Results

Total Results: 1,181 records

Showing results for "statistically significant".

441. S116 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
     October 01, 2007 - The association between long-acting benzodiazepine prescribing and APM prefer- ence was no longer significant

442. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
     March 01, 2011 - as venous thromboembolism (VTE), affects an estimated 900,000 Americans each year and results in significant … Adverse Consequences of Venous Thromboembolism There are significant adverse consequences of DVT and … Other studies demonstrate that IVC filters are associated with significant complications, 31,32 such … These studies had significant flaws that might have invalidated the results. … which has the best confidence interval coverage for rare events, because the random effects model is statistically

443. Cer-213-Appendix-D (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-213-appendix-d.xlsx
     January 01, 2016 - Genium 899 Many variables were statistically significant in multivariable regression analyses for different … PMID 25768067) Micropocessor vs. mechanical knee 8 Bilateral 2 Unilateral 6 0.11 0.0010 * Statistically … significant difference favoring listed component over comparator.

444. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Results – Cognitive Training Peer Reviewer #3 Table 4A.4: Presumably the results in BOLD represent statistically … and clinically significant results. … That is correct; the bold font is intended to highlight the statistically significant results. … (Bonferroni) Most were not significant even without Bonferroni corrections. … Willis, ACTIVE study investigators The impact of selective attrition, if any, can be assessed and statistically

445. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Results – Cognitive Training Peer Reviewer #3 Table 4A.4: Presumably the results in BOLD represent statistically … and clinically significant results. … That is correct; the bold font is intended to highlight the statistically significant results. … (Bonferroni) Most were not significant even without Bonferroni corrections. … Willis, ACTIVE study investigators The impact of selective attrition, if any, can be assessed and statistically

446. Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
     February 01, 2012 - All other adverse events were not significant (low SOE) or had insufficient evidence. … • PDDs: For PDDs, no statistically significant difference was observed between FGAs and SGAs for … Medication adherence was not statistically or clinically different between SGAs and placebo for both … Medication adherence was statistically significantly better for placebo than for SGAs (RR, 2; 95% CI … Negotiations with the holders of the secondary data may take significant time.

447. Disposition of Comments Report for Evidence Report/Technology Assessment No. 214 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
     February 25, 2014 - Reviewer 10 (TEP) Introduction Page 5 vi - line 34: I am unsure what is meant by “No significant harms … If a study did not, this is a significant methodological error. … 30% (P2 = 0.30), the E + C Group would have to have > 43 patients at the follow-up assessment to be statistically … Also complete cessation is the ultimate goal but significant decrease is clinically useful. … Reviewer 12 Results In some cases, statistically significant results were ignored because they were

448. Disposition of Comments for PCA3 Testing for the Diagnosis and Management of Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
     April 01, 2013 - Again, the slope is not significant (p=0.79) when 4 ‘grey zone’ studies were included. … No significant relationship was seen. … This is a significant error (Figure 9, page 41) that must be corrected in the report (if AHRQ does not … The ability to discriminate indolent from significant cancers is covered only by KQ3. … Stratification of AUC data by Progensa and other assays did not provide statistically significant evidence

449. Cystic-Fibrosis-Hgh Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
     August 01, 2012 - Findings 1st Assessment: • All conclusions for KQ1-7 are still considered valid • There are no new significant … increases from baseline to 12 months ΔLBM as % total body composition was not significant. … The RR for the IGFBP remained significant. … In this trial, no significant differences were seen between the higher and the lower dose groups for … The authors of the analysis did not report p-values or whether the comparisons were statistically significant

450. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
     October 18, 2010 - a half a million births per year) .1 Rates of preterm birth continue to increase, resulting in a significant … with the goal of reducing neonatal morbidity and mortality by prolonging pregnancy without causing significant … Tocolytics have been shown to delay delivery 24 to 48 hours; however, significant maternal side effects … patient experiences multiple events: KQ1: bronchopulmonary dysplasia, necrotizing enterocolitis, significant … These studies have significant flaws that imply biases of various types that may invalidate the results

451. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
     January 10, 2012 - Nonbiologic systemic therapies may be effective but can be associated with significant short-term and … The study has significant flaws that imply biases of various types that may invalidate the results … comparisons. 20 The number needed to treat (NNT) or number needed to harm (NNH) will be calculated for statistically … significant results of the base case analyses for KQs 1 and 2. … A p-value of <0.05 will be considered statistically significant for all analyses.

452. Alcohol-misuse-drug-therapy-140326 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
     January 27, 2012 - A maladaptive pattern of alcohol-use leading to clinically significant impairment or distress, as manifested … Alcohol dependence11 A maladaptive pattern of alcohol use, leading to clinically significant impairment … Such a review will provide significant assistance to dissemination efforts to educate U.S. clinicians … The potential to improve the health and welfare of the U.S. population could be significant as well. … A study assessed as high risk of bias has significant risk of bias (e.g., stemming from serious issues

453. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - In trials, effects on pulmonary function were reported as early as 2 weeks, and a statistically significant … Nonetheless, cost was identified as a significant and potentially controversial issue. … Even for patients with prescription drug coverage, copayments were expected to be significant. … Patients treated with ivacaftor also demonstrated a significant improvement in quality of life (p<0.001 … COPD exacerbations can lead to significant declines in lung function and progression towards respiratory

454. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - in which aspirin was used for primary prevention in patients with vascular disease did not find a statistically … significant benefit.19 The CAPRIE (clopidogrel versus aspirin in patients at risk of ischaemic events … First, there were significant intertrial variations in the control groups, the types and duration of … most recent Cochrane review, performed in 2008, compared exercise training to usual care.22 It found statistically … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug

455. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
     December 20, 2011 - 2008 Institute of Medicine (IOM) report on the treatment of PTSD, the condition “…develops in a significant … trauma • Failure to recall an important aspect of trauma • Loss of interest or participation in significant … of disturbance • Duration of disturbance symptoms is more than 1 month Criterion F: Clinically significant … distress or impairment • Disturbance causes clinically significant distress or impairment in social … A “poor” study has significant bias (e.g., stemming from serious errors in design or analysis) that

456. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
     April 01, 2013 - Potential for significant health impact • Potential for significant health impact: − To improve … − To reduce significant variation related to quality of care. … • Potential for significant economic impact, reducing unnecessary or excessive costs. … Lack of a definition of “clinically significant improvement” in diagnostic accuracy. 3. … Lack of a definition of “clinically significant improvement” in diagnostic accuracy. 3.

457. Functional-Limitations-Horizon-Scan-High-Impact-1306 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - In phase III trials, icatibant provided significant symptom relief within about 2 hours and initial …  Key Expert Comments: Overall, experts commenting on icatibant viewed it as having significant …  Key Expert Comments: Overall, experts commenting on this intervention agreed that a significant … Results demonstrated a statistically significant reduction in the proportion of patients whose disease … Patients given both doses of dimethyl fumarate also demonstrated statistically significant reductions

458. Draft Comparative Effectiveness Review Appendicies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
     April 01, 2005 - One prospective nonrandomized study found a significant difference between a small decrease in … cohort studies the improved kidney function ranged from 8-51% with the majority of studies reporting statistically … and diastolic blood pressure with angioplasty, but only the change in diastolic pressure was statistically … significant. … immediate angioplasty, in contrast to those with unilateral disease, where creatinine clearance was statistically

459. Disposition of Comments for Psychological Treatments and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
     April 03, 2013 - pooled effect size with a 95% confidence interval contained completely between -.28 and +.28 (often non statistically … significant We disagree. … That would be true even if such a pooled effect size were statistically significant (e.g., the confidence … indicating the thresholds on your “tree” plots would then distinguish between two treatments that are statistically … It's short half-life can create difficulties with patient adherence and it also has significant issues

460. Disposition of Comments Report for CER 134 Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
     May 13, 2014 - To determine whether this potential population heterogeneity would have a significant impact on our … The one possible exception, that might be considered a significant change in the effect size, was for … that our meta-analyses for variation in naltrexone response related to OPRM1 polymorphisms found no statistically … We realize that this outcome in this study was statistically significant. … As presently offered, this report is not likely to generate significant interest.