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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
December 31, 2017 - trauma
• Failure to recall an important
aspect of trauma
• Loss of interest or participation in
significant … disturbance
• Duration of disturbance symptoms is more
than 1 month
None
Criterion F: Clinically significant … or impairment
• Duration of disturbance symptoms
is more than 1 month
Criterion G: Clinically significant … PTSD
The public health importance of this investigation is paramount because PTSD is associated with
significant … A “poor” study has significant bias (e.g., stemming from serious errors in design or
analysis) that
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - results below by category of
intervention, providing data about adverse events when
available and statistically … Studies consistently reported
significant improvement in measures of quality of life
symptoms (days … Four studies reporting the outcome consistently
noted significant improvements in quality of life measures … Endometrial Ablation
One fair quality study addressed endometrial ablation
and reported significant … None were statistically powered
to examine effect modification by characteristics to
answer questions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - and mortality associated
with preterm birth represent untold
distress for families, as well as significant … The five studies using
suppositories observed a statistically significant
prolongation of gestation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
October 07, 2011 - significance as in this example distracts from the more important
question of whether this is clinically significant … Yes, the p>0.5 is to indicate that there is no
significant difference between the two groups
discussed … We note that Peto ORs are often used in cases where
reporting small differences may be significant, … mechanism of action, safety profiles [4], and varying degrees of
beneficial effects [5] may play a significant … notion that “class
effect” may not occur consistently and that individual treatments have
potentially significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
May 26, 2017 - We chose not to search the Web of Science
database given its significant overlap with
MEDLINE and PsycInfo … They
are also frequently adapted to be targeted to
specific study participants given the significant … report that methodologic rigor is
lacking in the evidence base; however, we
attempted to balance significant … Both
Schaaf, et al, 2014 and Pfeiffer, et al, 2011 found statistically significant
improvements in
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
February 01, 2018 - Quantitative Synthesis: Chapter 5. Network Meta-Analysis
Quantitative Synthesis
Chapter 5. Network Meta-Analysis
Prepared for:
The Agency for Healthcare Research and Quality (AHRQ)
Training Modules for Systematic Reviews Methods Guide
www.ahrq.gov
Presenter
Presentation Notes
Prioritization and Selection of Harms…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-substitute_0.pdf
October 03, 2019 - Patients with chronic wounds are burdened with loss
of function, wound recurrence, and significant morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
March 01, 2016 - effects between antiretrovirals and the numerous other medications taken
for chronic diseases can pose significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-table-E-5.xlsx
January 01, 2023 - 4.56 (3.27-6.20) Univariate analysis for age, BMI, gender, treatment type, prior cannabis exposure; significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
December 11, 2012 - Comment Response
Peer Reviewer #3
General
Comment
The authors have identified a topic of very significant … within stage II and III disease, there are 6
different subtypes of patients for whom there are very significant … Peer Reviewer #5
Results Table 6 implies absence of ECOG scores -- reported and statistically
analyzed … Discussion/
Conclusion
Overall, the authors concluded and stated that the results indicate
there is significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
January 01, 2019 - Results are considered significant at the 0.05 level.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
February 01, 2014 - data for most outcomes
because of the lack of outcomes meeting our criteria for
meta-analysis and significant … instances, the studies
did not report a mean difference or point estimate, stating
only that there was no significant … Second, we excluded non–English-language
publications, although we do not believe this introduced
significant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-map-technical-brief-49-disposition-comments.pdf
September 05, 2024 - Disposition of Comments_Technical Brief No. 49: Evidence Map on Home- and Community-Based Services and Person-Centered Care for Older Adults
Technical Brief Disposition of Comments Report
Title: Evidence Map on Home- and Community-Based Services and Person-Centered Care
for Older Adults
Draft repor…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
February 01, 2013 - The review found that few studies of combined PT modalities demonstrated no
statistically significant … Investigators will need to collect
data on known confounders and statistically adjust
in analysis. … The review found that few studies of combined PT modalities demonstrated no
statistically significant … valid with a large sample size and the collection of many potentially
confounding variables used to statistically … Importance:
Represents a significant disease burden, large proportion, or priority population.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-survivor-care-transition_disposition-comments.pdf
March 18, 2014 - But even looking at the 9 studies there
was significant variation. … 38
Commentator &
Affiliation
Section Comment Response
TEP Reviewer 5 Overall Comments A significant … Even without a shortage, there
are significant problems because it is not clear
who should be caring … Research has also shown that a majority of
cancer survivors will have significant impairments
that … There is also emerging
data which demonstrates that survivors have
significant downstream rehabilitation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ongoing-studies-evidence_research.pdf
December 01, 2010 - The four were selected because they
represented topics with significant research activity and they represented … Searching for ongoing studies may not warrant a
significant investment of resources. … completed in a
manner that contributes useful evidence, searching for ongoing studies may not warrant a
significant
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
February 01, 2016 - was associated with
infrequent direct complications, including hematoma
(4.9 percent), clinically significant … Body Mass
Index
5 Insufficient
Conflicting and non-significant results in studies make it difficult … Carcinoma
Our findings demonstrated a high positive predictive value
of renal mass sampling but a significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - Yes Partial reporting of prespecified
outcomes (e.g., secondary not primary
outcomes; only significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
February 22, 2019 - Research Protocol: Care Interventions for PeopleWith Dementia (PWD) and Their Caregivers
Evidence-based Practice Center Systematic Review Protocol
Project Title: Care Interventions for People With Dementia (PWD) and their
Caregivers
I. Background and Objectives for the Systematic Review
Rising rates of de…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
July 01, 2013 - 1
Comparative Effectiveness Review
Number 120
Treatments for Seasonal Allergic Rhinitis
Executive Summary
Background
Seasonal allergic rhinitis (SAR), also
known as hay fever, is an allergic reaction
in the upper airways that occurs when
sensitized individuals encounter airborne
allergens (typically tree, gras…