found similar scores among the interven-
tion and control groups, and differences were not statistically … other home visit intervention
found an association with reduced IPV exposure, but
differences were not statistically … both groups with
no statistically significant differences and 2 reported
on subtypes of violence only
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/g-b8KbTXYe2vnW2zJKGoPU
April 01, 2015 - The only
study reporting statistically
significant differences in growth
parameters found lesser growth … 1657,
respectively), including the Chilean
study with methodologic flaws
mentioned earlier, found no
statistically … scores in children
with normal iron status at
baseline.22,25,30 Two fair-quality
studies (Table 3) found statistically … NS, not significant. … Prevention.2,37,38
In addition, 1 of the largest studies
included in the review that
consistently found statistically
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-97QgoUF_rpQSy-9yM9KCx
November 24, 2020 - Behavioral counseling interventions were associated with small, statistically significant
reductions … All significance testing was 2-sided, and results were consid-
ered statistically significant at P < … effect size showed a statistically significant association only for the
composite outcome of any CVD … While several characteristics showed statistically significant
bivariate associations with the effect … The association was still statistically
significant in a sensitivity analysis excluding this study.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/vision-in-children-ages-6-months-to-5-years-screening
September 05, 2017 - likely in the 1-time screening group than in the intensive-screening group, but the difference was statistically … participants who attended the examination at age 7.5 years and were not part of the ALSPAC RCT, no statistically … The trial comparing patching plus eyeglasses, eyeglasses alone, and no treatment found no statistically … d Although the difference was not statistically significant, the point estimates of the effect were … significant for 1 of 2 definitions of amblyopia. a
In cohort study, no statistically significant
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary9/alcohol-misuse-screening-and-behavioral-counseling-interventions-in-primary-care-2013
September 25, 2012 - Subgroup analyses identified no significant differences between men and women. … Our meta-analyses found no statistically significant reduction in all-cause mortality for adults (rate … significant by 48 months. … significant at 12 mo (low strength). … significant difference (131 vs. 150 d; P = NS) §
Low
Emergency visits
No statistically significant
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/skin-cancer-counseling
March 20, 2018 - the effect of interventions on sun protection behaviors among children and adolescents, 5 reported a statistically … Among the 4 trials in children aged 3 to 10 years, 3 showed statistically significant differences in … trial 13 that provided counseling to parents of newborns in a series of 4 well-child visits showed statistically … significant improvement in composite sun protection scores in the intervention group. … However, most individual measures were not statistically significant, and it was difficult to determine
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/oo3XPmknWkhsBbAuYZQyQw
November 24, 2020 - significant for either outcome. … The pooled effect did not
demonstrate a statistically significant benefit (pooled RR, 0.89
[95% CI, 0.71 … Overall, inter-
ventions involving counseling on diet and physical activity led to
statistically significant … Overall, behavioral counseling resulted in
small, statistically significant improvements in saturated … The
pooled effect of continuous outcomes was not statistically signifi-
cant (pooled standardized mean
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4_pXjq7Egjwb_vjZZT-NGB
May 01, 2021 - The studies did not
report statistically significant differences in maternal and infant complications … The study examined several serious ma-
ternal and infant health outcomes; none were statistically significant … in days to detection of hypertensive disorder
of pregnancy, was less than 2 days (SD, 1.6) and not statistically … significant (RR, 0.79 [95% CI, 0.40-1.55])
Estimated risk of SGA/IUGR was not statistically
significant … )
Slightly higher incidence of severe hypertension in
home measurement group (6.0% vs 4.8%) but not
statistically
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vmHooQ6ABG9CagdUXv2_rx
August 25, 2021 - proprotein convertase subtilisin/kexin type 9 inhibitor,
and statin plus ezetimibe combination drugs showed statistically … Two
trials of omega-3 fatty acids did not show a statistically significant
difference in lipid level … ) with dietary interventions varying in inten-
sity, duration, and follow-up showed a 3- to 6-mg/dL statistically … There were no significant differences
in Tanner staging or hormonal adverse events between statin and … This increased risk, however, dissi-
pated and became statistically nonsignificant when a combined risk
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/depression-in-children-and-adolescents-screening
February 08, 2016 - These differences were not statistically significant. … The good-quality collaborative care trial 20 found no significant differences in the mean number of … patients from primary care or school clinic settings
1: Good
3: Fair
The fluoxetine study found a statistically … statistically significant benefits for relapse; the citalopram trial did not find significant differences … Limited number of studies; only escitalopram had more than 1 trial; analyses not powered to find statistically