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effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
November 16, 2010 - November 16, 2010
Assessments of heterogeneity
We will assess the clinical, methodological, and statistical … overlap in confidence intervals of
the included studies will be examined as appropriate to assess statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-treatment_research-protocol.pdf
November 16, 2010 - Assessments of heterogeneity
We will assess the clinical, methodological, and statistical heterogeneity … the degree of overlap in confidence intervals of
the included studies will be examined to assess statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - We tested for statistical
heterogeneity between studies (Q and I2 statistics) while
recognizing that … Statistical Power Analysis for the Behavioral Sciences.
2nd ed Hillsdale, NJ: L.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-e.xlsx
January 01, 2023 - Did the study perform appropriate statistical analyses on potential confounders or otherwise control
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - data necessary to calculate binary effect sizes
will be published and the data can be analyzed using
statistical
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-no-touch-modalities.pdf
May 01, 2022 - One additional pre/post study found VHP lowered CDI (no
statistical testing performed). … 0.15 to 1.81, p=0.30).
1 additional pre/post study found
decreased CDI rates (but did not
perform statistical
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - EPCs should not use results from statistical tests as the sole determinant of the
presence of inconsistency … because of potential problems in their interpretation and lack of
statistical power.45,46 No single … measure is ideal, so EPCs need to explore heterogeneity by
considering several statistical approaches … This gap in data precludes
not only statistical testing of heterogeneity but also qualitative assessment … Publication and related bias in meta-analysis: power of statistical tests
and prevalence in the literature
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
March 01, 2016 - Background
Dementia and Agitation and
Aggression
The American Psychiatric Association’s
Diagnostic and Statistical … However,
because the effect size was unlikely to be clinically
meaningful, the statistical difference … In:
Diagnostic and Statistical Manual of Mental Disorders, 5th ed. … The R Project for Statistical
Computing. R Foundation for Statistical Computing; 2008. … Stata Statistical Software: Release 13. College Station,
TX: StataCorp LP; 2013.
26.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_executive.pdf
May 01, 2013 - the four experimental studies, three
found effects in a positive direction, but only one reached
statistical … an increase among 7 percent of providers, the
other reporting RR=1.82) but neither result achieved
statistical
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-disposition-comments.pdf
December 21, 2023 - Disposition of Comments_Comparative Effectiveness Review No. 264_Social and Structural Determinants of Maternal Morbidy and Mortality: An Evidence Map
Comparative Effectiveness Review Disposition of Comments Report
Title: Social and Structural Determinants of Maternal Morbidity and Mortality: An
Evid…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - Variable
levels of statistical heterogeneity were detected in
the base case analyses, and in a few … A higher level of
statistical heterogeneity was detected in the
evaluation of PE. … For the ‘borderline’ changes in statistical significance, at least one of the
reports (the original … A higher level of statistical heterogeneity was
detected in the evaluation of PE. … A higher level of statistical heterogeneity was detected in the evaluation
of proximal DVT and major
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
November 28, 2012 - secondary outcomes
o Follow-up frequency and duration
o Data analysis details, including:
– Statistical … analyses (statistical test/estimation results)
Test used
Summary measures
Sample variability … o Did the analysis of outcome data incorporate a method for handling confounders such
as statistical … study population
o Well-described intervention
o Use of validated outcome measures
o Appropriate statistical … The magnitude of statistical
heterogeneity will be examined by using I2, while acknowledging potential
-
effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
May 26, 2016 - All other trials and the pooled results showed
no statistical difference. … The statistical methods used are also appropriate.
Thank You. … TEP Reviewer
#4
Methods Diagnostic criteria and statistical methods are appropriate, emphasizing … criteria, multiple
reviewers, carefully managed data extraction and outstanding application of modern
statistical … , 2016
10
Commentator
& Affiliation Section Comment Response
Peer Reviewer
#3
Methods Statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - CER 244 Evidence Summary: Safety of Vaccines Used for Routine Immunization in the United States: An Update
Comparative Effectiveness Review
Number 244
Safety of Vaccines Used for Routine
Immunization in the United States: An Update
Evidence Summary
Main Points
Background and Purpose
Considere…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicide-prevention_disposition-comments.pdf
October 04, 2016 - Peer Reviewer
#1
Methods Yes, although really there are not any statistical methods,
but that is … Search
criteria explicitly stated and logical definitions for outcome
measures and statistical methods … The statistical
methods are appropriate.
Thank you for your comment. … Statistical methods used also appear
appropriate.
Thank you for your comment.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Layout 1
Background
Breast cancer is the most frequently
diagnosed noncutaneous cancer and the
second leading cause of cancer death after
lung cancer among women in the United
States. In 2008, an estimated 182,460 cases
of invasive breast cancer and 67,770 cases
of in situ breast cancer were diagnosed, and
40,480 wo…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/high-cholestorol-medicines-update_research-protocol.pdf
December 31, 2013 - Statistical significance (will be set at a two-sided alpha of 0.05). … with the DerSimonian and Laird formula for
calculating between-study variance.37 We will evaluate for statistical … heterogeneity among
studies using an I2 statistic and anticipate statistical heterogeneity. … A value greater than 50
percent will be considered to have substantial statistical heterogeneity.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - population, setting, interventions, and comparison groups; appropriate
measurement of outcomes; appropriate statistical … Statistical heterogeneity will be addressed using the I2 statistic to assess the degree of
inconsistency … 100 percent with values of 25
percent, 50 percent and 75 percent representing low, medium and high statistical … Statistics will be performed using StatsDirect statistical software, version 2.4.6 (StatsDirect
Ltd,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - exposures;
specifying outcomes and covariates; and addressing confounding, comparison cohorts, and
statistical … established guidance.44
If we conduct quantitative syntheses (i.e., meta-analysis), we will assess statistical … If
we include any meta-analyses with considerable statistical heterogeneity in this report, we will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov
Published Online: February 19, 2010
1
Evidence-based Practice Center Systematic Review Protocol
Project Title: Technical Brief: Neurothrombectomy Devices for
Treatment of Acu…