-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
January 01, 2010 - Pittet and colleagues demonstrated a significant reduction in MRSA
bloodstream infections in one especially … Jernigan and colleagues noted a significant
decrease in the risk of MRSA transmission when isolation … Only the addition of active
surveillance resulted in a statistically significant decline in the incidence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
July 26, 2012 - There is clearly a significant need for more Level
One investigations in this field. … CI, 0.39 to 2.80]) to clarify that the
difference in risk of symptomatic stone
recurrence was not statistically … significant. … There is clearly a significant need for more Level
One investigations in this field. … By counting only symptomatic episodes as
“recurrences”, a significant number of episodes of true stone
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_disposition-comments.pdf
October 27, 2015 - The latter is an area of significant clinical
need and confusion with regard to best
treatment. … There are
significant limitations to any analysis that
can be performed especially with markers. … This is considered an area of significant
need but is not addressed. … SWOG 8507 clearly shows
a highly statistically significant benefit to 3
yr. maintenance vs. induction … FISH, but
the table shows a significant difference in
specificity between the two (p=0.0001).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
June 22, 2017 - The authors
correctly point out that post-phlebitic
syndrome can be a significant clinical
problem … Venogram only
DVT did not rank as significant
Symptomatic DVT was an outcome of
interest included … Using
statistical techniques we did not find
significant evidence of bias (significant
differences … Peer
Reviewer #4
Results Results for network MA
For the many significant comparisons, do
the FE … model provide a role to make is
easier to see significant comparisons?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - number of adolescents and young adults currently affected by an ASD, as
well as a significant cohort … ASDs are characterized by significant impairments in
social interaction, behavior, and communication … While we acknowledge that ASD undoubtedly has significant effects on family
functioning, exploring the … They are
also frequently adapted to be targeted to specific study participants given the significant … In contrast to Autistic
Disorder, there are no clinically significant delays or deviance in language
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
November 18, 2024 - long-chain PUFA
o Intake of PUFA
in terms of a ratio
• Diet(s) with an energy intake that is
statistically … than
the intervention/exposure diet (e.g., not
isocaloric comparison)
• Studies that do not have a statistically … significant difference between groups in
PUFA or total fat intake
• Studies comparing undefined … We will classify the magnitude of effects for measures
(e.g., ≤ SS = 85 as clinically significant, ≤ … T-score = 40 as clinically significant for behavioral
measures).
-
effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
January 01, 2012 - In the post-treatment period, significant reductions in depression and HIV RNA were
observed, while … significant increases in CD4 T-cell count and antidepressant prescriptions
were observed compared … Key Expert Comments: Overall, experts stated a significant unmet need exists for earlier
anal … Experts thought that emtricitabine/tenofovir could have a
significant impact on health promotion by … All but one
item sampled had a statistically significant reduction in microbial burden.
107
Clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
January 27, 2016 - I did notice
inconsistency regarding including whether
results were statistically significant (see … visit (0.5%; 6/1101) compared
with the usual care group (0.2%;
2/861), but the difference was not
statistically … significant…”
Instead of stating that there was a difference
but not statistically significant, the … is very
wide such that we cannot
conclude that there is no
difference, but must
conclude that a statistically … significant difference was not
found.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - But the surgery has significant associated risks and mortality; and
the drug therapy has undesired … The
committee stated “the lack of obesity medications is a significant unmet medical need.” … discontinuation rate, which they believe to be significant adverse factors. … phase 3 trials show obese and
overweight patients taking Arena Pharmaceuticals'
Lorcaserin achieved statistically … significant weight
loss.
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
February 24, 2016 - Executive Summary Key Question 3b, Page 23/Perioperative
Outcomes
Page 140 I have a significant issue … Therefore, the clinically significant implications of nephron-
sparing management strategies are not … We changed the language to state: “but is
associated with a significant non-diagnostic rate.” … Any specific instances of
individual studies that diverged from this finding
(and perhaps state a statistically … significant
association, regardless of the magnitude of
difference) are discussed in the main text
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
November 27, 2012 - cirrhosis, liver cancer
and liver failure often take decades to present, it is
anticipated that a significant … Summary
(ES-12)
Row 1: "…slightly better short-term scores…" Please
state whether the difference is statistically … significant,
and, if so, please state the magnitude of the
difference and the p-value. … We revised this to indicate that differences were statistically
significant. … factors for
infection and emphasize the importance of parenteral
drug abuse and the high prevalence of significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
July 08, 2014 - Neither showed statistically significant
differences between groups, although the study size makes … identifying significant differences difficult. … pregnant women
who did not receive an SSRI (depression status unknown) found the
risk for ASD was statistically … CI 1.50 to 7.47),
while the risk in women taking an SSRI for another indication was
lower and not statistically … significant (OR 1.61; 95% CI 0.85 to 3.06).”
-
effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
March 01, 2011 - Studies rated “poor” have significant flaws
that imply biases of various types that may invalidate … as
well as slightly more ICA referrals (13% vs. 8%; RD,
5; 95% CI, -4 to 14 per 100 people; p not statistically … Through 6 months,
ICA referral was statistically less frequent in the stress
echocardiography group … For the latter study,
although the differences between groups were statistically
significant for both … comparators, they may not be
clinically significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/child-growth-development-outcomes-protocol.pdf
August 19, 2024 - • Dietary intake of a
different amount of
total fat
• Diet(s) with an energy intake that is
statistically … than
the intervention/exposure diet (e.g., not
isocaloric comparison)
• Studies that do not have a statistically … significant difference between groups in
PUFA or total fat intake
• Studies comparing undefined … We will classify the magnitude of effects for
measures (e.g., ≤ SS = 85 as clinically significant, ≤ … T-score = 40 as clinically significant for
behavioral measures).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - The study reported no
statistically differences for depression, anxiety, bipolar disorder or psychotic … no differences in first-time psychiatric episodes treated at
outpatient facilities but did find a significant … The authors suggest that
childbirth could serve as a “potent and highly significant trigger” of severe … high-dimensional propensity scores have found that full
adjustment leads to many associations being no longer statistically … significant.38, 39
The heterogeneity of included populations and pharmacologic interventions adds
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
January 01, 2015 - All treatment-by-
MDD interactions for pain were either not significant or
not reported. … The interaction result was not reported; the
text implies that it was not significant.3
Treatment-by-MDD … Impression
of Improvement (PGI-I).76 For the PGI-I outcome, the
duloxetine-by-MDD interaction was not statistically … The interaction term was not
significant. … (p >0.1),20 but the treatment-by-
MDD stratum interaction was significant for “treatment-
emergent”
-
effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
October 01, 2007 - The
advent of Medicare Part D for outpatient prescription drugs has
drawn significant attention to the … ie, outpatient rather than inpatient).14
Methods to Control Confounding and Reduce
Bias
Among the significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - additives to
dressings, such as shale oil, tenuiflora bark, and human
keratinocyte lysate, found no statistically … significant
difference. … One of the studies demonstrated a statistically
significant improvement in ulcer healing as measured … percent) than with
trimethoprim (33 percent) or placebo (30 percent), but the
differences were not statistically … significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Preliminary data suggest that in some patients, low-
dose ketamine produces significant, rapid (within … Experts thought that SPARX could positively improve patient health outcomes without
placing significant … Some experts concluded that this
cost would not be a significant burden to patients with reduced financial … adolescents who
completed SPARX had larger mean CDRS score reductions (10.32 vs. 7.59, p=0.079) and
statistically … Patients who finished this tailored
intervention demonstrated statistically significant, sustained
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - neurobehavioral disorder, with a
prevalence that has increased since the 1990s.1 In the United States, there are significant … of children 4
through 17 years of age have been diagnosed with ADHD as of 2011; however, there is
significant … The significant geographic
variations in care likely reflect differences and uncertainty in care delivery … There were no other significant changes to the KQs or
proposed methods. … These studies had significant flaws that might have
invalidated the results.