-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - macroembolus, or (2) a myocardial blush grade (MBG) of 0 or 1)—has been
associated with larger infarcts, more significant … Poor (high risk of bias) These studies have significant flaws that imply biases of
various types that … For all analyses, a p-value of <0.05 will be
considered statistically significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
October 01, 2010 - To this end, even though it is statistically flawed, it may
be reasonable to compare published controlled … Results In general, the limitation of the available studies were not completely
discussed (except statistically … Discussion Rates of Stroke: “There is a moderate level of evidence to show that
there was no statistically … Both studies reported large and statistically significant
improvements in SF-36 scores (over 30 point … At 12 months, the physical and mental
summary scores were statistically significantly higher in the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - Differences between linagliptin and placebo were statistically
significant. (1 mg, P < 0.01; 5 mg and … No significant weight changes. … diabetes 18 months
Change in
baseline
HbA1c
Avandamet was better than metformin in achieving statistically … for the change in total
cholesterol (p = 0.0006) and LDL cholesterol (p = 0.0056) to week 80
were statistically … The between-
group difference in hypoglycemia was not statistically significant (8.4 and
4.3% with sitagliptin
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
June 28, 2013 - significant, it should be evidence from the CI. … If it is really < 0.1, then this difference is not
statistically significant, and the wording “tended … Peer Reviewer #4 Results Page 87 [=43], line 7 and throughout manuscript - the term
“statistically significant … ” is redundant - please just say “significant.” … We think that there is a distinction between
statistically significant and clinically significant and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_clinician.pdf
October 01, 2015 - evidence is insufficient
* An NA entry for NNT indicates that the relative risk (95% CI) was not statistically … significant
and that an NNT was not calculated.
** The composite endpoint comprises all-cause readmission
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - Smoking during pregnancy can result in
significant complications for the pregnant
woman, her fetus, … aDemonstrated effectiveness at end of pregnancy but was no longer significant at 6 months postpartum. … Only one of the seven studies that reported gestational
age had statistically significant results, with … No studies
found statistically significant differences in the incidence
of preterm birth, neonatal … There is low strength
of evidence for no significant effect on preterm birth and
NICU admission.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - This has created a significant void in the armamentarium of
surgeons or anesthesiologists in their efforts … This pre-defined endpoint was statistically
significant at p=0.03. … This is a significant amount
of in-hospital use, particularly considering the enormous
variation in … But we determined that these strategies of
examining dosing had significant drawbacks, including: 1) … The report
continues to note the statistically significant findings based on
meta-analysis of rFVIIa
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - ; OR=odds ratio;
PPV=positive predictive value; RR=relative risk; Sens=sensitivity; SS=statistically … significant
F-10
Appendix Table F2. … ; OR=odds ratio; PPV=positive predictive value; RR=relative risk; Sens=sensitivity; SS=statistically … significant
F-17
Appendix Table F3. … ; RR=relative risk;
SS=statistically significant; VEpeak=peak ventilation in one minute; Vo2-peak=peak
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
November 14, 2017 - What is clinically significant is somewhat
subjective, but it is a critical question. … That would also have given more statistical
power to find significant pooled effects. … between
intervention and control conditions, generally “usual
care,” have been small, although usually statistically … significant. … describe
the improvement in depressive symptoms with
collaborative care over usual care as being statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
December 01, 2024 - o Studies were consistent in failing to find statistically significant
associations between treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-exe-sum.pdf
April 01, 2025 - reduction of SAs and SI at the end of 6
months, but there were no significant differences on suicidal … adolescents with mood
disorders (aged between 9 and 17 years; 65% were female) found lower but not
statistically … significant different rates of suicidal events compared with enhanced usual
care (mostly involving … Two RCTs23, 29 found no significant difference on suicide outcomes to
support followup care or contact … Significant
heterogeneity in interventions, comparisons, outcomes, and terms used to describe
suicide
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
January 30, 2014 - "
screening"is"warranted,"and"another"study"that"found"that"no"items"on"the"PHQK9"demonstrated"
statistically"significant"or"meaningful"differential"item"functioning"attributable"to"TBI … The"study"found"a"significant"reduction"in"hopelessness"
associated"with"CBTh"however,"there"was"no"significant"reduction"in"depressive"symptoms"or … (
March(2012(
Assessment:(Current(
One$new$study$showed$that$no$item$of$the$
PHQ"9$demonstrated$statistically … March(2012(
Assessment:(Current(
One$new$study$showed$
that$no$item$of$the$PHQ"9$
demonstrated$statistically … $There$were$
no$significant$reduction$in$
depressive$symptoms,$and$
a$non"significant$trend$
towards
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies
Quantitative Synthesis
Chapter 3. Choice of Statistical Model for Combining Studies
Prepared for:
The Agency for Healthcare Research and Quality (AHRQ)
Training Modules for Systematic Reviews Methods Guide
www.ahrq.gov
Presenter…
-
effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
May 26, 2016 - have revised the methods section to
clarify what we mean by clinical significance:
“When there were statistically … significant
differences between treatment groups in
specific LUTS/BPH outcomes, we
interpreted efficacy … A potential for
significant blood pressure reduction using both classes together is also noted. … when it is
statistically significant and the weighted
mean difference is at least half of the MDD. … Maybe instead they could
say "While vardenfail use was associated with significant improvement in mean
-
effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
March 15, 2016 - We recognize that the
results of individual studies
were often equivocal or not
statistically significant … PubMed, only two of
the thirteen studies examining tacrolimus minimization
in Table 9 showcased a statistically … significant benefit
in any of the outcomes measured, and that was only in
eGFR.1,2 Otherwise, the … We recognize that the
results of individual studies
were often equivocal or not
statistically significant … ill-advised given the
challenge of documenting a single RCT asserting that
reduced dose tacrolimus statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - No significant difference
for PANSS (low SoE, 20 RCTs). … For all significant findings, the
SGA was preferred. … Perphenazine vs. quetiapine No significant difference in HRQoL (1 RCT). … Perphenazine vs. ziprasidone No significant difference in HRQoL (1 RCT). … Overall, there were few significant
differences of clinical importance.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
October 01, 2012 - studies did not report effect size but
only a p value, we calculated the
percentage of studies with a statistically … I would report some measure of effect size rather than
statistically significant results. … the only
way to include all studies (which reported
results in many different ways) was to
report statistically … significant results
24h 4. … significant effect
on the outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/outcomes-dental-services-rapid-research.pdf
May 01, 2025 - comprehensive dental treatment reported that those who received
comprehensive dental treatment had statistically … as poor oral hygiene, neglected oral health
problems, and reduced access to dental services, play a significant … • Patients who received comprehensive dental treatment had statistically significantly
higher rates … There were statistically significant
differences in all reported outcomes.23 Patients who received … Significant Findings of the
Treatment Group vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - the meta-analytic results, we used equation 39 in
Trikalinos et al. (2013)17 to compare the tests statistically … If a comparison was not statistically
significant, two reviewers independently judged whether
the … The first two types of conclusions required a statistically
significant difference for either sensitivity … or specificity
(or both), whereas the third type of conclusion required a
nonstatistically significant … significant for specificity but not for sensitivity.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
February 01, 2012 - Studies showed no significant
difference for depression and a significant difference for
mania favoring … SGA (3 RCTs, 1 PCS) Low No significant difference.
symptoms
Clozapine vs. olanzapine Low No significant … ) Low No significant difference. … Low No significant difference.
(1 RCS, 1 PCS)
Olanzapine vs. quetiapine Moderate Significant effect … No significant difference.