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effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
April 01, 2013 - Intermediate health outcomes showed
significant reductions in distal embolization and
no reflow, and … in mortality risk, although a single
trial found a significant reduction in MACE. … Intermediate health outcomes showed significant reductions
in distal embolization and no reflow, and … in mortality risk, although a single
trial found a significant reduction in MACE. … The only significant finding was increased time to perform a
PCI procedure compared with control for
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review
Comparative Effectiveness Review
Number 272
Genitourinary Syndrome of
Menopause: A Systematic Review
Executive Summary
Main Points
• One hundred seven publications of hormonal, non-hormonal moisturiz…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
June 15, 2010 - and Objectives for the Systematic Review
Depression is a complex mental illness that can result in significant … The results
suggest a modest and statistically significant advantage for remission rates when switching … We will
evaluate the extent of statistical heterogeneity using a Chi-square (statistically significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - eligible studies identified.c
remission
rTMS vs. sham Maintenance of 68 Insufficient 3 fair trials: no significant … Cognitive 22 Insufficient 1 fair trial: no significant differences in ECT
+ rTMS functioning a single … whereas some evidence suggests that
rTMS improves cognitive functioning
compared to sham (2 trials: significant … Adverse events 22 Low 1 fair trial: no significant differences in
ECT + rTMS specific adverse events … Three fair trials compared rTMS
with a sham procedure and found no significant
differences.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
January 01, 2014 - This significant reduction
was observed in RCTs, but not observed in nonrandomized comparative studies … there was moderate evidence (drawn from 9 RCTs and 22
nonrandomized studies) that fails to support a statistically … MACE is considered a secondary
endpoint in this trial, estimates of which are similar and statistically … Importance:
• Represents a significant disease burden, large proportion or priority population. … Potential Impact:
• Potential for significant health impact, significant economic impact, potential
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
March 01, 2012 - Negotiations with the holders of the secondary data may take significant time. … Unlikely to have
significant constraints on
sample size. … Negotiations with the holders of the secondary data may take significant time. … Negotiations with the holders of the secondary
data may take significant time. … characteristics, or, commonly, differences in co-interventions
which may be difficult to adjust for statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
October 01, 2014 - did not demonstrate superiority of mifepristone over
placebo.11 However, phase III data revealed a statistically … significant linear association between
mifepristone plasma concentration and clinical response. … their plasma
that was greater than the 1660 nanogram per milliliter threshold mentioned above,
statistically … Therefore, the expected change in upfront costs
might be less significant than these experts believe … This
statistically significant superiority was maintained 7 days after administration.88
Several
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effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
January 01, 2012 - The Juvenile Diabetes Foundation has committed significant resources to developing a
system, and systems … Key Expert Comments: Overall, experts commented that a CLS has significant potential to
simplify … Additionally, experts indicated that these systems would likely need significant upkeep by
users and … While experts thought that the initial use of
these systems would be limited, they saw significant … Authors
reported, “Trial A and B data combined demonstrated a statistically significant effect at week
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - For example, significant differences
favoring an intervention for efficacy outcomes or
nonsignificant … of outcomes data from small studies
15
when those findings, if reported, would be either not statistically … consistently find that an intervention
improves an outcome (e.g., apnea-hypopnea index is reduced by a statistically … This should not be misunderstood to mean that all statistically
nonsignificant effects should lead to … when the number of available trials is large, then the test
becomes overly sensitive.1 Furthermore, a statistically
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
January 01, 2010 - The most recent Cochrane review of continuous labor
support found a significant reduction in cesarean … We do
define "same" as not statistically different across the
intervention and comparison arms in each … concur
that it is harder to dismiss the potential for benefit of a
strategy that did not provide statistically … There were no statistically meaningful assessments of risk
of harms from these techniques in the included … It is a short step
from "no statistically significant difference" to "this
intervention is safe."
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
February 26, 2013 - Peer Reviewer 6 Results page 20 line 5: “Significantly” should read significant Edited. … Our
review addresses the question of stenting a
functionally significant stenosis for the
comparison … These tools offer
significant benefits which should be elucidated with respect to
their ability to … The DEFER study demonstrates the significant positive
impact of utilizing FFR in assessing lesions and … At two years, there
was also a significant benefit in terms of anginal class in favor
of the Defer
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-213-appendix-d.xlsx
January 01, 2016 - Genium 899 Many variables were statistically significant in multivariable regression analyses for different … PMID 25768067) Micropocessor vs. mechanical knee 8 Bilateral 2 Unilateral 6 0.11 0.0010
* Statistically … significant difference favoring listed component over comparator.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
June 01, 2010 - Many of the differences were statistically significant in this large cohort, although the clinical … In our model, the ICD-9-based ―obesity EDC‖ had a very significant and sizable
predictive coefficient
-
effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
May 04, 2017 - We repeated the calculations
of effect sizes and did not
find significant differences. … significant difference in
baseline values. … from the pooled analysis, we
did note that it was an outlier
and was responsible for the
lack of a statistically … significant improvement in
WOMAC pain and function
with strength training. … difference in varus moment during
stance, and Nadaud et al. demonstrated
significant medial condylar
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
May 04, 2017 - We repeated the calculations
of effect sizes and did not
find significant differences. … significant difference in
baseline values. … from the pooled analysis, we
did note that it was an outlier
and was responsible for the
lack of a statistically … significant improvement in
WOMAC pain and function
with strength training. … difference in varus moment during
stance, and Nadaud et al. demonstrated
significant medial condylar
-
effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - Results –
Cognitive
Training
Peer Reviewer #3 Table 4A.4: Presumably the results in BOLD
represent statistically … and clinically significant results. … That is correct; the bold font is intended to
highlight the statistically significant results. … (Bonferroni)
Most were not significant even without
Bonferroni corrections. … Willis,
ACTIVE study
investigators
The impact of selective attrition, if any, can be
assessed and statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - Results –
Cognitive
Training
Peer Reviewer #3 Table 4A.4: Presumably the results in BOLD
represent statistically … and clinically significant results. … That is correct; the bold font is intended to
highlight the statistically significant results. … (Bonferroni)
Most were not significant even without
Bonferroni corrections. … Willis,
ACTIVE study
investigators
The impact of selective attrition, if any, can be
assessed and statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
November 01, 2012 - Nonbiologic systemic therapies
may be effective but can be associated with significant
short-term and … The other statistically
significant difference in DLQI was in patients who had
PASI 50 to 75 compared … Together, these factors precluded the ability to statistically
pool data. … therefore, we
could not determine whether the difference in change
between the treatment groups was significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
February 01, 2012 - significant. … study would be whether the interaction term
(between the main effect and the predictor variable) is statistically … significant. … of interest in such a RCT would be whether the compliance with CPAP,
MAD, or other treatments is statistically … Potential for significant health impact:
- To improve health outcomes
- To reduce significant variation
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
March 01, 2021 - Evidence Summary: Comparative Effectiveness Review No. 238: Cervical Ripening
Comparative Effectiveness Review
Number 238
Cervical Ripening in the Outpatient
Setting
Evidence Summary
Main Points
• The highest strength of evidence for outcomes of outpatient cervical ripening
found in this report was low, with …