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Total Results: 1,181 records

Showing results for "statistically significant".

401. Disposition of Comments for CERs 155 156 Contast-Induced Nephropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
     January 07, 2016 - No statistically significant associations were found.” 28 Technical Expert #2 Discussion/ Conclusion … Was the finding statistically significant or not? … in the Executive Summary to read: “indicating a small effect that is clinically unimportant and statistically … There are neither significant changes nor omissions that should be made. … The change at 48 hours was not significant in this paper (absolute change-2.36%) which would be the

402. Pharmacologic and Nonpharmacologic Treatments of Post-Traumatic Stress Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol.pdf
     July 10, 2018 - indirect exposure to trauma such as actual or threatened death, injury, or sexual violence.1 PTSD has significant … Fourth, outcomes reported may be statistically significant but not clinically meaningful, may not correlate … with functional improvements or loss of PTSD diagnosis, or may obscure clinically significant effects … e.g., change in total PTSD symptom severity score, diagnostic change, meaningful/reliable/clinically significant … Other reported cutoff for meaningful change (e.g., reliable change index, clinically significant change

403. Pharmacologic and Nonpharmacologic Treatments of Post-Traumatic Stress Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-protocol.pdf
     July 10, 2018 - indirect exposure to trauma such as actual or threatened death, injury, or sexual violence.1 PTSD has significant … Fourth, outcomes reported may be statistically significant but not clinically meaningful, may not correlate … with functional improvements or loss of PTSD diagnosis, or may obscure clinically significant effects … e.g., change in total PTSD symptom severity score, diagnostic change, meaningful/reliable/clinically significant … Other reported cutoff for meaningful change (e.g., reliable change index, clinically significant change

404. Association Between Outcomes and Dental Services in People Receiving Treatments That Cause Medication-Related Osteonecrosis of the Jaw: A Rapid Response Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
     May 01, 2025 - • Four large retrospective cohort studies of fair quality demonstrated a statistically significantly … of tooth extractions.42,43 Two smaller cohort studies of fair quality (N = 75 and 115) reported no significant … Both RCTs found no significant difference regarding MRONJ incidence and mucosal integrity between surgical … significant.45 Table 7. … Data from four large retrospective cohort studies showed statistically significantly increased risk

405. Disposition of comments_Comparative Effectiveness Review No. 244: Safety of Vaccines Used for Routine Immunization in the United States: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
     May 25, 2021 - While we generally agree, none of the new risk estimates in this report are statistically significant … use of the CI to assess rare events in studies that are inadequately powered or designed to detect statistically … significant differences and to describe how the analysis of “increased risk” may not be as useful … TEP #5 General Additionally, the methods used to combine studies and statistically analyze the results … “results was not statistically significant”. Should be “results were...”

406. Attention Deficit Hyperactivity Disorder: Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
     October 01, 2011 - Social Burden Throughout childhood and adolescence, clinically significant ADHD is often associated … Symptoms are clinically significant when they cause impaired functioning; they generally interfere … However, teacher­reported outcomes do not document a statistically significant superiority of ATX over … Significant regional variations are noted within the United States. … An analysis of the significant variation in psychostimulant use across the U.S.

407. Assessing the Quality of Individual Studies (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
     January 01, 2010 - Decisions made at the time of quality assessment may have significant consequences for the review, depending … Attributes of Poor-Quality Studies Significant biases Inappropriate design, conduct, analysis, or reporting

408. Disposition of Comments Report for Screening, Behavioral Counseling, and Referral in Primary Care To Reduce Alcohol Misuse (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_disposition-comments.pdf
     July 10, 2012 - significant difference for evidence of benefit for heavy episodes. … significant using appropriate statistics for highly skewed data?). … significant) to understand the range of potential benefits and harms? … significant for that study (WMD, -0.2, 95% CI, -8.9 to 8.6). … significant between the two groups.

409. Disposition of Comments Report for Pressure Ulcer Risk Assessment and Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
     May 08, 2013 - #2 Results The authors often use the term “trend” to refer to situations where a result was not statistically … significant at the conventional 5% level. … significant in one trial. … risk (RR 0.92), and the other trials were small, with imprecise estimates, with only one showing a statistically … significant reduction in risk of ulcers.

410. Disposition of Comments Report for Procalcitonin-Guides Antibiotic Therapy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
     October 05, 2012 - , (actually only four studies provided evidence and table 7 says 5 studies), two studies reported significant … difference and two studies reported non- significant difference – how do the investigators conclude … Tract Infections Another example of grading evidence: ICU admission – none of the studies reported significant … information to perform meta-analysis using 3 of 5 studies that reported antibiotic duration, showing a significant … reporting on this outcome provided sufficient information to be included in meta-analysis, yielding a significant

411. Crosscutting-Horizon-Scan-High-Impact-1406 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - they were unsure whether the potential benefits of wider access to propofol-mediated sedation were significant … administration of propofol by such teams during routine endoscopy cases, which could represent a significant … On the primary endpoint, patients receiving the Sedasys-delivered propofol had a statistically lower … Acceptance and adoption: Significant controversy surrounds the adoption of Sedasys- delivered propofol … Despite this, outcomes at 30 days were not statistically different between groups in unadjusted analysis

412. Disposition of Comments for Evidence Report 224 Omega-3 Fatty Acids (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
     October 12, 2016 - We now present the results of Egger's and Begg’s tests for outcomes that are significant. … We have added Egger's and Begg’s statistics for significant findings. … We have now calculated publication bias for all pooled analyses that showed significant effect sizes … It could be that the authors were using the term "non- significant" to mean "minor" or "not significant … We've gone through the report and removed the term “non-significant.”

413. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - Heterogeneity will be considered statistically significant when the p-value of the Q statistic is P< … We will not combine the results of randomized and non-randomized studies statistically. … often referred to as tests for publication bias; reasons other than publication bias can lead to a statistically … significant result, including “true” heterogeneity between smaller and larger studies, other biases

414. Disposition of Comments_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
     May 14, 2025 - One small comment is on this sentence: “Collectively, primary RCT authors reported a statistically … significant reduction in cancer mortality in nine of the trials and a reduction in late-stage cancer … review authors calculated a statistically significant reduction in cancer mortality from screening … Review authors also calculated a statistically significant reduction in Stage III or IV cancer in … I found no significant technical issues with the methodology and findings.

415. Ptsd-Adults-Trauma-Interventions Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
     April 01, 2013 - Prevention of PTSD can potentially reduce a significant burden of individual and societal suffering. … Studies assessed as high risk of bias have significant flaws of various types (stemming from serious … statistical approaches for data analysis (e.g., lack of ITT analysis, or lack of statistical adjustment for significant

416. Migraine-Emergency Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
     November 01, 2012 - 0.43 to 1.14) Headache recurrence (30 days) Dexamethasone vs. placebo (1 RCT) Insufficient No significant … Neither trial found a statistically significant difference in the occurrence of akathisia (Table D … comparisons were repeated in this review and, while a similar trend was observed, the differences were not statistically … significant. … Metoclopramide + anticholinergic vs. phenothiazine + anticholinergic (1 RCT) Insufficient No significant

417. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - Intermediate health outcomes showed significant reductions in distal embolization and no reflow, and … in mortality risk, although a single trial found a significant reduction in MACE. … Intermediate health outcomes showed significant reductions in distal embolization and no reflow, and … in mortality risk, although a single trial found a significant reduction in MACE. … The only significant finding was increased time to perform a PCI procedure compared with control for

418. Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
     July 01, 2024 - Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review Comparative Effectiveness Review Number 272 Genitourinary Syndrome of Menopause: A Systematic Review Executive Summary Main Points • One hundred seven publications of hormonal, non-hormonal moisturiz…

419. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
     September 01, 2011 - eligible studies identified.c remission rTMS vs. sham Maintenance of 68 Insufficient 3 fair trials: no significant … Cognitive 22 Insufficient 1 fair trial: no significant differences in ECT + rTMS functioning a single … whereas some evidence suggests that rTMS improves cognitive functioning compared to sham (2 trials: significant … Adverse events 22 Low 1 fair trial: no significant differences in ECT + rTMS specific adverse events … Three fair trials compared rTMS with a sham procedure and found no significant differences.

420. Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
     January 01, 2014 - This significant reduction was observed in RCTs, but not observed in nonrandomized comparative studies … there was moderate evidence (drawn from 9 RCTs and 22 nonrandomized studies) that fails to support a statistically … MACE is considered a secondary endpoint in this trial, estimates of which are similar and statistically … Importance: • Represents a significant disease burden, large proportion or priority population. … Potential Impact: • Potential for significant health impact, significant economic impact, potential