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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
June 01, 2012 - Understand important statistical and bias issues involved with predictive genetic tests. … Statistical issues must also be taken into account. … Finally, statistical issues must be taken into account when evaluating studies of genetic tests. … Understand statistical issues of particular relevance to genetic tests. … Principle 8: Understand Statistical Issues of Particular Relevance to Genetic Tests (2 of 4)
Jonas DE
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
December 14, 2017 - TEP Reviewer#4 Executive
Summary
What statistical methods used? CART? Latent class? … We have noted that more robust statistical techniques across
aggregated data are needed in order to … TEP Reviewer#5 Methods Yes, the statistical methods used are appropriate. … TEP Reviewer#4 General
Comments
Page ES‐6, lines 6‐7: Clinical or statistical significance? … Exact data and statistical
testing is available in text and tables of full report.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
June 01, 2012 - Understand important statistical and bias issues involved with predictive genetic tests. … Statistical issues must also be taken into account. … Finally, statistical issues must be taken into account when evaluating studies of genetic tests. … Understand statistical issues of particular relevance to genetic tests. … Principle 8: Understand Statistical Issues of Particular Relevance to Genetic Tests (2 of 4)
Jonas DE
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
November 20, 2014 - Yes
Are the statistical methods used appropriate? … Peer Reviewer 4 Methods Data analysis: The statistical analysis methods are generally
sound.
1. … Methods: The statistical method looks at relative risk which
makes no clinical sense for diagnostic … Statistical heterogeneity was discussed in
the text for analyses where it was detected. … As a general rule, the authors of the studies
did not perform any statistical analyses.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - , setting, interventions, and
comparison groups; appropriate measurement of outcomes; appropriate
statistical … Statistical heterogeneity will be addressed using Q Statistic (a p-value <0.10 considered
representative … of significant statistical heterogeneity) and I2 (which assesses the degree of
inconsistency across … Statistics will be performed using StatsDirect statistical software, version 2.4.6 (StatsDirect
Ltd, … Cheshire, England) and MIX statistical software (freely accessible at www.mix-for-meta-
analysis.info
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - A statistical analysis plan describes the
analytical plans and statistical techniques that will be
used … • Formal statistical calculations may be used to specify the size of the registry (number of patients … of observation) needed to measure an effect with a certain level of precision or to meet a specified statistical … products, devices, or processes under study are quantitatively
evaluated beyond simply evaluating statistical … The practice of making inferences about causation largely on the outcome of tests of
statistical significance
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-g-table-surveillance-report-2_0.xlsx
October 08, 2025 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
October 01, 2012 - Evidence-Based
Practice
Evidence-based Practice
Program
The Agency for Healthcare Research and
Quality (AHRQ), through its Evidence-
based Practice Centers (EPCs), sponsors
the development of evidence reports and
technology assessments to assist public-
and private-sector organizations in their
efforts to imp…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
February 22, 2012 - analyses (statistical test/estimation results)
○ Summary measures
○ Sample variability measures … R: A Language and Environment for Statistical Computing.
Vienna ARFfSCAfhwR-po.
31. … R: A Language and Environment for Statistical Computing. … Vienna, Austria: R Foundation for Statistical Computing; 2011.
37. … Journal of
Statistical Software. 2010;36(3):1-48.
39. Hedges LV, Vevea JL.
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - Statistical tools
can be used to create graphical displays and frequency distributions for key variables … This strategy
is simple and is the default approach of many statistical software packages (and thus … This is still a challenge today, but as time goes by,
more statistical packages are upgrading to contain … Statistical Analysis with Missing Data. New
York: Wiley; 1987.
16. Westreich, Daniel. … Statistical Methods in Medical
Research, 21(3):243–256, 2012.
22. Chang, Mark.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - These reviews, which include Clinical (or Medical) Reviews and Statistical
Reviews, are collectively … published trials,
unpublished trials tended to have smaller effect sizes and often failed to demonstrate statistical … Table 1 details the three studies from FDA’s Clinical and
Statistical Review documents for paroxetine
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-f1-f2-2022-update_0.xlsx
January 01, 2022 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-apps-G1-2.xlsx
January 01, 2022 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-app-G.xlsx
January 01, 2022 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other
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effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-g.xlsx
October 08, 2025 - Did the study perform appropriate statistical analyses on potential confounders (e.g., age, other medications
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effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
January 01, 2011 - Part of this discussion
will necessarily deal with sample size issues and
statistical inference for
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
November 30, 2011 - ascertaining exposures, potential confounders, and outcomes; and whether they
performed appropriate statistical … determine the appropriateness of meta-analysis, the clinical and
methodological diversity and assessed statistical … We will use standard
2
tests to assess the presence of statistical heterogeneity among studies, … Statistical heterogeneity will be
explored by using subgroup analysis or meta-regression. … When statistical meta-analysis is not possible, we will group studies by similarity of
intervention
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effectivehealthcare.ahrq.gov/sites/default/files/s103.pdf
October 01, 2007 - Key Words: comparative study, regression analysis, statistical
models, propensity score, bias (epidemiology … In theory, even if the Kaplan–Meier
estimate is sufficient, a Cox model would improve statistical
efficiency … experience,
however, unless the Cox model is extended to include post-
baseline information, the gains in statistical … Currently a major draw-
back is the lack of statistical software for implementing these
methods. … Some uses of statistical models in
connection with the nonresponse problem.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
December 01, 2015 - We assessed statistical heterogeneity in effects
between studies by calculating the chi-squared statistic … manuscript summarizing the findings of this
report for journal submission, we employed a different
statistical … Diagnostic and Statistical
Manual of Mental Disorders. 5th ed. … Statistical approaches for
conducting network meta-analysis in drug development.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
August 10, 2010 - Treatment of preschoolers
Diagnosis of preschoolers may often not adhere to strict DSM (Diagnostic and
Statistical … treatment time is
equal to or greater than
12 months
• Descriptive Statistics
Outcomes Numerical or statistical … results of any
effectiveness or adverse
event outcomes
Numerical or statistical
results of any … settings, funding sources, treatments (type, dose, duration, and provider),
methodological limitations, statistical