-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
May 01, 2013 - day nearly every day (as
indicated by either subjective account
or observation made by others)
• Significant … OR = odds ratio; SOE = strength of evidence
Among potential maternal demographic risk factors, no
statistically … significant association was found between
postpartum depression and maternal age, education,
income … One study did, however,
find a significant association between maternal
unemployment and postpartum … -based study that demonstrated high rates
of receipt of appropriate services and significant reductions
-
effectivehealthcare.ahrq.gov/sites/default/files/methods-report-web-interactive-presentation-appendix-a.pdf
May 29, 2025 - satisfaction and, with one exception
(combination of neuromodulation with
behavioral therapy [G+H]), statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
January 01, 2023 - Breast Irradiation for
Breast Cancer
Executive Summary
Main Points
• There was no significant … However, significant
variation in patient selection, treatment technique, and reported clinical outcomes … There was no significant difference between PBI and WBI in terms of IBR, overall
survival, and cancer-free … There were no significant differences in IBR or other
outcomes according to patient, tumor, and treatment … The finding of reduced acute toxicity with PBI represents a significant finding
that will meaningfully
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
January 17, 2017 - It also shows that no significant new
conclusions can be drawn.
Thank you for your comments. … Writing a piece that will have
impact on policy decision making may mean that a
significant group of … Differences in the 3rd follow-up year were
in the same direction but not significant. … first RCT (and not
large enough, in the authors' view, to warrant
tonsillectomy), but nonetheless statistically … significant
during each of the 3 years of follow-up.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_disposition-comments.pdf
July 10, 2012 - significant difference for evidence
of benefit for heavy episodes. … significant
using appropriate statistics for highly skewed data?). … significant) to understand the range of potential benefits
and harms? … significant
for that study (WMD, -0.2, 95% CI, -8.9 to
8.6). … significant between the two groups.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
May 01, 2025 - • Four large retrospective cohort studies of fair quality demonstrated a statistically
significantly … of tooth extractions.42,43
Two smaller cohort studies of fair quality (N = 75 and 115) reported no significant … Both RCTs found no significant
difference regarding MRONJ incidence and mucosal integrity between surgical … significant.45
Table 7. … Data from four large retrospective cohort studies showed statistically significantly
increased risk
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-protocol.pdf
July 10, 2018 - indirect exposure to trauma such as actual or
threatened death, injury, or sexual violence.1 PTSD has significant … Fourth, outcomes reported may be statistically significant but not clinically
meaningful, may not correlate … with functional improvements or loss of PTSD diagnosis, or may
obscure clinically significant effects … e.g., change in total PTSD symptom severity score, diagnostic change,
meaningful/reliable/clinically significant … Other reported cutoff for meaningful change (e.g., reliable change index, clinically
significant change
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol.pdf
July 10, 2018 - indirect exposure to trauma such as actual or
threatened death, injury, or sexual violence.1 PTSD has significant … Fourth, outcomes reported may be statistically significant but not clinically
meaningful, may not correlate … with functional improvements or loss of PTSD diagnosis, or may
obscure clinically significant effects … e.g., change in total PTSD symptom severity score, diagnostic change,
meaningful/reliable/clinically significant … Other reported cutoff for meaningful change (e.g., reliable change index, clinically
significant change
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
May 14, 2025 - One small comment is on this
sentence: “Collectively, primary RCT
authors reported a statistically … significant
reduction in cancer mortality in nine of the
trials and a reduction in late-stage cancer … review authors calculated a statistically
significant reduction in cancer mortality from
screening … Review
authors also calculated a statistically
significant reduction in Stage III or IV cancer
in … I found no significant
technical issues with the methodology and
findings.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
November 01, 2012 - 0.43 to 1.14)
Headache recurrence
(30 days)
Dexamethasone vs. placebo
(1 RCT)
Insufficient No significant … Neither trial found a statistically
significant difference in the occurrence of akathisia
(Table D … comparisons were repeated
in this review and, while a similar trend was observed, the
differences were not statistically … significant. … Metoclopramide + anticholinergic
vs. phenothiazine + anticholinergic
(1 RCT)
Insufficient No significant
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
May 25, 2021 - While we generally agree, none of
the new risk estimates in this report
are statistically significant … use of
the CI to assess rare events in studies
that are inadequately powered or
designed to detect statistically … significant differences and to describe
how the analysis of “increased risk”
may not be as useful … TEP #5 General Additionally, the methods used to
combine studies and statistically
analyze the results … “results was not
statistically significant”. Should be
“results were...”
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
October 01, 2011 - Social Burden
Throughout childhood and adolescence, clinically
significant ADHD is often associated … Symptoms
are clinically significant when they cause impaired
functioning; they generally interfere … However, teacherreported outcomes
do not document a statistically significant superiority of
ATX over … Significant regional variations are noted within the United States. … An analysis of the
significant variation in psychostimulant use across the
U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
January 01, 2010 - Decisions made at the time of quality assessment may have significant consequences for the review, depending … Attributes of Poor-Quality Studies
Significant biases
Inappropriate design, conduct, analysis, or reporting
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - Effects
were statistically comparable, but the trial was not
powered to show equivalence or noninferiority … Both were statistically
comparable in this small trial. … a dose of 1.95 to 4.5 grams per day for 4 to 5 days
from the onset of bleeding led to a clinically significant … In head-to-head comparisons with
statistically significant differences, the LNG-IUS has
one trial showing … disease, thyroid disease,
abnormal cervical cytology, noncyclic bleeding, history
or presence of significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
May 08, 2013 - #2
Results The authors often use the term “trend” to refer to situations
where a result was not statistically … significant at the
conventional 5% level. … significant in one trial. … risk (RR 0.92), and the other trials
were small, with imprecise estimates, with only one showing
a statistically … significant reduction in risk of ulcers.
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
June 01, 2014 - they were unsure whether the potential benefits of wider access to
propofol-mediated sedation were significant … administration of propofol by such teams during routine endoscopy
cases, which could represent a significant … On
the primary endpoint, patients receiving the Sedasys-delivered propofol had a statistically lower … Acceptance and adoption: Significant controversy surrounds the adoption of Sedasys-
delivered propofol … Despite this, outcomes at 30 days were not statistically different between
groups in unadjusted analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
October 05, 2012 - , (actually only four studies provided evidence
and table 7 says 5 studies), two studies reported
significant … difference and two studies reported non-
significant difference – how do the investigators conclude … Tract Infections
Another example of grading evidence: ICU admission –
none of the studies reported significant … information to perform meta-analysis using 3 of 5 studies
that reported antibiotic duration, showing a significant … reporting on this outcome provided sufficient
information to be included in meta-analysis, yielding a significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
December 09, 2013 - Heterogeneity will be considered statistically significant when the p-value of the Q
statistic is P< … We will not combine
the results of randomized and non-randomized studies statistically. … often referred
to as tests for publication bias; reasons other than publication bias can lead to a
statistically … significant result, including “true” heterogeneity between smaller and larger
studies, other biases
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
October 12, 2016 - We now present the results of Egger's
and Begg’s tests for outcomes that are
significant. … We have added Egger's and Begg’s
statistics for significant findings. … We have now calculated publication bias
for all pooled analyses that showed
significant effect sizes … It
could be that the authors were using the term "non-
significant" to mean "minor" or "not significant … We've gone through the report and
removed the term “non-significant.”
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
April 01, 2013 - Prevention of PTSD can potentially reduce a significant
burden of individual and societal suffering. … Studies
assessed as high risk of bias have significant flaws of
various types (stemming from serious … statistical approaches for data analysis (e.g.,
lack of ITT analysis, or lack of statistical adjustment for
significant