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Total Results: 1,179 records

Showing results for "statistically significant".

1061. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
      February 01, 2018 - This enrollment strategy, while practical, has the potential to introduce significant bias for numerous … this effect can provide insights into the impact of the missing data as well as how to report and statistically

1062. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
      April 01, 2007 - Because certain requirements may have significant cost implications, a risk-based approach to developing

1063. Breast-Abnormalities-Tests-Update Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_executive.pdf
      February 01, 2012 - early-stage cancers who mistakenly get triaged into “return to normal screening” may experience a significant … Health Care Program 2 further assessment after a screening mammography do not have cancer, and significant … prevalence of disease in the study population and whether or not the image readers were blinded was statistically … that whether the studies blinded the image readers and accounted for inter- reader differences were statistically … Angle between 1 and 4 min gives the most significant difference in time-intensity curves between benign

1064. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
      September 01, 2011 - To statistically pool studies using these two outcomes, would require converting all outcomes into … Further in Table 32 (p. 137), the language about ‘small but statistically significant effects’ does … The pooled results do not show a significant benefit, nor do individual trials. … Not a single study showed a significant benefit in pooled results, and neither did the metaanalysis.

1065. Medical Therapies for Children With Autism Spectrum Disorder—An Updaterum Disorder--An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-disposition.pdf
      May 26, 2017 - We chose not to search the Web of Science database given its significant overlap with MEDLINE and PsycInfo … They are also frequently adapted to be targeted to specific study participants given the significant … compare the two active groups and, following some threshold criterion, then lump them if there was no significant … TEP Reviewer #5 Results I find it shocking that the authors do not view as significant the observation … However, it seems to me, given the lack of clear evidence that medical treatments have any significant

1066. Infectious Disease Including HIV/AIDS #09 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
      December 01, 2013 -  Key Expert Comments: Overall, experts stated there remains a significant unmet need for earlier … Although a significant capital investment may be required to retrofit frequently touched surfaces in … All but one item sampled had a statistically significant reduction in microbial burden. 86 Clinical … There remains a significant unmet need to reduce these infections because current infection control … Although a significant capital investment is required to retrofit frequently touched surfaces, the

1067. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
      January 30, 2012 - Although generally not as immediately life-threatening as ventricular arrhythmias, AF is associated with significant … to result in death.8-10 Consistent with the nature of these events, AF-related stroke constitutes a significant … have a history of bleeding, are pregnant, and/or are not compliant with treatment (which can be a significant … There were no other significant changes to our KQs or proposed methods. … These studies had significant flaws that might have invalidated the results.

1068. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
      December 27, 2016 - patients with severe COPD (FEV1 <50% predicted normal) and a history of repeated exacerbations, who have significant … patients with severe COPD (FEV1 <50% predicted normal) and a history of repeated exacerbations, who have significant

1069. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
      February 01, 2008 - thromboembolism when anticoagulants are contraindicated or inadequate for management of venous thrombosis with significant … Poor (high risk of bias) These studies have significant flaws that imply biases of various types that … A p- value of <0.05 will be considered statistically significant for all analyses.

1070. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
      February 01, 2008 - thromboembolism when anticoagulants are contraindicated or inadequate for management of venous thrombosis with significant … Poor (high risk of bias) These studies have significant flaws that imply biases of various types that … A p- value of <0.05 will be considered statistically significant for all analyses.

1071. Disposition of Comments Report for Comparative Effectiveness Review #68 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
      July 01, 2012 - It does require significant training and more attention than its invasive ventilation counterpart which … of NPPV in weaning and post- extubation respiratory failure studies were conducted in centers with significant … to judge in practice, since (1) statistical testing is meaningless for ‘Table 1’ differences as any significant … The difference between NPPV and standard care is significant when comparing the criteria for intubation

1072. Disposition of Comments for Comparative Effectiveness Review 133 Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
      May 27, 2014 - That is, you calculated NNT only when the results for an intervention-outcome category was statistically … significant. … say this sensitivity analysis of adding another study showed ‘attenuated effect that is no longer statistically … significant’ rather than saying you found ‘no difference’. … There was also significant heterogeneity.

1073. Psychological and Pharmacological Treatments for Adults with Posttraumatic (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
      December 31, 2017 - trauma • Failure to recall an important aspect of trauma • Loss of interest or participation in significant … disturbance • Duration of disturbance symptoms is more than 1 month None Criterion F: Clinically significant … or impairment • Duration of disturbance symptoms is more than 1 month Criterion G: Clinically significant … PTSD The public health importance of this investigation is paramount because PTSD is associated with significant … A “poor” study has significant bias (e.g., stemming from serious errors in design or analysis) that

1074. Management of Uterine Fibroids - Evidence Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
      December 01, 2017 - results below by category of intervention, providing data about adverse events when available and statistically … Studies consistently reported significant improvement in measures of quality of life symptoms (days … Four studies reporting the outcome consistently noted significant improvements in quality of life measures … Endometrial Ablation One fair quality study addressed endometrial ablation and reported significant … None were statistically powered to examine effect modification by characteristics to answer questions

1075. Progestogens-Preterm-Birth Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
      September 01, 2012 - and mortality associated with preterm birth represent untold distress for families, as well as significant … The five studies using suppositories observed a statistically significant prolongation of gestation

1076. Microsoft Word - 3-DKE274__ACEI-ARB-DRI__Comments_Disposition_Table-21_Jan_2011 cyk _2_.docx (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
      October 07, 2011 - significance as in this example distracts from the more important question of whether this is clinically significant … Yes, the p>0.5 is to indicate that there is no significant difference between the two groups discussed … We note that Peto ORs are often used in cases where reporting small differences may be significant, … mechanism of action, safety profiles [4], and varying degrees of beneficial effects [5] may play a significant … notion that “class effect” may not occur consistently and that individual treatments have potentially significant

1077. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
      May 26, 2017 - We chose not to search the Web of Science database given its significant overlap with MEDLINE and PsycInfo … They are also frequently adapted to be targeted to specific study participants given the significant … report that methodologic rigor is lacking in the evidence base; however, we attempted to balance significant … Both Schaaf, et al, 2014 and Pfeiffer, et al, 2011 found statistically significant improvements in

1078. Quantitative Synthesis: Chapter 5. Network Meta-Analysis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
      February 01, 2018 - Quantitative Synthesis: Chapter 5. Network Meta-Analysis Quantitative Synthesis Chapter 5. Network Meta-Analysis Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Presenter Presentation Notes Prioritization and Selection of Harms…

1079. Disposition of Comments Report for Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
      December 11, 2012 - Comment Response Peer Reviewer #3 General Comment The authors have identified a topic of very significant … within stage II and III disease, there are 6 different subtypes of patients for whom there are very significant … Peer Reviewer #5 Results Table 6 implies absence of ECOG scores -- reported and statistically analyzed … Discussion/ Conclusion Overall, the authors concluded and stated that the results indicate there is significant

1080. Template for Draft Reports (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
      February 01, 2013 - The review found that few studies of combined PT modalities demonstrated no statistically significant … Investigators will need to collect data on known confounders and statistically adjust in analysis. … The review found that few studies of combined PT modalities demonstrated no statistically significant … valid with a large sample size and the collection of many potentially confounding variables used to statistically … Importance: Represents a significant disease burden, large proportion, or priority population.