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effectivehealthcare.ahrq.gov/sites/default/files/s166.pdf
October 01, 2007 - Bayesian Estimates
The use of Bayesian statistical methods in meta-analy-
sis has been well documented … clinically because they are represented in units of standard
deviation and thus must be judged from a statistical … Statistical Interpretation of the Findings
We found no significant differences in any of the com-
parisons … Changes in statistical conclusions also occurred. … Statistical methods for examining
heterogeneity and combining results from several studies in meta-
analysis
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
March 01, 2011 - Current practices of using statistical testing for baseline difference vary. … in terms of bias, coverage probability, and statistical power. … Statistical Analysis
with Missing Data. 2nd ed. Hoboken, NJ:
Wiley; 1987.
27. … Statistical methods for analysis
of effects of treatment in overviews of
randomized trials. … Statistical Power Analysis for the
Behavioral Sciences. 2nd ed.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
May 19, 2020 - Statistical significance (will be set at a two-sided alpha of 0.05). … We will evaluate statistical heterogeneity among studies using an I2 statistic, and
anticipate statistical … A I2 value greater than 50% will be considered as
substantial statistical heterogeneity. … Statistical power analysis for the behavioral sciences. Hillsdale, NJ: L.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-prepub-final-research-table-rct.xlsx
May 29, 2025 - For yes: overall <20% For yes: per group <10% loss to follow up For yes: explains and uses relevant statistical
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - The ITT
approach provides valid
statistical tests of no treatment
difference hypotheses. … This inconsistency has been
fixed and we now consistently
note whether statistical
significance was … , or statistical significance, does not
measure the size of an effect or the importance of
a result … The prognostic studies of course have the
time element but may also have statistical issues
(e.g., … This can
give the impression that statistical analysis has
shown that the apparent difference is not
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
March 10, 2010 - The
wording of the sentence should be changed to reflect lack of statistical
significance. … I think that this leaves the impression that statistical
significance is equivalent to precision of … estimation (including statistical
significance). … In other words, the paragraph is conflating hypothesis testing
(i.e., statistical significance) with … examined statistical precision. We clarified this in the text.
-
effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
August 27, 2012 - Statistical model estimates preference weights
consistent with observed choices. … – Surrogate markers
– Risk concepts
Consensus among researchers
– Experimental design
– Statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/presentation.ppt
August 01, 2009 - To become familiar with approaches to graphical presentations of findings not synthesized through statistical … population, interventions, and outcomes
Methodological heterogeneity — variation in study design
Statistical … Various statistical models are useful for identifying the level of heterogeneity between studies. … Evidence maps are another way to present data graphically without synthesizing them quantitatively through statistical … Statistical significance status in the primary studies could be based on different analyses (e.g., haplotype-based
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - population, setting, interventions, and comparison groups;
appropriate measurement of outcomes; appropriate statistical … confidence intervals will be calculated by using a DerSimonian and Laird
random-effects model.9
Statistical … appropriate in all
situations, an I2 value of >50 percent has been regarded as representative of important
statistical … to assess for the presence of publication bias.10
Statistics will be performed by using StatsDirect statistical … sizes were on the same side of unity; whether the range of effect sizes was narrow, and
the degree of statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
October 20, 2011 - ascertaining
exposures, potential confounders, and outcomes; and whether they performed appropriate
statistical … appropriateness of meta-analysis, we will consider the
clinical and methodological diversity and assessed statistical … We will use standard
2
tests to assess the presence of statistical heterogeneity among studies and … Statistical heterogeneity will be explored
by using subgroup analysis or meta-regression. … When statistical meta-analysis is not possible, we will group studies by similarity of
intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/s44.pdf
October 01, 2007 - The Researchers’ Domain: Grant Funding, Ethics
Approval, Statistical Analyses
Funding and Ethics Review … size and
stopping rules, participant
flow, recruitment, baseline data
Researcher Grant proposals with statistical … run scientific advisory panel,
matching and blocking, randomization methods,
blinding of analysis, statistical … analyses, assess
generalizability, overall interpretation,
publication of findings
Hypotheses and statistical … expected the policy would
not be targeted by income, so we prepared instead to do the
targeting in our statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
December 09, 2013 - We will not base the decision to perform a meta-analysis on statistical criteria
for heterogeneity. … For all statistical tests, except those for heterogeneity,
statistical significance will be defined … For reporting bias, we will make qualitative dispositions rather than
perform formal statistical tests … Appropriate statistical methods are required to
assess diagnostic tests for replacement, add-on, and … Diagnostic statistical procedures in medical meta-analyses. Stat Med. 1999
Sept;18(17-18):2331-41.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - Certainty of evidence is insufficient due to risk of bias, lack of
statistical significance, extremely … Certainty of evidence for bleeding events is insufficient due to lack of
statistical significance, lack … Lack of statistical significance and conflicting results lead to a certainty rating of
insufficient … The risk of
certainty was rated moderate due to statistical significance and precision. … Certainty of evidence is limited due to lack of statistical significance
30
and risk of bias
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper-2015.pdf
January 01, 2015 - We determined qualitative concordance based on a 2-tiered approach
incorporating changes in statistical … Statistical significance did not change, and
2. … In other words, we did not consider
cases in which a p-value changed statistical significance within … In other words, in 64
percent of comparisons either the statistical significance changed between first … Statistical Power Analysis for the
Behavioral Sciences (2nd Ed.).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
November 01, 2013 - The Statistical Review
describes key statistical issues and findings that affect conclusions regarding … In addition to
the primary endpoint analysis, the statistical reviewer may also address secondary or … The Drugs@FDA site may be searched by the generic or trade drug name (not drug class) for
Statistical … Primary and
secondary endpoints, primary endpoint results, statistical analysis, and statistical significance … Publication decisions revisited: the effect of the
outcome of statistical tests on the decision to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
July 01, 2012 - separate estimates of the
treatment effect in subgroups defined by the predictve test, along with a statistical … Each phase of development is focused on different types of questions, research designs, and
statistical … Research
issues and strategies for genomic and
proteomic biomarker discovery and validation:
a statistical … The statistical evaluation of medical
tests for classification and prediction.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix%20F_0.xlsx
October 08, 2025 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - civilians2,3 and seven to nine percent in Veterans.4,5 Since PTSD was first
included by the Diagnostic and Statistical … symptoms
or symptom clusters without overall PTSD
outcome
• Studies that did not perform formal statistical … Statistical Analysis Method
5. Adjusted Variables in Statistical Analysis
6. … Statistical Analysis Method
6. Adjusted Variables in Statistical Analysis
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research.pdf
October 01, 2016 - Which statistical methods are reliable and valid for analyzing linked
national, State, and community … What are potential sources of bias for these statistical methods?
b. … What are potential sources of bias for these statistical methods?
b. … What are potential sources of bias for these statistical methods?
b. … Statistical Abstracts of the United States.
Washington, D.C: US Census Bureau; 2015.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
June 06, 2011 - methods
for ascertaining exposures, potential confounders, and outcomes; and whether appropriate
statistical … appropriateness of meta-analysis, we will consider the clinical
and methodological diversity and assessed statistical … We will assess the presence of
statistical heterogeneity among studies by using standard
2
tests … Statistical heterogeneity
will be explored by using subgroup analysis or meta-regression. … When statistical meta-analysis is not possible, we will group studies by similarity of
intervention