-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_executive.pdf
May 01, 2014 - significant reduction in readmission rate or mortality compared with usual care), - indicates that we … found no
benefit (i.e., no statistically significant reduction in the outcome). … bNA entry for NNT indicates that the relative risk (95% CI) was not statistically significant, so we … communication; our subgroup analyses for reduction in
all-cause readmissions and mortality found no statistically … significant difference by method of communication at any
outcome timepoint.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - No significant difference
for PANSS (low SoE, 20 RCTs). … For all significant findings, the
SGA was preferred. … Perphenazine vs. quetiapine No significant difference in HRQoL (1 RCT). … Perphenazine vs. ziprasidone No significant difference in HRQoL (1 RCT). … Overall, there were few significant
differences of clinical importance.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
December 05, 2013 - Key Expert Comments: Overall, experts commenting on this intervention stated that a
significant … Unmet need and health outcomes: Multilevel DDD presents a significant unmet need for new
treatment … Statistically significant
improvements in the WOMAC and Numeric Rating Scale scores were observed in … who were treated with three intra-articular PRP
injections every 2 weeks, 6-month followup showed statistically … Statistically significant improvements in all clinical scores (International Knee
Documentation Committee
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
February 01, 2012 - Studies showed no significant
difference for depression and a significant difference for
mania favoring … SGA (3 RCTs, 1 PCS) Low No significant difference.
symptoms
Clozapine vs. olanzapine Low No significant … ) Low No significant difference. … Low No significant difference.
(1 RCS, 1 PCS)
Olanzapine vs. quetiapine Moderate Significant effect … No significant difference.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
January 01, 2010 - The overlap between the groups is excellent
and suggests that the propensity score approach is statistically … The adjusted mortality difference was statistically
significant in the initial six months post-PCI, … No significant differences were found for any of the remaining diagnoses. … might have conferred a bleeding disadvantage, as has been
seen in other studies;38,39 however, no statistically … significant difference was observed in
our population.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
April 01, 2025 - and intermittent explosive
disorder (IED), and studies in children and adolescents with clinically significant … enhanced treatment more effective at reducing disruptive behavior,
although the findings were not always statistically … significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - placebo in one study, leflunomide
produced better improvement in health-related quality
of life and statistically … significant, but not clinically
significant, improvement in disease activity and functional
capacity … leflunomide led to higher rates of withdrawals
because of adverse events, diarrhea, and
clinically significant … Important Differences (MCIDs): ACR 20 is 20% minimal improvement;ACR 50/70 considered more clinically significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
May 01, 2022 - significant; the difference was
moderate and statistically
significant on day 4. … significant decrease in
pain intensity at <1 day, with no
difference at 1 day to 1 week. … significant (median 15 vs. 20 mg,
p=0.49). … significant (2.42 vs. 3.26 on a 0 to 10 VAS, p=0.09). … significant (p=0.81).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
July 01, 2009 - Nonoverlapping confidence
intervals, significant unexplained clinical or statistical heterogeneity, … EPCs should designate an evidence base as inconsistent when different studies show
statistically significant … mortality, which was lower by
one patient per 100 treated (i.e., 1 percent), a difference that was not statistically … significant (95-
percent confidence interval [CI], -4 percent to +3 percent). … For
example, results may be statistically
compatible with both clinically important
superiority and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
May 05, 2017 - There
is significant potential for bias. … Peer
Reviewer #1
Results Page 68
Table 10, What does
statistically significant
mean here? … added as note to Table 10 "* No statistically
significant effect of intervention on outcome (in
either … values here instead of just
NS
We have chosen to emphasize effect sizes of
results reported to be statistically … significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
May 05, 2017 - There
is significant potential for bias. … Peer
Reviewer #1
Results Page 68
Table 10, What does
statistically significant
mean here? … added as note to Table 10 "* No statistically
significant effect of intervention on outcome (in
either … values here instead of just
NS
We have chosen to emphasize effect sizes of
results reported to be statistically … significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
May 01, 2019 - There may be significant variation in outcomes of
different treatments in specific subpopulations. … LOD
Live birth (any/
patient)
1 SR107 (8
studies, 1,034
women)
No difference: No statistically … Expectant
Management
Live birth 1 SR160 (3 studies,
370)
Improvement: A significant
increase in … Ever use of clomiphene
citrate was not statistically significantly
associated with maternal ovarian … IVF was associated with a
statistically significant increased risk of
all ovarian neoplasms and borderline
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning-quality_research.pdf
September 01, 2012 - A list of the most statistically significant over- and
underrepresented terms are shown in Appendix … significant (P = 0.09). … The nurse QODD showed significant improvement (pre, 63.1; post, 67.1; P <
0.01) and there was a significant … significant (P > 0.2). … significant (P < 0.05).
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
December 01, 2013 - After 56 weeks of treatment, liraglutide provided statistically significant
improvements in all measures … All differences for both doses of
liraglutide were statistically significantly different from placebo … All differences between
liraglutide and placebo were statistically significantly different and the … Both differences between liraglutide 3 mg and placebo were statistically
significant…liraglutide was … Lorcaserin phase 3 clinical trial in patients with
type 2 diabetes shows statistically significant
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
December 29, 2015 - Only about 30% of patients achieve overall gout
control, so a significant unmet need exists for more … ES-5
Key Expert Comments: Experts commenting on this intervention stated that a significant
unmet … In phase III trials,
patients treated with secukinumab yielded a significant improvement in American … At 16 weeks, patients who received secukinumab 75 mg did
not have significant improvements in ASAS20 … Patients treated
with lesinurad 200 mg and febuxostat did not achieve a statistically significant improvement
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
June 01, 2022 - One small RCT18 (n=80)
found no statistically
significant difference on
reduction of pain scale at … One small RCT6 (n=88) found
no statistically significant
difference between
chlorpromazine and
prochlorperazine … IV, 12.5 mg
once over 30 minutes
2 hours There was no statistically significant difference on
reduction … IV, 10
mg/50 mL dextrose 5% in
water, once over 20 minutes
2 hours There was no statistically significant … IV, 10 mg
metoclopramide plus
placebo once
45 minutes There was no statistically significant difference
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
September 23, 2014 - Methods: The criteria are standard and a priori make sense, however, the
exclusion has led to a significant … With
significant modifications to the introduction and conclusions, the manuscript
may be valuable … This
evidence suggested a slight advantage of EUS-
FNA, but the difference was not statistically
significant … two studies that directly compared the
technologies (all patients received both tests), PET-
CT had statistically … significantly better specificity,
and also had a higher sensitivity but was not
statistically significantly
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
June 01, 2013 - the number needed to treat to achieve one
event of a patient-centered outcome as the reciprocal of
statistically … significant ARDs in rates of outcome events
in the active and control groups. … Few trials reported statistical power to
detect statistically significant differences in outcomes. … Using this statistically significant risk difference, we
estimated that 181 children (95% CI, 52 to … Off-Label Pharmacologic Agents: Magnesium Oxide
A single RCT demonstrated no significant differences
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
April 01, 2015 - Discrepancy in conclusion means one
estimate shows statistically significant difference and the other … not (i.e., the
4
combined estimate using the mean difference based on the change score shows a statistically … significant difference, while using the followup score does not; or vice versa). … when
using change score, and one showed significant result when using the followup score. … when using change score and two showed significant differences when using the
followup score.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_executive.pdf
October 01, 2010 - A p-value of <0.05 was considered
statistically significant for all analyses. … In controlled trials suitable for pooling, significant
improvements in height were observed for patients … In controlled trials, significant
improvements in weight were observed for patients
with CF receiving … In this trial, no
significant differences were seen between the higher
and the lower dose groups for … The
authors of the analysis did not report p-values or
whether the comparisons were statistically significant