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Total Results: 1,182 records

Showing results for "statistically significant".

441. Total Worker Health® (TWH) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
     April 01, 2016 - A study assessed as high risk of bias has significant risk of bias (e.g., stemming from serious errors … chronic diseases, they concluded that little or no evidence shows that integration itself confers a significant … about the positive effects of TWH interventions or summarized benefits using primarily numbers of statistically … significant outcomes across studies; they generally did not consider study limitations, directness … Furthermore, among studies eligible for KQ 2, many had methodological drawbacks that introduced significant

442. Evidence Report No. 222, Data Linkage Strategies To Advance Youth Suicide Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research.pdf
     October 01, 2016 - Mental Health (NIMH)-funded Clinical Trials], the widespread data sharing by research communities adds significant … Researchers typically look for a significant interaction term followed by probes to determine whether

443. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
     January 01, 2015 - The JDRF (formerly the Juvenile Diabetes Research Foundation) has committed significant resources to … Significant HbA1c reductions observed over the 39 weeks of the study ranged from a “mean of 1.4% to … Two dosages were used and both (40 mcg/day and 60 mcg/day mini-pumps) reportedly showed statistically … significant results versus control group and were well tolerated. … Patients who had HbA1c levels “above 8.5%” had statistically significant “mean reductions up to 2.1%

444. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - weeks of triple therapy with boceprevir using a low dose of ribavirin to be associated with a non–statistically … significant trend toward lower likelihood of SVR (36% vs. 50%, RR 0.71, 95% CI 0.39 to 1.3) Triple … 2 trials found no statistically significant difference in risk of any assessed adverse event. 24-week … significant trend toward lower likelihood of SVR (36% vs. 50%, RR 0.71, 95% CI 0.39 to 1.3) Triple … 2 trials found no statistically significant difference in risk of after 3/25/2014): "WARNING: Serious

445. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
     December 01, 2015 - weeks of triple therapy with boceprevir using a low dose of ribavirin to be associated with a non–statistically … significant trend toward lower likelihood of SVR (36% vs. 50%, RR 0.71, 95% CI 0.39 to 1.3) Triple … 2 trials found no statistically significant difference in risk of any assessed adverse event. 24-week … significant trend toward lower likelihood of SVR (36% vs. 50%, RR 0.71, 95% CI 0.39 to 1.3) Triple … 2 trials found no statistically significant difference in risk of after 3/25/2014): "WARNING: Serious

446. Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
     February 01, 2012 - All other adverse events were not significant (low SOE) or had insufficient evidence. … • PDDs: For PDDs, no statistically significant difference was observed between FGAs and SGAs for … Medication adherence was not statistically or clinically different between SGAs and placebo for both … Medication adherence was statistically significantly better for placebo than for SGAs (RR, 2; 95% CI … Negotiations with the holders of the secondary data may take significant time.

447. Disposition of Comments for CER 196 The Role of Immunotherapy in the Treatment of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-disposition-comments-immunotherapy-asthma.pdf
     March 23, 2018 - Why is it only moderate strength when all of the cited studies show significant reduction and two have … The strength of evidence considers several domains and is not based solely on statistically significance … Response TEP #1 Results Page 28, line 34: “The second RCT found statistically … significant improvement in asthma symptoms with a decrease of 0.41 in ACQ score.”.

448. Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
     January 01, 2023 - Definition Alcohol-use disorder (DSM-5)5 A maladaptive pattern of alcohol use leading to clinically significant … A maladaptive pattern of alcohol use leading to clinically significant impairment or distress, as manifested … of treatment, which can be subsumed under the concept of harm reduction.31 These measures include significant … Furthermore, during the COVID-19 pandemic, researchers at RTI International found significant increases … A study assessed as high risk of bias has significant risk of bias (e.g., stemming from serious issues

449. Disposition of Comments for CER 177 Agitation Aggression Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_disposition-comments.pdf
     March 21, 2016 - Additionally, in some cases, authors inappropriately conclude differences exist when the differences are not statistically … significant. … , "Without an understanding of what constitutes a clinically meaningful change, interpretation of statistically … significant differences ... was challenging." … Yet in many places throughout the report, when a statistically significant result is noted, the phrase

450. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
     March 01, 2011 - as venous thromboembolism (VTE), affects an estimated 900,000 Americans each year and results in significant … Adverse Consequences of Venous Thromboembolism There are significant adverse consequences of DVT and … Other studies demonstrate that IVC filters are associated with significant complications, 31,32 such … These studies had significant flaws that might have invalidated the results. … which has the best confidence interval coverage for rare events, because the random effects model is statistically

451. S116 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
     October 01, 2007 - The association between long-acting benzodiazepine prescribing and APM prefer- ence was no longer significant

452. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - In trials, effects on pulmonary function were reported as early as 2 weeks, and a statistically significant … Nonetheless, cost was identified as a significant and potentially controversial issue. … Even for patients with prescription drug coverage, copayments were expected to be significant. … Patients treated with ivacaftor also demonstrated a significant improvement in quality of life (p<0.001 … COPD exacerbations can lead to significant declines in lung function and progression towards respiratory

453. Disposition of Comments Report for Evidence Report/Technology Assessment No. 214 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
     February 25, 2014 - Reviewer 10 (TEP) Introduction Page 5 vi - line 34: I am unsure what is meant by “No significant harms … If a study did not, this is a significant methodological error. … 30% (P2 = 0.30), the E + C Group would have to have > 43 patients at the follow-up assessment to be statistically … Also complete cessation is the ultimate goal but significant decrease is clinically useful. … Reviewer 12 Results In some cases, statistically significant results were ignored because they were

454. Cystic-Fibrosis-Hgh Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
     August 01, 2012 - Findings 1st Assessment: • All conclusions for KQ1-7 are still considered valid • There are no new significant … increases from baseline to 12 months ΔLBM as % total body composition was not significant. … The RR for the IGFBP remained significant. … In this trial, no significant differences were seen between the higher and the lower dose groups for … The authors of the analysis did not report p-values or whether the comparisons were statistically significant

455. Draft Comparative Effectiveness Review Appendicies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
     April 01, 2005 - One prospective nonrandomized study found a significant difference between a small decrease in … cohort studies the improved kidney function ranged from 8-51% with the majority of studies reporting statistically … and diastolic blood pressure with angioplasty, but only the change in diastolic pressure was statistically … significant. … immediate angioplasty, in contrast to those with unilateral disease, where creatinine clearance was statistically

456. Disposition of Comments for PCA3 Testing for the Diagnosis and Management of Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
     April 01, 2013 - Again, the slope is not significant (p=0.79) when 4 ‘grey zone’ studies were included. … No significant relationship was seen. … This is a significant error (Figure 9, page 41) that must be corrected in the report (if AHRQ does not … The ability to discriminate indolent from significant cancers is covered only by KQ3. … Stratification of AUC data by Progensa and other assays did not provide statistically significant evidence

457. Functional-Limitations-Horizon-Scan-High-Impact-1306 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - In phase III trials, icatibant provided significant symptom relief within about 2 hours and initial …  Key Expert Comments: Overall, experts commenting on icatibant viewed it as having significant …  Key Expert Comments: Overall, experts commenting on this intervention agreed that a significant … Results demonstrated a statistically significant reduction in the proportion of patients whose disease … Patients given both doses of dimethyl fumarate also demonstrated statistically significant reductions

458. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
     October 18, 2010 - a half a million births per year) .1 Rates of preterm birth continue to increase, resulting in a significant … with the goal of reducing neonatal morbidity and mortality by prolonging pregnancy without causing significant … Tocolytics have been shown to delay delivery 24 to 48 hours; however, significant maternal side effects … patient experiences multiple events: KQ1: bronchopulmonary dysplasia, necrotizing enterocolitis, significant … These studies have significant flaws that imply biases of various types that may invalidate the results

459. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
     January 10, 2012 - Nonbiologic systemic therapies may be effective but can be associated with significant short-term and … The study has significant flaws that imply biases of various types that may invalidate the results … comparisons. 20 The number needed to treat (NNT) or number needed to harm (NNH) will be calculated for statistically … significant results of the base case analyses for KQs 1 and 2. … A p-value of <0.05 will be considered statistically significant for all analyses.

460. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
     January 27, 2016 - I did notice inconsistency regarding including whether results were statistically significant (see … visit (0.5%; 6/1101) compared with the usual care group (0.2%; 2/861), but the difference was not statistically … significant…” Instead of stating that there was a difference but not statistically significant, the … is very wide such that we cannot conclude that there is no difference, but must conclude that a statistically … significant difference was not found.