-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - Poor-quality studies have significant flaws that may
invalidate the results. … populations likely to be targeted by
screening, whether differences in outcomes were
clinically (as well as statistically … genotype 4
infection found dual therapy with pegylated interferon alfa-2a
plus ribavirin associated with statistically … triple therapy with boceprevir using a low dose of ribavirin
(400-1,000 mg daily) associated with a non–statistically … Therapy With Pegylated Interferon Alfa-2a or Alfa-2b Plus Ribavirin
Harms In two trials, there were no statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - significant. … Effect size: None (i.e., no effect/no statistically significant effect), small, moderate, or large increased … Effect size: None (i.e., no effect/no statistically significant effect), small, moderate, or large increased … Findings that were not statistically significant were interpreted as follows:
• In determining the strength … significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-adults-prisons_research-protocol.pdf
September 13, 2012 - This definition aids interpretation in two main ways: (1) to determine
whether a statistically significant … difference is clearly clinically significant, and
(2) to determine whether a statistically nonsignificant … difference is small enough to
exclude the possibility of a clinically significant difference. … corresponds to a
Hedges’ g of 0.2, using the formula recommended by Sánchez-Meca.40 For suicide, any
statistically … significant difference will meet the standard of a clinically significant
difference.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
January 01, 2020 - I would comment that
there appears to be significant duplication in content
between the very extensive … Two of the RCTs showed no difference, while two
RCTs (including Crowther) showed a significant
difference … pregnancy outcomes in the absence of treatment,
the ability of a study or pooled analysis to find a
statistically … significant difference in pregnancy
outcomes appears more dependent on study
design, in particular … Peer Reviewer
#9
Results Again--KQ3 has lots or significant RR despite the "low"
quality.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
May 01, 2025 - controls who
would have otherwise been eligible
but who did not receive an MCST;
this finding was not statistically … significant (odds ratio, 1.58; 95%
confidence interval, 0.47 to 5.31).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - • Patients treated with BT and standard care (medical
management) showed statistically greater improvements … • Patients treated with BT and standard care used
statistically significantly less rescue medication … • Patients treated with BT and standard care experienced
statistically significantly fewer exacerbations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
June 10, 2013 - defined precision for a body of evidence as at least 70% of the
outcomes in the same direction (whether statistically … significant or not). … data
on BMI
“Of the three studies reported above that measured change in BMI, all three
showed a statistically … effect and highly significant pooled effect. … We added this in our Discussion:
What is a meaningful difference (i.e., effect size) versus statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - acid
suppression medications.16-25 Risk profiles for recurrent
CDI are similar.21 One study, which statistically … For initial cure, no significant difference was observed,
regardless of strain. … For example, minimum
datasets might be those that would yield statistically
significant results in a … • No significant differences in outcomes, including initial
cure, clinical recurrence, and mean days … Significant
impact of terminal room cleaning with bleach on
reducing nosocomial Clostridium difficile
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
January 01, 2017 - allopurinol 1 RCT 2269 No difference in serum urate-lowering effect ���
1 systematic review NR No statistically … significant differences in overall adverse events ���
Subgroup of 1 RCT 2269 Age and race do not affect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
November 07, 2023 - Drinking days Consider rephrasing as "Evidence for a reduction in drinking
days was insufficient, with no statistically … significant difference in drinking days
(p=0.2) reported in one trial conducted in Thailand that was … Can it be rewritten as "a significant interaction between naltrexone
and CBI"? … More significant
cognitive impairment is often a reason that patients report discontinuing topiramate … Subsequent
meta-analyses (e.g., https://pubmed.ncbi.nlm.nih.gov/25767129/) did not show
significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-protocol.pdf
July 01, 2023 - The report did note that three studies that used a continuous
monitoring intervention found significant … systematic review by Cardona-Morrell found that intermittent monitoring systems were
associated with a statistically … significant reduction in mortality, while continuous monitoring
systems were not.13 Heterogeneity … monitoring study)10, 11, 15, 16 reported average hospital length of stay, and three
of these found a significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-disposition-comments.pdf
January 01, 2020 - in
BFHI certified facilities than those in non-certified
facilities, although differences were not statistically … significant.” … TEP Reviewer 8 Results p 19 l 25-30: In citations 66 and 67, the results
appear to be statistically … significant. … significant.”
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - People
may read this sentence and assume these are
significant findings and therefore choose not to … These are indeed all statistically significant
associations, but statistical significance
does not … To the average reader, “harms” tend
to be major and significant. … Otherwise readers will assume that this is a significant
reason to avoid treatment. … We don’t think it is clinically significant, but
it is statistically significant, which is why we
suggest
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - Poor (high risk of bias) These studies have significant flaws that imply biases of various types
that … Statistical heterogeneity will be addressed using Q Statistic (a p-value <0.10 considered
representative of significant … A p-value of Statistic (a p-value <0.05 will be considered statistically significant
for all analyses
-
effectivehealthcare.ahrq.gov/products/transparency-reporting/overview
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
September 28, 2015 - found that only two quadratic
loops (of a total of 43 total quadratic and triangular
loops) showed statistically … significant inconsistency.” … found that only two quadratic loops
(of a total of 43 total quadratic and triangular
loops) showed statistically … Peer Reviewer 4 Results Also most MDs are not statistically significantly different
from 0 (not different … significant in the network
meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-addendum-140619.pdf
June 19, 2014 - Insufficient (No
studies)
CV: SOE=
Moderate (2
studies, 268
patients)
Both studies
demonstrated
significant … Transcatheter
PVI Without
CFAE
Ablation
SOE=Low
(2 studies,
247
patients)
2 studies
showing
significant … Insufficient (No
studies)
SOE=
Insufficient (No
studies)
SOE=Low (2
studies, 152
patients)
No significant … studies,
181
patients)
OR 12.30
(95% CI,
1.31 to
115. 29)
demonstra
ting
statisticall
y
significant … SOE=High (8
studies, 632
patients)
OR 7.94
(95% CI, 3.63
to 17.36)
demonstratin
g large and
significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
October 01, 2012 - studies contributed data for many of the comparisons
and outcomes; therefore, results that showed no statistically … pregnancy outcomes in the absence of treatment, the
ability of a study or pooled analysis to find a statistically … For Key Question 3,
many of the statistically significant differences seemed
to be driven by the … size of the study or pooled analysis
(i.e., statistically significant differences could be found
if … significant differences were found.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - These studies reported only 14
outcomes with significant results. … Neither found any significant
differences. … There appears to be a statistically nonsignificant trend in
the NRCSs, which favor no ear plugs and … They found significant interactions
between daycare attendance in children 3 years or younger,
and … compliance) in children who did not wear
ear plugs.18 A second RCT, with high risk of bias, found
a statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - inpatient hospital costs accounting for 70 percent of the total cost in
the first-year after stroke.2,8 Significant … experiencing an ischemic stroke as being worse than death.9 Additionally, evidence has
demonstrated the significant … Both of these clearances were granted through the FDA 510(k) process resulting in
significant controversy … mRS (≤2=good outcome, ≥3=poor outcome), NIHSS score [including a
NIHSS decrease ≥ 4 points deemed significant