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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - JACC 2017; 69:2779-90] demonstrated a
statistically significant ~5x increase in
stroke/systemic embolism … but no statistically
significant difference in bleeding with reduced dose
vs standard dose apixaban … significant reduction in cardiovascular death. … The
intended meaning appears to be not “statistically
significant”, which is a different concept. … We have globally clarified text
to read “no statistically
significant…”
94.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
January 01, 2010 - The findings from this study
were not significant for the primary endpoint
[only a 15% reduction in … treatment
group would not be considered clinically
meaningful with immunotherapy (even if it were
statistically … significant; which it is not). … Furthermore, our CER did not find significant
differences between the European data and the U.S data … [In fact, of the
multiple endpoints assessed (>20), none were
statistically significant (in favor of
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
January 01, 2012 - “In a sensitivity meta-analysis that included only the
three quality A or B studies, a statistically … “In a sensitivity meta-analysis that included only the
three quality A or B studies, a statistically … The data on medication adherence should be provided even
if it is non-significant. … “In a sensitivity meta-analysis that included only the
three quality A or B studies, a statistically … The questions posed are largely relevant and
significant.
Thank you.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
December 01, 2011 - No reflow has been associated with larger
infarcts, significant left ventricular systolic
dysfunction … For
all analyses, a p-value of <0.05 was considered
statistically significant. … The
controlled observational studies found no significant
impact of catheter aspiration device use on … RCTs evaluating treatment effect stratified by
subgroups found the following: (1) no statistically
significant … in mortality
risk, although a single trial found a significant
reduction in MACE.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
May 01, 2024 - Over
4 years, no statistically significant difference was found in MRSA infections
(including surgical … These
differences were not statistically significant, and the study was at moderate risk of
bias. … difficile; or
treatment in long-
term care facility
in previous 6
months
• Statistically
significant … 95% CI
0.061 – 0.347;
p<0.001)
• Statistically
significant reduction
in rate of CRE
infection … (monthly
percent change
-3.57%, 95% CI -6.9
to -0.1; p<0.05)
• Statistically
significant reduction
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - EPC reviewers should designate an evidence base as being inconsistent when different studies show statistically … significant effect sizes in opposite directions. … significant (95% confidence interval [CI], −8 to +1). … significant (95% CI of −8 to −2). … significant (95% confidence interval [CI], −4 to +3).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
September 01, 2008 - This study demonstrated that patients in the basal/bolus therapy group
achieved a statistically significant … Furthermore, a statistically significant greater percentage of patients achieved an HbA1c < 7.0% and … significant). … rate of hypoglycemia with Lispro 75/25 compared with glargine was also statistically significant
(p … Page 68-69: The conclusion that there were no statistically significant differences between premixed
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-evidence-summary.pdf
January 01, 2020 - BFHI-accredited hospitals than control hospitals (by 0.5% to 10%);
differences between groups were not statistically … intervention group had slightly higher rate
of any BF at 6 mos than controls (63% vs. 55%) that was
not statistically … significant). … Magnitude varies by exposure and outcome measure, but only 1
high ROB study reported statistically significant … Apart from two studies (rated
high ROB), no study reported a statistically significant
association
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - adding: two of the three observational studies
suggest…
The adjusted number from Devine et al were not statistically … Please note that this was not statistically significant. … As above, not statistically significant. … PHB was inferior to LEV but
superior to LTG on ADAS-Cog (non-significant for both). … We note that while
retaining a predominant focus on old versus new molecules may
be a statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - However, no significant between- group difference were
observed in two pivotal trials. 7,8
1. … medical therapy
“There was no significant between-
group difference in systolic blood
pressure; the … Quantitative signals (B1-B2)*
Change in statistical significance (B1)
Refers to a situation in which a statistically … significant result in the original CER is now NOT
statistically significant or vice versa- that is … a previously non-significant result become
statistically significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician-2016.pdf
January 01, 2016 - ↔ = no significant difference between the two interventions; ↓= statistically significant reduction
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - distress
or impairment
• Disturbance causes clinically significant distress or impairment in social … N=91) Insufficient
Loss of diagnosis Both trials favor exposure, but meta-analysis did not find a
statistically … significant difference
between the two groups. … point estimates favored placebo
(more adverse events with medications), but differences
were not statistically … significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - significant. … None of these studies reported a statistically
significant difference in pain between placebo and pregabalin … None of the studies found a statistically significant difference between placebo
and pregabalin in terms … significant. … significant difference.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - This finding was, however, statistically significant
only for the comparison with the Framingham
categorical … significant
differences in discrimination, reducing the strength
of evidence. … This study showed no statistically significant
difference in discrimination between the two scores … significant differences in discrimination (low strength
of evidence) … significant differences in discrimination
(low strength of evidence).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
February 01, 2013 - significant differences in the requirement for blood transfusion. … significant. … These findings were not statistically significant and had very wide
confidence intervals.
6
Table … significant difference between PCI
and CABG in either men or women. … significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
July 01, 2013 - significant. … After 56 weeks of treatment, liraglutide provided statistically significant
improvements in all measures … Both differences between liraglutide 3 mg and placebo were statistically
significant…liraglutide was … According to the press release, patients taking 3 mg liraglutide experienced statistically
significant … Lorcaserin phase 3 clinical trial in patients with
type 2 diabetes shows statistically significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - Differences in AHI
between tonsillectomy and watchful waiting groups were
statistically significant … In the study
of electrocautery tonsillectomy, differences in return to
normal activity were not statistically … depending on time period) than did those
in the total tonsillectomy arms, though differences were
not statistically … significant in three studies. … Group differences were
not statistically significant in the electrocautery study.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
January 01, 2014 - significant result. … Assessments at 6 months posttreatment compared with baseline
revealed statistically significant differences … Statistically significant improvements in all
clinical scores (International Knee Documentation Committee … At
6 months, investigators reported that tofacitinib showed statistically significant reductions in … After 3 months of treatment, patients receiving tofacitinib showed a
statistically significant reduction
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
October 29, 2012 - • KQ1, 2, 3, 4, 5 and 6 up to date
• Expert opinion: conclusions still valid
• There are no new significant … Quantitative signals (B1-B2)*
Change in statistical significance (B1)
Refers to a situation in which a statistically … significant result in the original CER is now NOT
statistically significant or vice versa- that is … a previously non-significant result become
statistically significant.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
November 06, 2012 - We downgraded
strength of evidence if risk of bias was moderate or
high, if heterogeneity was statistically … significant, or
if estimates were inconsistent or imprecise. … low-resistance strength training (10 percent of one
repetition maximum), but the differences were
statistically … An effect may be statistically significant but
be too small to be clinically significant. … appear to be equally effective" would be a
more valid conclusion than "it's not statistically significant